A5072780935- Stress Responses and Cortisol
- Tryptophan and brain disorders
- Neuroendocrine regulation and behavior
- Neuroscience and Neuropharmacology Research
- Memory and Neural Mechanisms
- Hormonal Regulation and Hypertension
- Neurotransmitter Receptor Influence on Behavior
- Animal Behavior and Welfare Studies
- Child and Adolescent Psychosocial and Emotional Development
University of Indianapolis
2020
Indiana University – Purdue University Indianapolis
2019-2020
Indiana University Bloomington
2014-2019
Prolonged or repeated exposure to stress increases risk for a variety of psychological disorders, many which are marked by dysfunction corticolimbic brain regions. Notably, women more likely than men be diagnosed with these especially when onset symptoms follows stressful life events. Using rodent models, investigators have recently begun elucidate sex-specific changes in the and behavior that occur immediately following chronic stress. However, little is known regarding lasting sequelae...
Dysfunction in corticolimbic circuits that mediate the extinction of learned fear responses is thought to underlie perseveration stress-related psychopathologies, including post-traumatic stress disorder. Chronic produces dendritic hypertrophy basolateral amygdala (BLA) and hypotrophy medial prefrontal cortex, whereas acute leads both BLA prelimbic cortex. Additionally, chronic impair retrieval. Here, we examined effects a single elevated platform on learning morphology infralimbic region...
Adolescence is an important period for HPA axis development and synapse maturation reorganization in the prefrontal cortex (PFC). Thus, stress during adolescence could alter stress-sensitive brain regions such as PFC may impact of future stressors on these regions. Given that women are more susceptible to many stress-linked psychological disorders which dysfunction implicated, this increased vulnerability emerges adolescence, time have sex-dependent effects. Therefore, we investigated...
Background Stress triggers alcohol use and relapse to drinking, with different effects by sex. Women are more susceptible stress‐related misuse, most stressors in rodents produce sexually divergent effects. Female particularly sensitive the stress produced solitary housing, yet impact of housing conditions on establishment, escalation, post‐abstinence potentiation intermittent access drinking male female rats, interaction these factors history not well described. Methods Male ( n = 62) 64)...