A5025967702- Stress Responses and Cortisol
- Pain Management and Opioid Use
- Mental Health Research Topics
- Mindfulness and Compassion Interventions
- Psychological Well-being and Life Satisfaction
- Family Support in Illness
- Optimism, Hope, and Well-being
- COVID-19 and Mental Health
- Cultural Differences and Values
- Cancer survivorship and care
- Decision-Making and Behavioral Economics
- Psychosomatic Disorders and Their Treatments
- Attachment and Relationship Dynamics
- Cancer Immunotherapy and Biomarkers
- Memory Processes and Influences
- Face Recognition and Perception
- Cannabis and Cannabinoid Research
- Film in Education and Therapy
- Racial and Ethnic Identity Research
- Bullying, Victimization, and Aggression
- Brain Metastases and Treatment
- Emotion and Mood Recognition
- Protein Degradation and Inhibitors
- Media Influence and Health
- Spacecraft Design and Technology
University of California, Irvine
2017-2024
National Cancer Institute
2020-2024
National Institutes of Health
2024
Florida College
2024
University of Florida
2023-2024
Johnson Space Center
2007
Simpatía, a term that captures the tendency to prefer and create social interactions characterized by warmth emotional positivity while also avoiding conflict and/or overt negativity, is cultural factor relevant Latinos. The goal of this article was develop scale measures value.A self-report measure simpatía developed administered combined sample Latinos (N = 296) drawn from 3 larger studies. scale's structure explored, its internal consistency validity were tested.Exploratory analysis...
Abstract Racial and ethnic disparities in pain management pose major challenges to equitable cancer care delivery. These are driven by complex interactions between patient-, provider-, system-related factors that resist reductionistic solutions require innovative, holistic approaches. On September 19, 2022, the Society for Integrative Oncology American of Clinical published a joint guideline provide evidence-based recommendations on integrative medicine management. medicine, which combines...
Abstract Cancer-related pain affects a large proportion of all patients with cancer yet remains inadequately managed, particularly among from certain racialized backgrounds. Recently, there has been increased research and clinical interest in the use medical cannabis for management, including its potential to ameliorate race-based disparities control. Although is not currently US Food Drug Administration–approved treatment option cancer-related pain, many oncologists discuss recommend their...
Importance Racial disparities in prostate cancer are likely the result of complex relationships between both socioeconomic and environmental factors captured by neighborhood environment genetic factors, including West African ancestry. However, few studies have examined combined role ancestry developing lethal cancer. Objective To examine interactions deprivation modifying risk mortality. Design, Setting, Participants This case-control study was conducted Greater Baltimore area. included men...
Objectives/Goals: The NIH Common Fund launched Community Partnerships to Advance Science for Society (ComPASS) study ways reduce health disparities by addressing underlying structural factors within communities. ComPASS was designed community organizations lead research that addresses needs. Methods/Study Population: awarded five equity hubs (Hubs) provide specialized technical support projects led organizations. Expertise provided the Hubs community-led will focus on specific facets of...
Abstract Objectives Cancer‐related pain in children is prevalent and undermanaged. Mobile health (mHealth) applications provide a promising avenue to address the gap management with cancer. Pain Buddy multicomponent mHealth application developed manage cancer‐related children. The goal of this paper present preliminary efficacy data impact on children's severity frequency. Methods In randomized controlled trial over 60 days, ( N = 48) reported daily tablet while receiving usual care. Those...
Abstract Background Communities and researchers have called for a paradigm shift from describing health disparities to equity research agenda that addresses structural drivers. Therefore, we examined whether the cancer survivorship portfolio has made this shift. Methods We identified grants focused on populations experiencing National Institutes of Health (NIH) Cancer Survivorship Research Portfolio (N = 724), Fiscal Years 2017–2022. Grant characteristics were abstracted, drivers mapped onto...
The Advanced NASA Technology Architecture for Exploration Studies (ANTARES) simulation is the primary tool being used requirements assessment of Orion spacecraft by Guidance Navigation and Control (GN&C) teams at Johnson Space Center (JSC). ANTARES a collection packages model libraries that are assembled executed Trick environment. Currently, design assessment, performance analysis, validation, Hardware In Loop (HWIL) Human (HIL) testing.
Positive and negative affect have been shown to implications for hormones like cortisol but how moment changes in (i.e., variability) influence secretion is less well understood. Additionally, context characteristics such as mean stress may the association between variability output. In current study, we examined affect, stress, data from 113 participants (age range = 25-63, M 35.63, SD 11.34; 29% male; 42% White/Caucasian, 37% Asian or Pacific Islander, 13% Hispanic/Latino, 4% Black/African...
Smiling has been previously shown to improve stress responses. We replicated and expanded this work by testing whether smiling helps with a potent real-world stressor: vaccination-like needle injection. also extended past research examining grimacing, facial expression known naturally occur during pain one that shares some of the same action units as smiling. Participants (n = 231; [M]age 19.2) were randomized hold either Duchenne smile, non-Duchenne grimace, or neutral while receiving...
Researchers typically assume that all forms of positive affect (PA) are equally beneficial for attenuating the physiological stress response. We tested whether this association is more nuanced by examining role arousal level PA on responses to acute pain. Participants (N = 283, 75.6% female, Mage 20.6) were randomized a low, mid, or high (calm, happy, and excited, respectively) induction condition neutral control then completed an pain-inducing cold pressor task. Sympathetic parasympathetic...
Abstract Background: Although recent advances in immunotherapy for metastatic melanoma have transformed the treatment paradigm a disease that once carried grim prognosis, nearly 50% of patients fail to reach complete response immune checkpoint blockade (ICB) due multiple mechanisms tumor-induced resistance. These challenges are amplified CNS tumor microenvironment (TME) where brain (MBM) demonstrates diminished clinical benefit ICB treatment. A deeper understanding these required improve...
Abstract This review assesses laser-based diagnostic modalities for intraoperative tissue diagnosis in neurosurgical oncology, emphasizing their utility delineating tumor margins. Technologies such as optical coherence tomography, photoacoustic imaging, and confocal microscopy are scrutinized capability to enhance discernment of neoplastic versus healthy tissue. We discuss the technical advancements, limitations related depth penetration resolution, innovative approaches mitigate these...
Research has established the effects of romantic relationships on individuals' morbidity and mortality. However, interplay between relationship functioning, affective processes, health behaviors been relatively understudied. During COVID-19 pandemic, relational processes may influence novel such as social distancing masking.
Abstract Importance: Exposure to chronic stress have been implicated as a contributor disparities in cancer risk and outcomes. Yet, the biological mechanisms underlying their influence on tumor biology immune microenvironment remain poorly understood. Objective: To investigate genomic, transcriptomic, proteomic impact of multi-level stress-related measures (chronic stress, racial ethnic discrimination, inadequate social support, neighborhood deprivation) local systemic environment White...
<h3>Background</h3> Head and neck squamous cell carcinoma (HNSCC) is one of the most frequent cancers worldwide. Different approaches are applied to treat cancer. Recently, several therapies were approved for treatment head cancers, some at clinical trial stage.<sup>1–4</sup> The aim this study was develop a comprehensive quantitative systems pharmacology (QSP) model HNSCC that captures key cellular molecular processes allows explore combination therapies. <h3>Methods</h3> QSP includes...