- Corrosion Behavior and Inhibition
- Parkinson's Disease Mechanisms and Treatments
- Hydrogen embrittlement and corrosion behaviors in metals
- Business, Innovation, and Economy
- Nerve injury and regeneration
- Concrete Corrosion and Durability
- Alzheimer's disease research and treatments
- Immunotherapy and Immune Responses
- Viral Infections and Vectors
- Global Public Health Policies and Epidemiology
- Autism Spectrum Disorder Research
- Transgenic Plants and Applications
- Genetically Modified Organisms Research
- Genetic Neurodegenerative Diseases
- Neurological disorders and treatments
- Consumer Attitudes and Food Labeling
- Educational Research and Science Teaching
- Conducting polymers and applications
- Tryptophan and brain disorders
- RNA Interference and Gene Delivery
- Animal Virus Infections Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- CRISPR and Genetic Engineering
- Mosquito-borne diseases and control
- Neuroscience and Neuropharmacology Research
Instituto Politécnico Nacional
2005-2023
Center for Research and Advanced Studies of the National Polytechnic Institute
2017-2023
Instituto de Estudios Avanzados
2022
Centro de Investigación en Materiales Avanzados
2014-2020
Mexican Institute of Petroleum
2000-2005
Abstract Background Culex spp. mosquitoes are considered to be the most important vectors of West Nile virus (WNV) detected in at least 34 species United States. In North America, pipiens pipiens, quinquefasciatus , and tarsalis all competent WNV, which is enzootic States has also been equines birds many states Mexico humans Nuevo Leon. There potential for WNV introduced into City by various means including infected on airplanes, migrating birds, ground transportation humans. Little known...
The spreading and accumulation of α-synuclein dopaminergic neurodegeneration, two hallmarks Parkinson's disease (PD), have been faithfully reproduced in rodent brains by chronic, oral administration β-sitosterol β-D-glucoside (BSSG). We investigated whether a single injection BSSG (6 μg BSSG/μL DMSO) the left substantia nigra Wistar rats causes same effects. Mock DMSO injections untreated formed control groups. performed immunostainings against pathological α-synuclein, marker tyrosine...
Chronic consumption of β-sitosterol-β-D-glucoside (BSSG), a neurotoxin contained in cycad seeds, leads to Parkinson’s disease humans and rodents. Here, we explored whether single intranigral administration BSSG triggers neuroinflammation neurotoxic A1 reactive astrocytes besides dopaminergic neurodegeneration. We injected 6 μg BSSG/1 μL DMSO or vehicle into the left substantia nigra immunostained with antibodies against tyrosine hydroxylase (TH) together markers microglia (OX42), (GFAP,...
The Receptor-Binding Domain (RBD) of the Spike (S) protein from Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has glycosylation sites which can limit production reliable antigens expressed in prokaryotic platforms, due to glycan-mediated evasion host immune response. However, regions without glycosylated residues capable inducing neutralizing antibodies could be useful for antigen systems that do not carry machinery. To test this hypothesis, potential NG06 and NG19, located...
An animal model, suitable for resembling Parkinson's disease (PD) progress, should show both, motor and non-motor alterations. However, these features have been scarcely evaluated or developed in parkinsonian models induced by neurotoxins. This protocol provides modifications to original methods, allowing six different behavior tests, which adequately timely emulate the main sensorimotor alterations rat mouse: (1) bilateral alterations, examined vibrissae test; (2) balance coordination,...
Felipe Mondragón-Serrano1, América Padilla-Viveros1, Gerardo Hernández2 and José-Víctor Calderón-Salinas13 Author informationPDFCitations 1Program on Science, Technology Society, Centro de Investigación y Estudios Avanzados-IPN, Unidad Zacatenco, CDMX, MEXICO 2ection Methodology of 3Biochemistry Department, Corresponding author. Correspondence: M. Eng.
Abstract Helminths parasites modulate or escape their host’s immune response by different molecular and cellular strategies. One of these is through the interaction molecules from surface with membrane elements cells, modulating signaling pathways. These trigger, control early macrophages dendritic cells (DC). The aim this study to elucidate macrophage pathways that are activated in a Helminth Parasitic Antigen Fractions (HPAFs) vitro. Our data show HPAFs have biological effect on...
El Etiquetado Frontal de Alimentos y Bebidas Advertencia implementado en México, es una política pública basada evidencia científica que brinda a los consumidores información sencilla clara para la toma decisiones compra informadas. Además promover reformulación productos ultraprocesados hacia opciones más saludables, este etiquetado se caracterizó por ser soporta sobre robusta base nivel nacional e internacional, además haber sido construido con contribución actores distintas disciplinas...
Abstract This exploratory research focused on using patent data analysis to develop a technology roadmap for innovation microbiologically influenced corrosion (MIC) in the oil and gas pipelines advance current understanding of this phenomenon through LENS patents database. Evolution number documents (applications grants) from 1990 2020 demonstrated that MIC pipeline had been an area continuous growth throughout last 15 years. Since 2007 remarkable increase trends records started, reaching...