About
Contact & Profiles
A5084318384
Research Areas
- Mitochondrial Function and Pathology
- Genetics, Aging, and Longevity in Model Organisms
- Metabolism and Genetic Disorders
- DNA Repair Mechanisms
- Epigenetics and DNA Methylation
- Genetic Neurodegenerative Diseases
- ATP Synthase and ATPases Research
Park Centre for Mental Health
2018-2024
The University of Queensland
2018-2024
10.1016/j.cmet.2024.07.020
article
EN
Cell Metabolism
2024-08-23
10.1038/s41556-023-01192-y
article
EN
Nature Cell Biology
2023-07-17
Abstract In virtually all eukaryotes, the mitochondrial genome (mitochondrial DNA, mtDNA) encodes proteins necessary for oxidative phosphorylation (OXPHOS) and RNA machinery required their synthesis inside mitochondria. Appropriate regulation of mtDNA copy number expression is essential ensuring correct stoichiometric formation OXPHOS complexes assembled from both nuclear- mtDNA-encoded subunits. The mechanisms are not completely understood but to organismal viability lifespan. Here, using...
10.1101/2023.03.27.534335
preprint
EN
bioRxiv (Cold Spring Harbor Laboratory)
2023-03-27
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