A5091502509- Metal complexes synthesis and properties
- Synthesis and biological activity
- Inorganic and Organometallic Chemistry
- Crystal structures of chemical compounds
- Free Radicals and Antioxidants
- Synthesis and Characterization of Heterocyclic Compounds
- Thermal and Kinetic Analysis
- Organometallic Compounds Synthesis and Characterization
- Molecular Sensors and Ion Detection
- Nonlinear Optical Materials Research
- Computational Drug Discovery Methods
- Lanthanide and Transition Metal Complexes
- Vanadium and Halogenation Chemistry
- Crystallography and molecular interactions
- Air Quality Monitoring and Forecasting
- Wound Healing and Treatments
- Synthesis and Biological Evaluation
- Climate Change and Health Impacts
- Analytical Chemistry and Chromatography
- Advanced Nanomaterials in Catalysis
- Synthesis and Reactions of Organic Compounds
- Radioactive element chemistry and processing
- Electrospun Nanofibers in Biomedical Applications
- Cancer therapeutics and mechanisms
- Electroconvulsive Therapy Studies
South Valley University
2020-2025
New Valley University
2020-2025
Minia University
1993-2003
West Virginia University
2002
Abstract In this study, four new Mn(II), Fe(III), and Cr(III) complexes with two Schiff base ligands namely, 4-bromo-2-[(E)-{[4-(2-hydroxyethyl)phenyl]imino}methyl]phenol (HL1) 2-[(E)-{[4-(2-hydroxyethyl)phenyl]imino}methyl]-4-methoxy phenol (HL2) have been synthesized characterized. Different analytical spectral methods used to characterize the their complexes. General formulas of [M(L)Cl 2 (H O) ] for FeL1, CrL1 CrL2, [M(L)Cl(H 3 MnL2 were proposed. HOMO LUMO energies, as well electrical...
ABSTRACT Seven new complexes of [Cu(H 2 L) ]I.2H O (C1), L)(HL)]ClO 4 .2H (C2), Ag(H L)NO 3 (C3), Ag (H L)(OAc) (C4), Cd (HL)(OH) (C5), (HL)NO (C6), and (HL)Cl (C7) [N‐phenyl‐2‐(phenylglycyl)hydrazine‐1‐carbothioamide](H have been synthesized characterized by various techniques. All metal are mononuclear in nature, except complex [Ag ] which is binuclear. The (C5–C7) adopt tetrahedral, square planar geometry the copper (C1–C3). DFT calculation performed supports expected structures....
Four new complexes (Ni2+, Cu2+, Ag+, and Hg2+) were prepared from the ligand N-(4-chlorophenyl)-2-(phenylglycyl)hydrazine-1-carbothioamide (H2L). Analytical spectroscopic techniques used to clarify structural composition of chelates. In addition, all chelates tested against bacterial strains HepG2 cell line determine their antiseptic carcinogenic properties. The Ni(II) complex was preferable other Molecular optimization revealed that H2L had highest reactivity, followed by Hg-chelate,...
The main objective of this study is to synthesize and characterize a new three complexes Pd (II), Cu (I) metal ions with novel ligand ((Z)-2-(phenylamino)-N'-(thiophen-2-ylmethylene)acetohydrazide) H
Although salens and imidazoles are well‐studied motifs among bioactive therapeutic agents, their properties when combined in transition metal complexes not well developed. To explore the structure/reactivity of this class compounds, a salen‐based ligand, namely (2,2′‐{1,2‐ethanediylbis[nitrilo(E)methylylidene]}diphenol, S), its binary (MS) ternary (MSI) (I = imidazole; M Co (II), Ni Cu Cd Al (III), La (III)) have been synthesized fully characterized by standard physicochemical theoretical...
Despite the common use of salens and hydroxyquinolines as therapeutic bioactive agents, their metal complexes are still under development. Here, we report synthesis novel mixed-ligand (MSQ) comprising salen (S), derived from (2,2′-{1,2-ethanediylbis[nitrilo(E) methylylidene]}diphenol, 8-hydroxyquinoline (Q) with Co(II), Ni(II), Cd(II), Al(III), La(III). The structures properties these MSQ were investigated using molar conductivity, melting point, FTIR, 1H NMR, 13C UV–VIS, mass spectra,...
Wound dressings created using nanotechnology are known as suitable substrates to speed up the healing of both acute and chronic wounds. Therapeutic substances can be delivered these materials. In this study, a hydrogel loaded with Cu (II) Schiff base 8-hydroxy quinoline complex (CuSQ) solid lipid nanoparticles (SLN) was formulated investigate its wound potential in an excision model rats. The CuSQ SLN were spherical shaped sizes ranging from 111 202 nm polydispersity index (PDI) 0.43 0.76,...
Abstract New complexes of molecular formulae [Cu(H 2 L 1 )I] (B ), L) (ClO 4 ) ](B [Zn (H O)]SO 3 and [Cd(H L)Cl]Cl(B ligand N -phenyl-2-(p-tolylglycyl)hydrazine -1-carbothioamide (B) have been prepared characterized by H-NMR, Mass spectra, FT-IR, elemental analyses, molar conductance, UV–visible magnetic susceptibility measurements, thermogravimetric analysis (TGA/DTG) X-ray powder diffraction before after irradiation. Elemental analyses indicate that the metal 1:1 (metal/ ligand) B or 1:2...
In this study, five novel complexes for Co(II), Ni(II), VO(II), Cr(III), and La(III) ions were synthesized from a tridentate NNO monobasic chelating Schiff base ligand, (Z)‐2‐((pyridin‐2‐ylimino)methyl)phenol (HL). Spectral analytical tools applied to elucidate the structural compositions of new compounds. Then, geometry optimization was conducted all syntheses by Gaussian 09 program via density functional theory method obtain optimal structures most essential parameters. Moreover,...
