A5030145035- Migraine and Headache Studies
- Trigeminal Neuralgia and Treatments
- Sympathectomy and Hyperhidrosis Treatments
- Acute Ischemic Stroke Management
- Intracranial Aneurysms: Treatment and Complications
- Neuropeptides and Animal Physiology
- Neurological Complications and Syndromes
- Ophthalmology and Eye Disorders
- Cerebrovascular and Carotid Artery Diseases
- Olfactory and Sensory Function Studies
- Botulinum Toxin and Related Neurological Disorders
- Glycogen Storage Diseases and Myoclonus
- Parkinson's Disease and Spinal Disorders
- Neurology and Historical Studies
- Neurological disorders and treatments
- Nicotinic Acetylcholine Receptors Study
- Biochemical effects in animals
- S100 Proteins and Annexins
- Medical Research and Practices
- Neurosurgical Procedures and Complications
- Medical and Biological Sciences
Central University Hospital of Asturias
2014-2023
New York Proton Center
2020
American Headache Society
2020
Background OnabotulinumtoxinA (onabotA) has shown its efficacy over placebo in chronic migraine (CM), but clinical trials lasted only up to one year. Objective The objective of this article is analyse our experience with onabotA treatment CM, paying special attention what happens after Patients and methods We reviewed the charts patients CM on onabotA. were injected quarterly during first year fifth appointment was delayed fourth month explore need for further injections. Results treated 132...
Cranial autonomic symptoms (CAS) seem to appear in around half of migraine patients.Our aim was analyse the prevalence and profile CAS, mainly cranial parasympathetic (CAPS), a series patients with chronic (CM) according new criteria for current IHS classification.We recruited consecutive CM attending our headache clinic. Five CPAS were surveyed: lacrimation, conjunctival injection, eyelid oedema, ear fullness nasal congestion. They graded as 0 (absent), 1 (present mild) 2 conspicuous);...
Background Cranial autonomic parasympathetic symptoms (CAPS) appear in at least half of migraine patients theoretically as a result the release peptides by trigemino-vascular system (TVS). pain pathways become sensitised repeated episodes TVS activation, leading to chronification. Objective The objective this article is correlate presence CAPS with serum levels vasoactive intestinal (VIP) and calcitonin gene-related peptide (CGRP). Patients methods chronic (CM) were asked about – during...
To determine total pituitary adenylate cyclase activating polypeptide (PACAP) in peripheral blood as a potential marker of the activation parasympathetic arm trigemino-vascular system chronic migraine (CM) case-control study.Women older than 17 and diagnosed CM were recruited. Healthy women with no headache history episodic (EM) served control groups. Total PACAP vasoactive intestinal peptide (VIP) levels determined samples obtained from right antecubital vein by ELISA outside attack having...
Galcanezumab has shown efficacy and effectiveness in the treatment of episodic chronic migraine (CM), however, population represented randomized clinical trials (RCTs) differs from observed real-world setting. To describe long-term tolerability galcanezumab practice patients excluded RCTs.Multicenter prospective cohort study consecutive with high-frequency (HFEM) prior failure to three or more preventive drugs, treated followed up for 12 months.We enrolled 1055 patients, aged 50 (IQR:...
Background The trigemino‐vascular system (TVS) plays a key role in migraine pathophysiology. Glial cells are abundant the TVS and mainly trigeminal ganglion. S100B protein is calcium‐binding protein, found cytoplasm of glial central nervous system, which released response to inflammatory stimuli. Previous works analyzing migraineurs have offered contradictory results. Objective In this case‐control study, we analyzed serum levels as possible biomarker activation chronic (CM). Patients...
Background and purpose Acute tandem occlusions often require carotid stenting. Combination of mechanical pharmacologic therapies in addition to antiplatelet drugs administered prevent acute stent thrombosis might increase the risk intracerebral hemorrhage. We present a protocol regimen based on early post-procedural dual-energy CT (DE-CT). Material methods Fifty consecutive stroke patients with treated stenting after intracranial thrombectomy TICI 2b/3 were reviewed. All received intravenous...
Periodontal infections might represent one of the causative factors for cervical artery dissection. We present a case 49-year-old woman admitted due to headache. The patient had been suffering from right second inferior molar infection with phlegmon 1 week prior admission. On 2 October 2014, went dentist and extraction was performed in morning. In afternoon, began experience hemifacial pain that progressed towards an intense bilateral Neurological status at time admission revealed miosis,...
A pesar de que la cefalea es, con diferencia, el principal motivo neurologico consulta, y complejidad diagnostica terapeutica algunos pacientes, numero consultas monograficas (CC) unidades (UC) es muy reducido en nuestro pais. En este articulo pasaremos revista a los principales argumentos nos permitan, como neurologos, defender necesidad implementacion una CC/UC, dependiendo poblacion se debe atender, todos nuestros servicios neurologia. Para ello deberemos, primer lugar, vencer las...