A5004427603- Neural dynamics and brain function
- Functional Brain Connectivity Studies
- EEG and Brain-Computer Interfaces
- Photoreceptor and optogenetics research
- Stress Responses and Cortisol
- Optical Imaging and Spectroscopy Techniques
- Neuroendocrine regulation and behavior
- Advanced MRI Techniques and Applications
- Ultrasound and Hyperthermia Applications
- Photoacoustic and Ultrasonic Imaging
- Neurotransmitter Receptor Influence on Behavior
- Disaster Management and Resilience
- Atomic and Subatomic Physics Research
- Intensive Care Unit Cognitive Disorders
- Memory and Neural Mechanisms
- Mental Health Research Topics
- Tryptophan and brain disorders
- Neural Networks and Applications
- Long-Term Effects of COVID-19
- Enhanced Recovery After Surgery
- Disaster Response and Management
- Hormonal Regulation and Hypertension
- Cardiac Arrest and Resuscitation
Pennsylvania State University
2019-2024
Wenzhou Medical University
2023-2024
First Affiliated Hospital of Wenzhou Medical University
2023-2024
University of South Dakota
2014-2016
The blood oxygenation level-dependent (BOLD)-based resting-state functional magnetic resonance imaging (rsfMRI) has been widely used as a non-invasive tool to map brain-wide connectivity architecture. However, the neural basis underpinning BOLD signal remains elusive. In this study, we combined simultaneous calcium-based fiber photometry with rsfMRI in awake animals examine relationship of and spiking activity at resting state. We observed robust couplings between calcium signals dorsal...
Rodent models are essential to translational research in health and disease. Investigation rodent brain function organization at the systems level using resting-state functional magnetic resonance imaging (rsfMRI) has become increasingly popular. Due this rapid progress, publicly shared rsfMRI databases can be of particular interest importance scientific community, as inspired by human neuroscience psychiatric that substantially facilitated open neuroimaging datasets. However, such rats...
Abstract The default mode network (DMN) is a principal brain in the mammalian brain. Although DMN humans has been extensively studied with respect to structure, function, and clinical implications, our knowledge of animals remains limited. In particular, functional role nodes, how organization relates DMN-relevant behavior are still elusive. Here we investigated causal relationship inactivating pivotal node (i.e., dorsal anterior cingulate cortex [dACC]) on organization, by combining...
Respiration can induce motion and CO
The architecture of brain networks has been extensively studied in multiple species. However, exactly how the network reconfigures when a local region, particularly hub stops functioning remains elusive. By combining chemogenetics and resting-state functional magnetic resonance imaging (rsfMRI) an awake rodent model, we investigated causal impact acutely inactivating region (i.e. dorsal anterior cingulate cortex) on properties. We found that suppressing neural activity could have ripple...
Abstract Studying brain‐wide hemodynamic responses to different stimuli at high spatiotemporal resolutions can help gain new insights into the mechanisms of neuro‐ diseases and ‐disorders. Nonetheless, this task is challenging, primarily due complexity neurovascular coupling, which encompasses interdependent parameters including cerebral blood volume (CBV), flow (CBF), oxygen saturation (SO 2 ). The current brain imaging technologies exhibit inherent limitations in resolution, sensitivity,...
Resting-state brain networks (RSNs) have been widely applied in health and disease, but the interpretation of RSNs terms underlying neural activity is unclear. To address this fundamental question, we conducted simultaneous recordings whole-brain resting-state functional magnetic resonance imaging (rsfMRI) electrophysiology signals two separate regions rats. Our data reveal that for both recording sites, spatial maps derived from band-specific local field potential (LFP) power can account up...
The surge in critically ill COVID-19 patients caused a shortage of intensive care unit (ICU) beds. Some hospitals temporarily transformed general wards into ICUs to meet this pressing health demand.
Resting-state brain networks (RSNs) have been widely applied in health and disease, but the interpretation of RSNs terms underlying neural activity is unclear. To address this fundamental question, we conducted simultaneous recordings whole-brain resting-state functional magnetic resonance imaging (rsfMRI) electrophysiology signals two separate regions rats. Our data reveal that for both recording sites, spatial maps derived from band-specific local field potential (LFP) power can account up...
