Betül Köklü

ORCID: 0000-0003-3477-3290
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About
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Research Areas
  • Neuroscience and Neuropharmacology Research
  • Ion channel regulation and function
  • Epilepsy research and treatment
  • Liver Disease and Transplantation
  • Pancreatitis Pathology and Treatment
  • Liver Disease Diagnosis and Treatment
  • Bee Products Chemical Analysis
  • Inflammasome and immune disorders
  • Cerebrovascular and genetic disorders
  • Endoplasmic Reticulum Stress and Disease
  • interferon and immune responses
  • Mitochondrial Function and Pathology
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Complementary and Alternative Medicine Studies
  • Pharmacological Effects and Toxicity Studies
  • Erythrocyte Function and Pathophysiology
  • Advanced Glycation End Products research
  • Medical and Biological Ozone Research
  • Autophagy in Disease and Therapy

Namık Kemal University
2021-2023

Bozok Universitesi
2020-2021

Ministry of Health
2008

Epilepsy is characterized by an imbalance in neurotransmitter activity; increased excitatory to inhibitory activity. Acetylcholine (ACh), serotonin, and norepinephrine (NE) may modulate neural activity via several mechanisms, mainly through its receptors/transporter alterations the extracellular potassium (K+) concentration K+ ion channels. Seizures disrupt regulation of inwardly rectifying (Kir) channels alter receptor/transporter However, there are limited data present on immunoreactivity...

10.3390/life11040276 article EN cc-by Life 2021-03-26

Propolis has become one of the most preferred supplements due to its beneficial biological properties. Organic (water and vegetable oils) chemical (ethyl alcohol, propylene glycol, glycerol) solvents are used for propolis extraction. However, effects these chemicals on health should be taken into account.In this study, extracts were evaluated.32 pregnant Wistar albino rats 64 neonatal/young adults given three different extractions (propylene water, olive oil). Histopathological analyses...

10.1055/a-2010-4009 article EN Zeitschrift für Geburtshilfe und Neonatologie 2023-03-08

Inflammation and hypoxia have an effect on the molecular mechanism of cardiovascular respiratory pathologies accompanying seizures. Against this, Tauroursodeoxycholic Acid (TUDCA) can regulate oxidative stress, inflammation cellular survival by suppressing endoplasmic reticulum (ER) stress. We evaluated expression changes NF-κB p65, TNF-α, HIF1α Kir6.2 proteins associated with seizures in brain stem, heart lung tissues representing autonomous network. Additionally, we examined protective...

10.14715/cmb/2022.68.12.19 article EN cc-by Cellular and Molecular Biology 2023-04-23

Purpose A patient with subretinal and pre-retinal hemorrhage after secondary systemic amyloidosis due to familial Mediterranean fever is presented. Methods Case presentation. Results 30-year-old woman presented painless visual loss in the right eye. The examination demonstrated multiple hemorrhages, massive deposits which may represent amyloid material at left macular region. After 6 months, hemorrhages disappeared, but persisted. Conclusions deposition an uncommon manifestation of fever....

10.1177/112067210801800325 article EN European Journal of Ophthalmology 2008-05-01
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