A5101514044- Sleep and related disorders
- Acupuncture Treatment Research Studies
- Sleep and Wakefulness Research
- Complementary and Alternative Medicine Studies
- Medical Research and Treatments
- Healthcare and Venom Research
- Traditional Chinese Medicine Studies
- Eosinophilic Esophagitis
- Receptor Mechanisms and Signaling
- Esophageal and GI Pathology
- Long-Term Effects of COVID-19
- Circadian rhythm and melatonin
- Mollusks and Parasites Studies
- COVID-19 and Mental Health
- Neurotransmitter Receptor Influence on Behavior
- Protein Hydrolysis and Bioactive Peptides
- Infant Health and Development
- Neuroscience and Neuropharmacology Research
- ATP Synthase and ATPases Research
- Glutathione Transferases and Polymorphisms
- T-cell and B-cell Immunology
- Gastrointestinal motility and disorders
- Pharmacological Receptor Mechanisms and Effects
- Phytochemistry and Biological Activities
- Biocrusts and Microbial Ecology
Nanjing University of Chinese Medicine
2017-2025
Jiangsu Province Hospital
2018-2025
Tianjin University
2024
Nanjing Agricultural University
2023-2024
Liaocheng People's Hospital
2024
People's Hospital of Shiyan
2017
Kai Biotech (South Korea)
2015
Shandong University
2011
Princeton University
2007
Baylor College of Medicine
1994
There reportedly exists a significant comorbidity between insomnia and neurodegenerative diseases, such as Alzheimer's disease (AD) Parkinson's (PD), indicative of potential link to serum metabolic dysregulation. To elucidate shared pathophysiological mechanisms AD/PD, we performed comprehensive two-sample Mendelian randomization (MR) analyses, investigating 1,400 characteristics for their causal relationships with the risks insomnia, AD, widely defined AD (WDAD), PD. We employed publicly...
Depression and insomnia are common categories of physical mental medicine, which causative each other often occur as co-morbidities, causing a huge health economic burden. Acupuncture treatment in co-morbidity mild-moderate depression shows better clinical efficacy, with multi-target, multi-pathway, multi-dimensional characteristics. However, the efficacy effect mechanism acupuncture parameters have not been clearly determined, therefore, this paper systematically describes possible...
Insomnia is a well-recognized clinical sleep disorder in the adult population. It has been established that acupuncture effects treatment of insomnia; however, research on underlying neural circuits involved these limited.The modified multiple platform method (MMPM) was used to establish rat model chronic deprivation (CSD). Forty rats were randomly divided into control (Con) group, (untreated) CSD electroacupuncture-treated group (CSD + EA) and estazolam-treated Estazolam group) with n = 10...
Abstract Background Acupuncture, as an important component of traditional Chinese medicine (TCM), has been widely applied in the treatment chronic insomnia China, while there is no clinical study related to its therapeutic mechanism. Methods/design A single-center, single-blind, randomized, placebo-controlled trial will be conducted at Jiangsu Hospital Traditional Medicine. total 60 patients registered. Eligible participants randomly divided into acupuncture group and sham ( n = 30 cases...
Joyce E. Longcorea* , Shan Qinb D. Rabern Simmonsc & Timothy Y. Jamesc a School of Biology and Ecology, University Maine, Orono, Maine 04469-5722b Phycological LLC, Gilbert, Arizona 85297-1977c Department Ecology Evolutionary Biology, Michigan, Ann Arbor, Michigan 48109-1085
Abstract Introduction The incidence of insomnia is getting higher and higher. Long-term seriously affects people’s health. Drug use usually accompanied with adverse events. Both acupuncture cognitive behavioral therapy for (CBT-I) have been proven to be safe effective non-pharmacological treatments insomnia. As the insomniacs’ bad sleep behavior wrong cognition not effectively corrected, has a quick effect, high patient compliance but unstable long-term efficacy, while CBT-I complex,...
Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder characterized by abdominal pain and change of habit without organic disease. A global perspective given the World Gastroenterology Organization (WGO) points out that IBS can impact quality an individual's daily life, cause socioeconomic problems potentially impair patient-physician relationship. It remains problem to treat due complicated pathophysiology. Acupuncture alternative therapy recommended for IBS. The aim this...
To develop a HPLC method quantitative for simultaneous determination of chlorogenic acid, 1, 5-dicaffeoylquinic isochlorogenic acid A, C, luteolin-7-O-beta-D-glucoside and apigenin-7-O-beta-D-glucoside in Chrysanthemum morifolium Ramat.A Phenomenex Gemini-NX C18 column (4.6 mm x 250 mm, 5 microm) was used with CH3 OH 0.4% H3PO4 as mobile phases. The flow rate 1 mL min(-1), the temperature 25 degrees detection wavelength set at 350 nm.The 6 active components were baseline separation....
The aim of this study was to investigate the functional abnormalities between nucleus accumbens (NAc) and whole brain in individuals with Insomnia Disorder (ID) using resting-state magnetic resonance imaging (fMRI). Additionally, aimed explore underlying neural mechanisms ID. We enrolled 18 participants ID 16 normal controls (NC). Resting-state connectivity (FC) NAc voxels calculated compared two groups identify differential region. Receiver operating characteristic (ROC) curve analysis...
To observe the effect of acupuncture on expression transforming growth factor-β1(TGF-β1) in lacrimal gland rabbits with dry eye, so as to explore its underlying mechanism improving eye.Healthy male New Zealand were randomly assigned 5 groups (n=6 each group), namely, blank group, model western medicine group and sham group. The dye eye rabbit was estabilished by subcutaneous injection Scopolamine Hydrobromide solution for 21 days. After modeling, treated Flumirone drops their eyes 3 times a...
Background Previous studies show that insomnia and hypertension are closely related. Currently, intervention for with has become a research hotspot. Acupuncture, as representative non-pharmaceutical therapy of traditional Chinese medicine (TCM), been widely used in improving hypertension. However, there few clinical on acupuncture insomnia. Methods A single-center, subject-and-assessor-blind, randomized, sham-controlled trial designed study to be conducted Jiangsu Province Hospital Medicine....
Currently, few studies have demonstrated the relationship between total serum IgE (T-IgE) and acute exacerbation chronic obstructive pulmonary disease (AECOPD). In this study, T-IgE in AECOPD patients were investigated jointly analyzed with clinical characteristics. hospitalized from July 2018 to 2019 included study. patient cohort, information was investigated. Routine blood tests, C-reactive protein levels of determined along gas analysis. The length hospital stays, mechanical ventilation...
Methamphetamine (METH) withdrawal anxiety symptom and relapse have been significant challenges for clinical practice, however, the underlying neuronal basis remains unclear.Our recent research has identified a specific subpopulation of choline acetyltransferase (ChAT + ) neurons localized in external lateral portion parabrachial nucleus (eLPB ChAT ), which modulates METH primed-reinstatement conditioned place preference (CPP).Here, anatomical structures functional roles eLPB projections...
To observe the effect of electroacupuncture (EA) on sleep quality and electroencephalogram (EEG) signal in patients with chronic insomnia to explore its mechanism.