Abstract Background Catheter ablation (CA) has shown efficacy in managing ventricular arrhythmias (VA) associated with structural heart disease. However, some patients continue to experience refractory VA despite pharmacological therapy and multiple CA attempts. In such cases, additional interventions, including autonomic neuromodulation, have been investigated. Renal denervation (RDN), a technique originally developed treat resistant arterial hypertension, works by inhibiting the afferent...

Abstract Background Among patients with heart failure reduced ejection fraction (HFrEF) a significant proportion of deaths occur due to ventricular tachyarrhythmias. Implantable cardioverter defibrillators (ICD) are recommended in primary prevention reduce sudden death and all-cause mortality symptomatic HFrEF left (LVEF) ≤35%, after at least three months guideline-directed medical therapy (GDMT). However, the trials responsible for inclusion this recommendation guidelines predate use...

Abstract Introduction Complete cardiovascular implantable electronic devices (CIED) removal is recommended for all patients (P) with confirmed CIED infection, regardless of whether there definite evidence device involvement. However, when considering reimplantation, optimal timing following transvenous lead remains unclear. Purpose Our study aimed to evaluate the short and long term effects different reimplantation times in P that underwent due infection. Methods Prospective single-centre...

Serum uric acid (UA) has been shown to be an independent predictor of outcome in the general population and patients with heart failure. There are, however, limited data regarding prognostic value UA context acute coronary syndromes (ACS) particularly medium-term follow up available results are contradictory.Study consecutive admitted ACS (with without ST-segment elevation) at a single-centre care unit. Primary endpoint was all-cause mortality 1-year up. We evaluated if serum is it any added...

BackgroundRed Cell Distribution Width (RDW) prognostic value in patients with Acute Coronary Syndrome (ACS) has been well validated whereas that of Platelet (PDW) is less known.

Atrial fibrillation (AF) ablation represents a safe and effective procedure to restore sinus rhythm. The idea that post-procedural AF episodes - during the blanking period are not considered treatment failure has been increasingly challenged. E-Patch, single-use adhesive electrode, facilitates extended continuous ECG monitoring for 120 h. This pilot study aims assess effectiveness of this ambulatory device investigate whether very-early recurrence correlates with delayed outcomes.

The elderly population admitted for acute myocardial infarction is increasing. This group not well studied in international trials and probably treated with a more conservative approach. To evaluate the presentation treatment of according to age, particularly very patients. We 1242 consecutive patients infarction, assessing in-hospital, 30-day one-year mortality during follow-up each age-group. Patients were divided into four groups age: <45 years (7.6%); 45–64 (43.3%); 65–74 (23.4%); ≥75...

This study aimed to assess whether atrial fibrillation (AF) occurrence or its corresponding daily mean burden (in minutes/day) during the mid late blanking period after pulmonary vein isolation (PVI), predicts AF recurrence.Analysis of consecutive first PVI ablation patients undergoing prolonged electrocardiogram (ECG) monitoring second and third months PVI. The clinical variables, total burden, their relationship with time recurrence were studied.477 a age 56.9 (SD = 12.3) years (63.7 %...

We report the case of a 52-year-old man who presented to our emergency department (ED) after three episodes syncope in seven hours before admission. During his stay ED he had recurrent ventricular tachycardia (VT) requiring external electrical cardioversion. A 12-lead electrocardiogram (ECG) showed short QT (SQT) interval (270 ms, QTc 327 ms), with frequent R-on-T extrasystoles triggering sustained polymorphic VT. After exclusion other precipitating causes, patient was diagnosed as having...

Sudden cardiac death is common in the adult congenital heart disease (ACHD) population. Knowledge and experience about use of implantable cardioverter defibrillators (ICD) ACHD patients very limited. We aimed to characterize a cohort with ICDs.Thirty consecutive submitted an ICD implantation single tertiary center were evaluated. Data on baseline clinical features, defect, indication for ICD, type device, appropriate therapies, ICD-related complication, mortality during follow-up...

Morphological changes induced by industrial noise (IN) have been experimentally observed in several organs. Histological observations of the coronary arteries showed prominent perivascular tissue and fibrosis among IN-exposed rats. The effects on small are unknown. To evaluate histomorphometric IN rat heart arteries. Twenty Wistar rats exposed to during a maximum period seven months 20 age-matched controls were studied. Hearts transversely sectioned from ventricular apex atria...

The elderly population admitted for acute myocardial infarction is increasing. This group not well studied in international trials and probably treated with a more conservative approach.To evaluate the presentation treatment of according to age, particularly very patients.We 1242 consecutive patients infarction, assessing in-hospital, 30-day one-year mortality during follow-up each age-group. Patients were divided into four groups age: <45 years (7.6%); 45-64 (43.3%); 65-74 (23.4%); ≥75...

Aims: There are conflicting data regarding the clinical benefits of device-based remote monitoring (RM).We sought to assess effect RM on long-term outcomes in recipients implantable cardioverter-defibrillators (ICDs).Methods: We assessed incidence adverse cardiac events, overall mortality and device therapy efficacy safety a propensity score-matched cohort patients under compared conventional follow-up.Data hospitalizations, cause death were systematically using nationwide healthcare...

The demonstrated benefits of cardiac resynchronization therapy (CRT) in reducing mortality and hospitalizations for heart failure, improving NYHA functional class inducing reverse remodeling have led to its increasing use clinical practice. However, potential contribution complex ventricular arrhythmias is controversial. We present the case a female patient with valvular failure severe systolic dysfunction, III under optimal medical therapy, without previous documented arrhythmias. After...

Abstract Funding Acknowledgements Type of funding sources: None. Background Evaluation atrial fibrillation (AF) recurrence after AF ablation has been validated by routine ECG and ambulatory 24-h Holter monitoring a 3-month blanking period. However, assessment heart rhythm ablation, conducted with the use intermittent or continuous recording systems, shown that early recurrences are common, often asymptomatic, may predict late recurrences. The E-Patch (Bio Tel Heart) is an innovative thin,...

The heart failure risk status (HFRS) is a validated dynamic tool for score prediction, based on the TriageHF™ algorithm (Medtronic, Minneapolis, MN, USA), occurrence of (HF) event in 30 days following remote monitoring (RM) transmission. aim this study was to evaluate accuracy HFRS predicting an unplanned hospital admission due HF decompensation real-world cohort patients submitted cardiac resynchronization therapy (CRT). We conducted single-center review 40 consecutive patients, under RM,...

Background An ablation catheter and a circular mapping requiring double transeptal puncture (TSP) for left atrial access have been conventionally used fibrillation (AF) ablation. Recently, different operators combined single transseptal technique with 3D high-density catheters pulmonary vein isolation (PVI). Objective This study aims to compare two strategies, vs. TSP, regarding the duration of procedure, radiation time, complication rates, outcomes. Methods Retrospective analysis large...

Implantable cardioverter-defibrillator (ICD) monitoring zones (MZ) provide passive features that do not interfere with the functioning of active treatment zones. However, it is known for certain whether programming an MZ affects arrhythmia detection by ICD. The aim present study to assess clinical relevance in a population patients ICDs. In this retrospective analysis ICDs, or without cardiac resynchronization therapy, primary prevention under remote monitoring, was analyzed and recorded...

The classic transvenous implantation of a permanent pacemaker in pectoral location may be precluded by obstruction venous access through the superior vena cava or recent infection at implant site. When these barriers to procedure are bilateral and there also contraindications technical difficulties performing thoracotomy for an epicardial approach, femoral vein, although rarely used, can viable alternative. We describe case patient with occlusion both subclavian veins high risk...