A5112337388- Research on Leishmaniasis Studies
- Trypanosoma species research and implications
- Toxin Mechanisms and Immunotoxins
- Malaria Research and Control
- Ethnobotanical and Medicinal Plants Studies
- Insect Pest Control Strategies
- Parasites and Host Interactions
- Heavy metals in environment
- Diverse Scientific Research Studies
- Mercury impact and mitigation studies
- Aquatic Ecosystems and Biodiversity
- Geology and Paleoclimatology Research
- Parasitic Infections and Diagnostics
- Heavy Metal Exposure and Toxicity
- Parasite Biology and Host Interactions
- Phytochemistry and biological activities of Ficus species
- Essential Oils and Antimicrobial Activity
- Phytochemicals and Medicinal Plants
- Adolescent Sexual and Reproductive Health
- Viral gastroenteritis research and epidemiology
- Environmental Toxicology and Ecotoxicology
- Natural Antidiabetic Agents Studies
- Garlic and Onion Studies
- Cynara cardunculus studies
- Helminth infection and control
University of Eldoret
2012-2025
Kenya Forest Service
2022
Moi University
2010-2012
This study evaluated Ocimum gratissimum and Rhoicissus tridentata for their In vitro antimalarial activity safety. The plant samples collected from Keiyo South in Kenya were processed compounds extracted using inorganic organic solvents. Phytochemical screening, antiplasmodial bioassays, cytotoxicity tests, statistical analyses conducted to validate compare the efficacies of two used traditionally treatment malaria Kenya. O. extracts showed strong inhibition low toxicity, with methanol as...
Malaria is a global health crisis. Drug resistance underscores the urgency of developing new antimalarial treatments. Currently, medicinal plants are being explored for potential solutions, offering hope in fight against deadly disease. This study examines Ocimum gratissimum and Rhoicissus tridentate through comprehensive analyses their phytochemical, nutritional, mineral profiles, aiming to assess malaria treatment. The O. R. aqueous methanol solvents extracts yields were quantified...
Malaria remains a leading cause of morbidity and mortality among children under five years in sub-Saharan Africa. Complicated malaria poses significant threat, necessitating early identification predictors for timely intervention. This study aimed to identify clinical, hematological, cytokine profile complicated Vihiga Highlands, Western Kenya. A cross-sectional was conducted on 309 children. The participants were sampled purposively grouped the categories. Among analyzed clinical groups...
Use of some fish parasites as bioindicators heavy metal pollution has been demonstrated a promising approach because their capacity to bioconcentrate such elements. This study evaluated the effects cestode parasite, Ligula intestinalis, on accumulation lead (Pb), cadmium (Cd), chromium (Cr) and copper (Cu) in cyprinid fish, Rastreneobola argentea, Lake Victoria, Kenya. L. intestinalis/R. argentea model also was assessed bioindicator system for contamination lake. Samples 125 63 parasites,...
Despite advances to targeted leishmanicidal chemotherapy, defies around severe toxicity, recent emergence of resistant variants and absence rational vaccine still persist. This necessitates search and/or progressive validation accessible medicinal remedies including plant based. The study examined both in vivo vitro response L. major infection combined therapy Ricinus communis Azadirachta indica extracts BALB/c mice as the mouse model. A comparative design was applied.BALB/c mice, treated...
Conventional targeted leishmanicidal chemotherapy has persistently remained prohibitive for most economically deprived communities due to costs, associated time accessing health services and duration successful treatment programme. Alternatives are bound be incorporated in rational management of leishmaniasis by choice or default accessibility cultural beliefs. Therefore, there is need rigorously investigate appraise the activity medicinal compounds that may have anti-leishmanicidal...
Objectives: Complicated pediatric Malaria in unstable transmission regions presents a significant health challenge, necessitating comprehensive understanding of the associated hematological and immunological alterations. This study aimed to investigate parameters, chemokine cytokine response children with complicated an malaria region. Material Methods: cross-sectional was conducted Vihiga County, Western Kenya, highland area transmission. Three hundred nine varied phenotypes were recruited...
Natural products and herbicides are potential sources of new selective agents for the treatment important tropical diseases caused by parasites.Leishmaniasis is a major health problem worldwide affects millions people especially in developing nations.There no immunoprophylaxis (vaccination) available Leishmania infections conventional treatments unsatisfactory.Therefore, antileishmanial drugs urgently needed.In this study, activity two (acriflavine trifluralin) plant biocides (triterpenoid...
Background: Kenya is one of the six HIV ‘high burden’ countries in Africa with about 1.6 million people living infection by 2013. Women are more vulnerable to compared men, national prevalence at 7.6% for women and 5.6% men. There were 1441 pregnant Busia County 2013, an estimated 57 new paediatric infections. positive mothers, have a constitutional; human right may want children but timing has be minimize chances transmission. Aim: To establish factors that influence pregnancy decision...
Leishmaniasis is a major public health problem caused by parasite of the genus Leishmania which transmitted through bite an infected female phlebotomine sandfly. However, disease epidemiology on interactions causative agents, reservoir hosts, and vectors in areas where there high prevalence needs to be properly understood inform effective control. The present study was conducted determine natural infection parasites sandfly suspected hosts found caves Mount Elgon Kenya. Sandflies, bats rock...
Aim: The aim of the current study was therefore to determine leishmania parasite infections and blood meal sources in Mt. Elgon, Kenya. Methodology: A total 400 fed female sand flies were randomly selected from sites for source determination. Samples analyzed by ELISA method. Test done bat, hyrax, cat, human. Results : results indicated that females constituted 71.7% flies collected, while males 28.3%. There significant differences Leishmania infection between vector species (F = 4.1671, df...