- Biosensors and Analytical Detection
- Gold and Silver Nanoparticles Synthesis and Applications
- Spectroscopy Techniques in Biomedical and Chemical Research
- Dental materials and restorations
- Phonocardiography and Auscultation Techniques
- Advanced biosensing and bioanalysis techniques
- ECG Monitoring and Analysis
- Advancements in Battery Materials
- Neurological Disease Mechanisms and Treatments
- Corneal surgery and disorders
- Neuroscience and Neuropharmacology Research
- Advanced Optical Imaging Technologies
- Bee Products Chemical Analysis
- Orthodontics and Dentofacial Orthopedics
- Non-Invasive Vital Sign Monitoring
- Dental Erosion and Treatment
- Tendon Structure and Treatment
- Corneal Surgery and Treatments
- Traditional Chinese Medicine Studies
- Acupuncture Treatment Research Studies
- Bacterial Identification and Susceptibility Testing
- Spectroscopy and Chemometric Analyses
- Dental Implant Techniques and Outcomes
- Magnetic Properties and Synthesis of Ferrites
- Dental Radiography and Imaging
Kyung Hee University
2016-2025
Sungkyunkwan University
2004-2023
Korea Institute of Materials Science
2023
Korea National University of Education
2022
Kyung Hee University Medical Center
2010-2019
Kyung Hee University Hospital at Gangdong
2019
Konkuk University
2017
GlobalFoundries (United States)
2017
Binghamton University
2014
Kyung Hee University Dental Hospital
2012-2013
We report the development of a surface-enhanced Raman spectroscopy sensor chip by decorating gold nanoparticles (AuNPs) on ZnO nanorod (ZnO NR) arrays vertically grown cellulose paper (C). show that these chips can enhance signal 1.25 × 107 with an excellent reproducibility <6%. we measure trace amounts human amniotic fluids patients subclinical intra-amniotic infection (IAI) and preterm delivery (PTD) using in combination multivariate statistics-derived machine-learning-trained...
Surface-enhanced Raman scattering (SERS) is an ultrasensitive molecular screening technique with greatly enhanced signals from trace amounts of analytes near plasmonic nanostructures. However, research on the development a sensor that balances signal enhancement, reproducibility, and uniformity has not yet been proposed for practical applications. In this study, we demonstrate potential application detecting or predicting asymptomatic breast cancer human tears using portable spectrometer...
A large-size and full-color three-dimensional (3D) display system without the need for special eyeglasses is demonstrated. With a specially fabricated holographic functional screen with size of 1.8x1.3 m(2), including optimally designed camera-projector arrays video server can fully continuous, natural 3D scene more than 1 m image depth in real time. We explain operating principle present experimental results.
We investigate the mode of action and classification antibiotic agents (ceftazidime, patulin, epigallocatechin gallate; EGCG) on Pseudomonas aeruginosa (P. aeruginosa) biofilm using Raman spectroscopy with multivariate analysis, including support vector machine (SVM) principal component analysis (PCA). This method allows for quantitative, label-free, non-invasive rapid monitoring biochemical changes in complex matrices high sensitivity specificity. In this study, biofilms were grown treated...
We introduce a novel, facile, rapid, low-cost, highly reproducible, and power-free synthesizable fabrication method of paper-based silver nanoparticle (AgNP) immersed surface-enhanced Raman scattering (SERS) platform, known as the successive ionic layer absorption reaction (SILAR) method. The rough porous properties paper led to direct synthesis AgNPs on surface well in due capillary effects, resulting improved plasmon coupling with interparticles interlayers. proposed SERS platform showed...
Abstract Rapid and precise acute myocardial infarction (AMI) diagnosis is essential for preventing patient death. In addition, the complementary roles of creatine kinase muscle brain (CK‐MB) cardiac troponin I (cTnI) biomarkers in early late stages AMI demand their simultaneous detection, which difficult to implement using conventional fluorescence electrochemical technologies. Here, a nanotechnology‐based one‐stop immuno‐surface‐enhanced Raman scattering (SERS) detection platform reported...
To develop onsite applicable cancer diagnosis technologies, a noninvasive human biofluid detection method with high sensitivity and specificity is required, available for classifying from the normal group. Herein, three-dimensional evolutionary gold nanoarchitecture (3D-EGN) developed by forming Au nanosponge (AuS) on 96-well plate, followed decoration of nanoparticles (AuNPs) evolved nanolamination (AuNL) high-throughput urine sensing in liquid phase. The 3D-EGN exhibits not only strong...
Several fabrication methods have been developed for label-free detection in various fields. However, fabricating high-density and highly ordered nanoscale architectures by using soluble processes remains a challenge. Herein, we report biosensing platform that integrates deep learning with surface-enhanced Raman scattering (SERS), featuring large-area, close-packed three-dimensional (3D) of molybdenum disulfide (MoS2)-assisted gold nanoparticles (AuNPs) the on-site screening coronavirus...
We introduce a label-free biosensing cellulose strip sensor with surface-enhanced Raman spectroscopy (SERS)-encoded bimetallic core@shell nanoparticles. Bimetallic nanoparticles consisting of synthesis core Ag (AgNP) and shell gold (AuNPs) were fabricated on substrate by two-stage successive ionic layer absorption reaction (SILAR) techniques. The nanoparticle-enhanced localized surface plasmon resonance (LSPR) effects theoretically verified computational calculations finite element models...
Gold-decorated, vertically grown ZnO nanorods (NRs) on a flexible graphite sheet (Au/ZnONRs/G) were developed for surface-enhanced Raman scattering (SERS)-based biosensing to identify trace amounts of human aqueous humors. This Au/ZnONRs/G SERS-functionalized sensor was fabricated via two steps: hydrothermal synthesis-induced growth NRs sheets nanostructure fabrication, followed by e-beam evaporator-induced gold metallization ZnONRs/G SERS functionalization. The thickness the Au layer and...
We introduce a surface-enhanced Raman scattering (SERS)-functionalized, gold nanoparticle (GNP)-deposited paper strip capable of label-free biofluid sensing for the early detection infectious eye diseases. The GNP biosensing was fabricated by direct synthesis and deposition GNPs on wax-divided hydrophilic areas permeable porous substrate through facile, power-free synthesizable, highly reproducible successive ionic layer absorption reaction (SILAR) technique. To maximize localized surface...
Cell culture and polymerase chain reaction are currently regarded as the gold standard for adenoviral conjunctivitis diagnosis. They maximize sensitivity specificity but require several days to 3 weeks get results. The aim of this study is determine potential Raman spectroscopy a stand-alone analytical tool clinical diagnosis using human tear fluids. A drop-coating deposition surface enhanced scattering (DCD-SERS) method was identified most effective proteomic analysis in biofluids. proposed...