- EEG and Brain-Computer Interfaces
- Neural and Behavioral Psychology Studies
- Motor Control and Adaptation
- Neural dynamics and brain function
- Transcranial Magnetic Stimulation Studies
- Muscle activation and electromyography studies
- Medical Imaging Techniques and Applications
- Functional Brain Connectivity Studies
- Radiation Dose and Imaging
- Multisensory perception and integration
- Advanced X-ray and CT Imaging
- Neuroscience and Music Perception
- Digital Radiography and Breast Imaging
- Tactile and Sensory Interactions
- Visual perception and processing mechanisms
- Glaucoma and retinal disorders
- Nuclear and radioactivity studies
- Graphite, nuclear technology, radiation studies
- Ocular Surface and Contact Lens
- Neurological disorders and treatments
- Advanced MRI Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Ocular Infections and Treatments
- Olfactory and Sensory Function Studies
- Hearing Loss and Rehabilitation
National Institute for Physiological Sciences
2012-2024
Aichi Developmental Disability Center
2021-2024
Shiga University of Medical Science Hospital
2009-2023
National Institutes of Natural Sciences
2008-2022
University of Miyazaki
2019-2022
Shiga University of Medical Science
1997-2018
The Graduate University for Advanced Studies, SOKENDAI
2017-2018
Nagoya Institute of Technology
2017
Senju Pharmaceutical (Japan)
2007-2016
Nagasaki University
2010-2014
Abstract The sequence effect (SE) in Parkinson's disease (PD) is progressive slowing of sequential movements. It a feature bradykinesia, but separate from general slowness without deterioration over time. commonly seen PD, its physiology unclear. We measured and the SE separately with computer‐based, modified Purdue pegboard 11 patients advanced PD. conducted placebo‐controlled, four‐way crossover study to learn whether levodopa repetitive transcranial magnetic stimulation (rTMS) could...
Abstract Objective . Electroencephalograms (EEGs) are often used to monitor brain activity. Several source localization methods have been proposed estimate the location of activity corresponding EEG readings. However, only a few studies evaluated accuracy from measured using personalized head models in millimeter resolution. In this study, based on volume conductor analysis high-resolution human model constructed magnetic resonance images, finite difference method was solve forward problem...
To investigate the long-latency activities common to all sensory modalities, electroencephalographic responses auditory (1000 Hz pure tone), tactile (electrical stimulation index finger), visual (simple figure of a star), and noxious (intra-epidermal electrical dorsum hand) stimuli were recorded from 27 scalp electrodes in 14 healthy volunteers. Results source modeling showed multimodal activations anterior part cingulate cortex (ACC) hippocampal region (Hip). The activity ACC was biphasic....
The Japanese Society of Nuclear Medicine has recently published the consensus guidelines for pediatric nuclear medicine. This article is English version guidelines. Part 1 proposes dose optimization in medicine studies. 2 comprehensively discusses imaging techniques appropriate conduct procedures, considering characteristics children.
The neural mechanisms underlying unimodal spatial attention have long been studied, but the cortical processes cross-modal links remain a matter of debate. To reveal between vision and touch in attention, we recorded magnetoencephalographic (MEG) responses to electrocutaneous stimuli when subjects directed an or visual stimulus presented randomly left right space. Neural around bilateral sylvian fissures at 85 100 ms after were significantly enhanced by both touch-irrelevant -relevant...
Purpose To evaluate the pharmacokinetics and efficacy of topically applied nonsteroidal anti-inflammatory drugs (NSAIDs) in retinochoroidal tissues rabbits. Methods The cyclooxygenase (COX) inhibitory activity diclofenac, bromfenac, amfenac, an active metabolite nepafenac, were determined using human-derived COX-1 COX-2. Each three NSAIDs was to rabbits, after 0.5 8 hrs, concentration each drug aqueous humor measured by liquid chromatography-tandem mass spectrometry. repeated doses as is...
Abstract To elucidate the mechanisms underlying sensorimotor integration, we investigated modulation in primary (SI) and secondary (SII) somatosensory cortices during preparatory period of a self‐initiated finger extension. Electrical stimulation right median nerve was applied continuously, while subjects performed extension were instructed not to pay attention stimulation. The divided into five sub‐periods from onset electromyogram 3000 ms before movement magnetoencephalogram signals...
We recorded cortical activities in response to the onset and offset of a pure tone long duration (LONG) train brief pulses with an interstimulus interval 50 ms (ISI-50 ms) or 100 (ISI-100 by use magnetoencephalograms 11 healthy volunteers clarify temporal spatial profiles auditory on- off-cortical response. Results showed that region around superior gyrus (STG) both hemispheres responded stimulus. The location source responsible for main activity (N1m) was not significantly different between...