Implantable loop recorders (ILR) allow prolonged cardiac rhythm monitoring and improved diagnostic yield in syncope patients. Predictive factors for pacemaker (PM) implantation the ILR population with unexplained have not been adequately investigated. In this single center, retrospective, observational study we investigated that predict PM population.We retrospectively analyzed our database of patients aged over 18 years who underwent between January 2009 June 2013. Patient case notes were...

Background Efforts to maintain sinus rhythm in patients with persistent atrial fibrillation (PsAF) remain challenging, suboptimal long-term outcomes. Methods All undergoing convergent PsAF ablation at our centre were retrospectively analysed. The Atricure Epi-Sense® system was used perform surgical radiofrequency of the LA posterior wall followed by endocardial ablation. Results A total 24 underwent ablation, and 21 (84%) them male a median age 63. Twelve (50%) obese. In total, 71% had...

There is growing interest in detecting paroxysmal atrial fibrillation (PAF) to identify patients at high risk of thromboembolic stroke. The implantable loop recorder (ILR) emerging as a powerful new tool the diagnosis PAF. Widespread implantation has significant cost implications and their use must be targeted those most risk.We retrospectively studied population 200 adult who underwent ILR for investigation syncope or palpitations. Clinical data, baseline electrocardiogram (ECG)...

Recent NICE guidance has highlighted the importance of appropriate and safe intravenous fluid use. We aimed to improve quality out hours prescription in a Bristol hospital by ensuring that indications cautions for therapy were clearly documented at time initiation. Time-pressured on-call doctors need quick access information regarding patients' care. A "fluid plan" allows undertake more informed assessment patient's balance, leading safer prescriptions. Our ideal was 100% prescriptions be...

<h3>Abstract</h3> Hospital medicine in the UK is under unprecedented pressure, with increasing demand on physicians as well challenges recruiting new doctors into physicianly specialties. We sought to assess prevalence of afternoon ward round and its effect those undertaking them. sampled each hospital within our postgraduate region, surveying junior working inpatient medical wards. surveyed roughly two-thirds eligible doctors, ­finding that 30% juniors had some commitment, varying...

Direct current cardioversion (DCCV) is a safe and effective treatment for recent-onset atrial fibrillation (AF) or flutter when performed in the emergency department (ED), it can provide an excellent option patients as well reducing unnecessary hospital admissions healthcare costs. However, appropriate periprocedural anticoagulation absolutely essential to reduce risk of adverse outcomes, chiefly thromboembolic stroke. Our intention was 100% undergoing DCCV ED receive anticoagulation.We...

BackgroundAtrial-ventricular differences in voltage-gated Na+ currents might be exploited for atrial-selective antiarrhythmic drug action the suppression of atrial fibrillation without risk ventricular tachyarrhythmia. Eleclazine (GS-6615) is a putative with properties similar to prototypical channel blocker ranolazine that has been shown safe and well tolerated patients.ObjectiveThe present study investigated atrial-ventricular biophysical inhibition by eleclazine currents.MethodsThe fast...

A woman with recent personalized external aortic root support implant presented in cardiogenic shock bilateral coronary ostial occlusion and inflammation requiring emergency angioplasty. Subsequent computed tomography positron emission scanning demonstrated aortitis extensive adjacent to the mesh, first report of this important complication.

Abstract Introduction Cardiomyocytes in the pulmonary vein (PV) sleeves are a major source of ectopic activity driving atrial fibrillation (AF) and episodes AF patients more prevalent at night. While it is known that circadian clocks within heart regionally control 24-hour variation pacemaking ventricular repolarisation, mechanisms underlying nighttime preponderance unknown. Purpose This study addresses hypothesis rhythms exist pro-arrhythmic PV cardiomyocytes. Methods Male Wistar rats...

<h3>Introduction</h3> Atrial septal defects (ASD) often co-exist with atrial fibrillation (AF). Current thinking suggests AF burden may be improved by ASD closure and that catheter interventions should occur before to minimise procedural risks. There are few published studies investigating the natural history of or ablation outcomes in patients. Methods: We undertook a retrospective observational study all percutaneous procedures over 12-year period. Demographic data were collected. Patients...

<h3>Introduction</h3> The evidence base for rhythm control strategies in atrial fibrillation (AF) remain contentious. Synchronised DC cardioversion (DCCV) is a simple and accessible treatment option many centres. However, there little data to support its use as long-term strategy or regarding which groups benefit most from this strategy. <h3>Methods</h3> We collected AF cases across six-year period at busy district general hospital with nurse-led service. Demographic, echocardiographic...

Background Nearly 40% of the patients presenting with ST Elevation Myocardial Infarction (STEMI) have multivessel disease (MVD). Currently ESC and ACC/AHA guidelines recommend revascularization culprit artery only. 2 recent trials (PRAMI CVLPRIT) shown a superiority complete in-hospital revascularisation as compared to only treatment. Although mortality in groups were not significantly different but composite end point was, which was mainly driven by ischaemia.

Abstract Introduction Respiratory sinus arrhythmia (RSA) is the oscillation of heart rate in phase with ventilation and represents high frequency component variability. RSA prevalent young endurance-trained its loss considered a prognostic indicator for sudden cardiac death. The recapitulation improves function animal models failure1,2. However, precise mechanisms by which affects are unknown. Hypothesis: We examined hypothesis that isolated ventricular myocytes stimulus interval-dependence...

<h3>Background</h3> Traditionally, the presence of Q-waves on 12 lead ECG is considered a marker large and/or transmural myocardial infarction (MI). Late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) accurately identifies and extent has become gold standard for assessment viability. <h3>Aim</h3> To determine diagnostic accuracy to identify scarring as compared with CMR. <h3>Methods</h3> Data was collected 631 consecutive patients referred stress CMR suspected ischaemic...

Abstract Both investigators had personally experienced situations when they were let down by emergency suctioning equipment on the wards: due to either lack of, or operator inability use, equipment. Failings in suction have been highlighted a recent National Patient Safety Agency signal. We focused improving usability of cardiac arrest trolley suction: complex process involving turning small, hidden lever. produced three clearly visible bright labels which provided simple prompts operator....

The individual in our case was troubled with difficult to control arrhythmia the context of RYR2-mutation positive catecholaminergic polymorphic ventricular tachycardia (CPVT) despite medication. Recurrent implantable cardioverter defibrillator (ICD) shocks occurred for (VT) and fibrillation (VF) as well inappropriate a result rapidly conducted atrial (AF). Catheter ablation effective controlling these episodes AF. Despite left cardiac sympathetic denervation, subsequent ICD persisted....