A5100334662- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- RNA modifications and cancer
- Respiratory Support and Mechanisms
- Neonatal Respiratory Health Research
- Circular RNAs in diseases
- Cancer, Hypoxia, and Metabolism
First People's Hospital of Chongqing
2019-2023
Wuhan University
2017
Zhongnan Hospital of Wuhan University
2017
Abstract: MicroRNAs (miRNAs) have been considered as promising diagnostic biomarkers for many diseases, especially cancers. Numerous studies reported the value of miRNAs in diagnosis osteosarcoma (OS), but results vary greatly across different studies. Therefore, we conducted this meta-analysis to assess prospective diagnosing OS. All relevant articles from prior July 28, 2017 were selected PubMed, EMBASE, Web Science, Cochrane Library, Chinese National Knowledge Infrastructure, and Wan-fang...
Abstract Adenosine monophosphate‐activated protein kinase (AMPK) plays a key role in cellular energy homeostasis and cell proliferation. MicroRNAs (miRNAs) function as posttranscriptional regulators of gene expression biological processes. It is unclear to whether miRNAs are involved AMPK‐regulated Sertoli (SC) To further understand the regulation immature boar SC proliferation, 5‐aminoimidazole‐4‐carboxamide‐1‐β‐D‐ribofuranoside (AICAR) was added activate AMPK. By an Illumina small RNA deep...
Abstract This study was carried out with the objective to identify function prediction of novel microRNAs (miRNAs) in immature boar Sertoli cells (SCs) treated 5‐aminoimidazole‐4‐carboxamide‐1‐β‐D‐ribofuranoside (AICAR), which is an agonist adenosine monophosphate‐activated protein kinase (AMPK) for regulating cellular energy homeostasis. Two small RNA libraries (control and AICAR treatment) prepared from SCs were constructed sequenced by Illumina deep sequencing. We identified 77 miRNAs...