- Bladder and Urothelial Cancer Treatments
- Prostate Cancer Diagnosis and Treatment
- Urological Disorders and Treatments
- Renal cell carcinoma treatment
- Prostate Cancer Treatment and Research
- Urinary and Genital Oncology Studies
- Urologic and reproductive health conditions
- Trauma and Emergency Care Studies
- Ureteral procedures and complications
- Renal and Vascular Pathologies
- Renal and related cancers
- Smoking Behavior and Cessation
- Abdominal Trauma and Injuries
- Pediatric Urology and Nephrology Studies
- Genital Health and Disease
- Pelvic and Acetabular Injuries
- MRI in cancer diagnosis
- Nutritional Studies and Diet
- Organ Donation and Transplantation
- Cancer Risks and Factors
- Kidney Stones and Urolithiasis Treatments
- Global Cancer Incidence and Screening
- Multiple and Secondary Primary Cancers
- Cancer Immunotherapy and Biomarkers
- Anatomy and Medical Technology
University of North Carolina at Chapel Hill
2019-2025
UNC Lineberger Comprehensive Cancer Center
2019-2025
The Urology Center of Colorado
2024
Bladder Cancer Advocacy Network
2023
Cornell University
2023
Johns Hopkins University
2023
Sidney Kimmel Comprehensive Cancer Center
2023
Johns Hopkins Medicine
2023
University of North Carolina Health Care
2020-2023
University of North Carolina System
2023
We update the prior standard operating procedure for magnetic resonance imaging of prostate, and summarize available data about technique clinical use diagnosis management prostate cancer. This includes practical recommendations on screening, diagnosis, staging, treatment surveillance
To evaluate the safety and efficacy of gemcitabine cisplatin in combination with immune checkpoint inhibitor pembrolizumab as neoadjuvant therapy before radical cystectomy (RC) muscle-invasive bladder cancer.
BackgroundPatients with Bacillus Calmette–Guérin (BCG)–unresponsive non–muscle-invasive bladder cancer (NMIBC) have limited treatment options. The immune cell–activating interleukin-15 (IL-15) superagonist Nogapendekin alfa inbakicept (NAI), also known as N-803, may act synergistically BCG to elicit durable complete responses (CRs) in this patient population.MethodsIn open-label, multicenter study, patients BCG-unresponsive carcinoma situ (CIS) or without Ta/T1 papillary disease were treated...
Background: Pelvic fractures from blunt force trauma place the bladder and urethra at risk for injury, often resulting in significant complications. We sought to compare morbidity, mortality, health care resource utilization patients with without genitourinary injuries (GUI) associated pelvic fractures. Methods: In this retrospective study of fractures, incidence GUI, initial emergency department data, mechanism utilization, injuries, discharge disposition, mortality were investigated using...
To evaluate the cancer detection rates for men undergoing 12-core systematic prostate biopsy with negative prebiopsy multiparametric magnetic resonance imaging (mpMRI) results.Clinical data from consecutive who had undergone 3T mpMRI December 2011 to August 2014 were reviewed an institutional review board-approved prospective database. Men prebiospy results (negMRI) before identified present analysis. Clinical features, and predictive values summarized.Seventy five negMRI underwent during...
While magnetic resonance imaging-ultrasound fusion targeted biopsy allows for improved detection of clinically significant prostate cancer, a concerning amount disease is still missed. We hypothesized that number these misses are due to the learning curve associated with biopsy. report results repeat in men continued suspicion cancer and institutional time.We analyzed records 1,813 biopsies prospectively acquired cohort who presented 4-year period. All were offered prebiopsy imaging assigned...
With the significant downward size and stage migration of localized kidney cancers, management options for small cancers have expanded evolved.To describe trends outcomes in first decade new millennium.Surveillance, Epidemiology, End Results (SEER) cancer registry data linked to Medicare claims were used identify patients 66 years or older with a pathologically confirmed (<4 cm) diagnosed between January 1, 2001, December 31, 2009; analysis was performed February 2014, 2014. Multivariable...
We evaluated the discordance between ureteroscopic biopsy and surgical pathology findings for grading staging upper tract urothelial carcinoma. also sought to establish preoperative predictors of aggressive tumors.We retrospectively reviewed records 314 patients who underwent followed by management carcinoma from 2000 2016 at a total 3 institutions. Our primary outcomes were muscle invasive (pT2 or greater) disease upgrading clinical low grade tumors pathological high grade.At 61% had 21%...
Cigarette smoking is a known risk factor for bladder cancer. How urologists address cessation among patients with cancer not well-known. We assessed the practice patterns of American regarding assistance cancer.A questionnaire was sent to 1,821 in 2008 Urological Association membership directory. Responses were summarized frequency and percent. Statistical comparison made using chi-square tests. Multiple logistic regression used detect significant predictors providing assistance.Responses...