New Pb(II), Mn(II), Hg(II), and Zn(II) complexes, derived from 4-(4-chlorophenyl)-1-(2-(phenylamino)acetyl)thiosemicarbazone, were synthesized. The compounds with general formulas, [Pb(H2L)2(OAc)2]ETOH.H2O, [Mn(H2L)(HL)]Cl, [Hg2(H2L)(OH)SO4], [Zn(H2L)(HL)]Cl, characterized by physicochemical theoretical studies. X-ray diffraction studies showed a decrease in the crystalline size of that exposed to gamma irradiation (γ-irradiation). Thermal synthesized complexes thermal stability Mn(II)...
Three new Co (II), Ag (I), and Cd (II) ion complexes were created from the ligand, 2-(phenylglycyl)-N-(p-tolyl)hydrazine-1-carbothioamide (H2LB). The structural makeup of compounds was clarified using analytical spectroscopic techniques. Then, Gaussian09 software, geometry optimization done for each synthesis. Furthermore, compound's antibacterial anticancer properties evaluated against different types bacteria HepG2 cell line non-irradiated irradiated complexes, where complex (A1) is higher...
Four novel lanthanide La (III), Ce Nd and Dy (III) complexes with (Z)‐4‐(benzo[d]thiazol‐2‐ylamino)‐3‐((benzo[d]thiazol‐2‐ylimino)methyl)‐2H‐chromen‐2‐one (L) were prepared characterized. The compounds' structural compositions elucidated by the application of analytical spectroscopic methodologies. From physical chemical measurements, general formula for [LnL Cl 3 ]2H 2 O (C1‐C4) was proposed, which proven theoretical measurements. Using cisplatin, gentamicin, ampicillin, ascorbic acid as...
A new series of Pd (II), Cd and Cu(I) complexes with ((Z)‐2‐(phenylamino)‐N′‐(thiophen‐2‐ylmethylene)acetohydrazide)( H 2 L B ) has been prepared. FT‐IR, 1 H‐NMR, electronic spectra, Powder X‐ray, thermal behavior, theoretical methods DNA interaction ligand (II) before after γ‐irradiation are studied. The NMR spectrum the shows signals appear at same position or slightly shift, but intensity bands is higher than irradiated. X‐ray diffraction (XRD) studies exhibited samples in nanorange,...
ABSTRACT Four new VO(II), Cu(II), Ru(III), and Ag(I) chelates were created from the ligand, 2‐(phenylglycyl)‐N‐(p‐tolyl)hydrazine‐1‐carbothioamide(H 2 L). The structures of compounds investigated using analytical spectroscopic techniques supported by theoretical DFT study. In addition, all exhibited strong anticancer effects against liver (Hep‐G2), breast (MCF‐7), colon (HCT‐116) human cancer cell lines. VO(II) complex observed greatest activity with IC 50 reached to 14, 19, 20 μM Hep‐G2,...
A new series of Zr(IV), V(IV), Ru(III), and Cd(II) complexes with the ligand N‐((5‐hydroxy‐4‐oxo‐4H‐pyran‐3‐yl)methylene)‐2‐(p‐tolylamino)acetohydrazide ( H 2 L ) have been prepared. FT‐IR, 1 H‐NMR, electronic spectra, powder X‐ray, thermal behavior methods were applied to elucidate structural composition compounds. Geometry optimization for all synthesized compounds was conducted using Gaussian09 program via DFT method, obtain optimal structures essential parameters. Moreover, antibacterial...
Objective: Indoor pollutants, such as household dust, are increasingly recognized potential contributors to health problems, including sleep disturbances. This study investigates the association between dust exposure and quality among American adults, utilizing data from National Health Nutrition Examination Survey (NHANES) 2005 2006. Methods: Data NHANES were used in a cross-sectional design. Total weight (mg) was primary variable, outcomes included self-reported duration, latency,...
Synthesis and Antimicrobial studies of novel Benzimidazole derivativesParmender Singh Rathee,Ritu Dhankar, Sunny Bhardwaj,Monika Gupta, Rakesh Kumar
The electrochemical behavior of ascorbic acid (AA), dopamine (DA), and uric (UA) on a dl-norvaline-modified glassy carbon electrode (GCE) was studied by cyclic voltammetry. bare GCE failed to distinguish the oxidation peaks AA, DA, UA in phosphate-buffered solution (pH 5.0), while could separate them efficiently. In differential pulse voltammetric (DPV) measurements, modified resolved overlapped responses into three well-defined peaks. Under optimum conditions, anodic peak currents DPV for...
With the aid of hydrazone moiety, a novel Cd(II) chelate with 2-[(4-methylphenyl)amino]-N'-[(Z)-thiophen-2-ylmethylidene]acetohydrazide (H2L) was created and reported. These chemicals' structural makeup clarified through utilization spectroscopic analytical methods. The chelates were molded molar ratio 1:1 M:L formula [Cd(H2L)Cl2]. complex biological activity ligand is investigated. Theoretical measurements supported proposed generic for [Cd(H2L)Cl2] complex. compound's anticancer...
Two new Sm(III) complexes, [Sm(L1)2Cl(H2O)]·3H2O and [Sm(L2)2Cl(H2O)]·2H2O, where HL1 is (E)-4-bromo-2-(((4-(2-hydroxyethyl)phenyl)imino)methyl)phenol HL2 (E)-2-(((4-(2-hydroxyethyl)phenyl)imino)methyl)-4-methoxyphenol, are reported. From the spectral data, it was deduced that two Schiff base ligands existed as monobasic bidentate ON bonded to samarium(III) through deprotonated hydroxyl oxygen azomethine nitrogen adopting an octahedral environment around Sm(III). The optimized structures,...