Abstract Withdrawal from amphetamine increases anxiety and reduces the ability to cope with stress, which are factors that believed contribute drug relapse. Stress‐induced serotonergic transmission in central nucleus of amygdala is associated states fear. Conversely, stress‐induced ventral hippocampal serotonin (5‐ HT ) levels have been linked coping mechanisms. The goal this study was investigate neurobiological changes induced by stress sensitivity during withdrawal. We tested hypothesis...
Resting-state brain networks (RSNs) have been widely applied in health and disease, but their interpretation terms of the underlying neural activity is unclear. To systematically investigate this cornerstone issue, here we simultaneously recorded whole-brain resting-state functional magnetic resonance imaging (rsfMRI) electrophysiology signals two separate regions rats. Our data show that for both recording sites, band-specific local field potential (LFP) power-derived spatial maps can...
The brain undergoes a protracted, metabolically expensive maturation process from childhood to adulthood. Therefore, it is crucial understand how network cost distributed among different systems as the matures. To address this issue, here we examined developmental changes in wiring and topology using resting-state functional magnetic resonance imaging (rsfMRI) data longitudinally collected awake rats juvenile age We found that increased vast majority of cortical connections but decreased...
<title>Abstract</title> Resting-state brain networks (RSNs) have been widely applied in health and disease, but their interpretation terms of the underlying neural activity is unclear. To systematically investigate this cornerstone issue, here we simultaneously recorded whole-brain resting-state functional magnetic resonance imaging (rsfMRI) electrophysiology signals two separate regions rats. Our data show that for both recording sites, band-specific local field potential (LFP)...
<title>Abstract</title> Resting-state brain networks (RSNs) have been widely applied in health and disease, but the interpretation of RSNs terms underlying neural activity is unclear. To address this fundamental question, we conducted simultaneous recordings whole-brain resting-state functional magnetic resonance imaging (rsfMRI) electrophysiology signals two separate regions rats. Our data reveal that for both recording sites, spatial maps derived from band-specific local field potential...
<title>Abstract</title> Resting-state brain networks (RSNs) have been widely applied in health and disease, but the interpretation of RSNs terms underlying neural activity is unclear. To address this fundamental question, we conducted simultaneous recordings whole-brain resting-state functional magnetic resonance imaging (rsfMRI) electrophysiology signals two separate regions rats. Our data reveal that for both recording sites, spatial maps derived from band-specific local field potential...
<title>Abstract</title> Resting-state brain networks (RSNs) have been widely applied in health and disease, but the interpretation of RSNs terms underlying neural activity is unclear. To address this fundamental question, we conducted simultaneous recordings whole-brain resting-state functional magnetic resonance imaging (rsfMRI) electrophysiology signals two separate regions rats. Our data reveal that for both recording sites, spatial maps derived from band-specific local field potential...
Resting-state brain networks (RSNs) have been widely applied in health and disease, but the interpretation of RSNs terms underlying neural activity is unclear. To address this fundamental question, we conducted simultaneous recordings whole-brain resting-state functional magnetic resonance imaging (rsfMRI) electrophysiology signals two separate regions rats. Our data reveal that for both recording sites, spatial maps derived from band-specific local field potential (LFP) power can account up...
Respiration can induce non-neural artifacts in the resting-state fMRI (rsfMRI) signal. In meantime, as a crucial physiologic process, respiration that directly drive neural activity change, and may thereby modulate rsfMRI Nonetheless, this potential component respiration-fMRI relationship remains elusive. To elucidate issue, we developed platform to achieve concurrent measure of electrophysiology, respiration, whole brain signals, identified respiration-associated network was underpinned by...
Understanding the relationships between neuronal, vascular and Blood oxygenation level-dependent (BOLD) signals is essential for appropriate interpretation of functional magnetic resonance imaging (fMRI) results in relation to corresponding neuronal activity. In this study, we utilized multimodal technique that concurrently measures BOLD fMRI calcium-based fiber photometry signal examine relationship neural spiking activity awake rats. Our demonstrated significant correspondence calcium at...