- Cutaneous lymphoproliferative disorders research
- Cutaneous Melanoma Detection and Management
- Hidradenitis Suppurativa and Treatments
- Cancer and Skin Lesions
- Nail Diseases and Treatments
- Dermatology and Skin Diseases
- Autoimmune Bullous Skin Diseases
- Chemotherapy-related skin toxicity
- Urticaria and Related Conditions
- Colorectal and Anal Carcinomas
- Herpesvirus Infections and Treatments
- Dermatological and Skeletal Disorders
- Autoimmune and Inflammatory Disorders
- Sarcoma Diagnosis and Treatment
- Genetic and rare skin diseases.
- Contact Dermatitis and Allergies
- Nonmelanoma Skin Cancer Studies
- Allergic Rhinitis and Sensitization
- Soft tissue tumors and treatment
- Asthma and respiratory diseases
- Anorectal Disease Treatments and Outcomes
- Poxvirus research and outbreaks
- Drug-Induced Adverse Reactions
- Cancer Diagnosis and Treatment
- Vascular Tumors and Angiosarcomas
Hospital Universitario Puerta de Hierro Majadahonda
2016-2025
Hospital Universitario de Gran Canaria Doctor Negrín
2024
Universidad Autónoma de Madrid
2007-2022
Centro Nacional de Microbiologia
2016
Comunidad de Madrid
2014
Hospital Clínico San Carlos
1994-1997
To support standardization for performing dermatologic ultrasound examinations.An international working group, called DERMUS (Dermatologic Ultrasound), was formed, composed of physicians who have been on a regular basis and publishing in peer-reviewed articles ultrasound. A questionnaire 5 critical issues about performance the examinations prepared distributed by e-mail. The areas discussion included technical aspects, main application, minimum number per year required assessing competence,...
HSV-1 establishes life-long latency that can result in clinical relapses or asymptomatic virus shedding. Although virtually all adults have been exposed to HSV-1, the course varies remarkably. Genetic host variability could be related this diversity. In study, we analyzed contribution of gene families chromosomes 1, 6, 12, and 19, which encode key regulators innate adaptive immunity, a cohort 302 individuals. Class I class II alleles HLA system, copy-number variation NK cell receptor genes...
Abstract Dermatologic ultrasound is a recent application of for the evaluation healthy skin and appendages their diseases. Although scientific literature regarding this still not sufficient evidence-based guidelines, general recommendations issued by societies are necessary. The EFSUMB (European Federation Societies Ultrasound in Medicine Biology) steering committee dermatologic has developed series consensus position statements main fields (technical requirement, normal appendages,...
BACKGROUND Staging and monitoring of patients with hidradenitis suppurativa (HS) have been traditionally based on clinical findings. However, the physical examination may show important limitations because its poor sensitivity for differentiating between different lesion subtypes, low to define disease's activity. OBJECTIVE To develop a consensus ultrasound (US) report that could summarize relevant anatomical characteristics staging considering experience radiologists dermatologists working...
Proposal for an Assessment TrainingProgram in Dermatologic Ultrasound by the DERMUS Group ermatologic ultrasound has been growing rapidly line with development of more potent machines and highfrequency probes.][3][4][5][6] To date, several training programs other areas have reported, such as musculoskeletal, [7][8][9][10][11] emergency, 12-14 cardiology, 15 anesthesiology 16 fields.Nevertheless, dermatologic a new application still lacks international formal or accreditation.Thus, increasing...
Numerous studies have investigated the association that exists between genetic variants and efficacy profile of biologic therapies for management psoriasis. However, as far we know, data on this brodalumab are lacking in currently available scientific literature. To analyze 180 polymorphisms with an optimal response to real-world clinical practice. A total 119 patients plaque psoriasis a 24-regimen recruited from 11 Spanish hospitals were genotyped polymorphisms. Optimal was evaluated...
Abstract Herpes simplex virus type 1 (HSV‐1) causes lifelong latent infections in most humans. Periodical reactivations from latency the neurons of sensitive ganglia lead to transport mucocutaneous regions and productive replication, which results recurrent inflammatory herpetic lesions or asymptomatic shedding. The medical consequences such frequency recurrences vary greatly different subjects. Furthermore, many infected individuals never suffer manifestations disease, even when exposed...
Deep-learning algorithms (DLAs) have been used in artificial intelligence aided ultrasonography diagnosis of thyroid and breast lesions. However, its use has not described the case dermatologic ultrasound Our purpose was to train a DLA discriminate benign form malignant lesions images.We trained prebuilt neural network architecture (EfficientNet B4) commercial platform (Peltarion, Stockholm, Sweden) with 235 color Doppler images both excised histologically confirmed skin (84.3% training,...
Objectives Basal cell carcinoma (BCC) is the most common dermatologic malignant skin cancer. Infiltrative histologic variants are more aggressive and require wider surgical margins or Mohs surgery, in contrast with noninfiltrative variants, which commonly treated standard excision. Elastography has not been used to date differentiate between of BCC. The purpose this study was infiltrative from BCCs on elastography. Methods A total 31 facial were studied. Preoperatively, color Doppler...
An 18‐year‐old female patient with acute myelogenous leukemia (AML) M2 was treated between March and June 1998 idarubicin, cytarabine, busulfan cyclophosphamide. In 1998, an autologous hematopoietic peripheral blood stem cell transplant performed. The asymptomatic without treatment until January 1999, when a relapse of AML observed. the waiting for another allogenic transplantation, she presented to Department Dermatology, Clínica Universitaria Puerta de Hierro, Madrid, onset few days...
Recent years have witnessed an increase in the use of ultrasound imaging skin field dermatology, as technique reveals details vessels and other structures that cannot be detected on physical examination. Extradigital glomus tumors are rarely seen clinical practice can pose a diagnostic challenge for dermatologists. We report 4 patients with suspicion extradigital tumor 1 patient subungual tumor. All 5 underwent examination B mode color pulsed-wave Doppler prior to surgical excision...
Background: High Frequency Ultrasonography (HFUS) is a rapid, reliable, and effective diagnostic technique that has become progressively employed within the past years among dermatologists. Objective: To describe use of HFUS dermatology departments in Spain. Methods: An observational, cross-sectional descriptive study was conducted 23 at Spanish public hospitals. Study data collected during 10 working days. Results: Fifty dermatologists from 11 regions participated study; 659 procedures were...
Atopic dermatitis predisposes to skin infections, and on the other hand, some therapies used for atopic may worsen viral infections whose lesions be more diffuse resistant treatment. The authors present a patient with severe disseminated molluscum contagiosum infection. did not clear topical treatment, it worsened her even more, so started treatment dupilumab. After two months, patient's went into clinical remission there was resolution of infection no recurrence at 12-month follow-up....
Although the diagnosis of tinea capitis is mainly microbiological, risk evolution towards cicatricial alopecia in most severe cases requires empirical treatment based on physical examination and complementary examinations.
Abstract Detecting the association of genetic variants to response biological therapy represents an important advance in developing a personalized therapy. The aim this work was study polymorphisms with optimal tildrakizumab patients psoriasis real‐life clinical practice. Ninety plaque recruited from—Spanish hospitals receiving for at least 24 weeks were genotyped 180 polymorphisms. Optimal evaluated by absolute PASI ≤1 6 and 12 months. Polymorphisms corrected weight disease duration FDR...