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Vahid Zarezade

ORCID: 0000-0003-3657-4041
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A5084204372
Research Areas
  • Computational Drug Discovery Methods
  • Synthesis and biological activity
  • Click Chemistry and Applications
  • Epigenetics and DNA Methylation
  • SARS-CoV-2 and COVID-19 Research
  • Estrogen and related hormone effects
  • Synthesis and Characterization of Heterocyclic Compounds
  • Histone Deacetylase Inhibitors Research
  • Protein Kinase Regulation and GTPase Signaling

Ahvaz Jundishapur University of Medical Sciences
 2021

 Computational investigation of novel farnesyltransferase inhibitors using 3D-QSAR pharmacophore modeling, virtual screening, molecular docking and molecular dynamics simulation studies: A new insight into cancer treatment
OPENALEX - Publications 
Arman Safavi Elaheh Sadat Ghodousi Mehdi Ghavamizadeh Mohamad Sabaghan Omid Azadbakht and 5 more Ali Veisi Hossein Babaei Zahra Nazeri Mehrnaz Karimi Darabi Vahid Zarezade

10.1016/j.molstruc.2021.130667 article EN Journal of Molecular Structure 2021-05-15
 The identification of novel inhibitors of human angiotensin-converting enzyme 2 and main protease of Sars-Cov-2: A combination of in silico methods for treatment of COVID-19
OPENALEX - Publications 
Vahid Zarezade Hamzeh Rezaei Ghodratollah Shakerinezhad Arman Safavi Zahra Nazeri and 5 more Ali Veisi Omid Azadbakht Mahdi Hatami Mohamad Sabaghan Zeinab Shajirat

10.1016/j.molstruc.2021.130409 article EN Journal of Molecular Structure 2021-04-06
 Unveiling Arformoterol as a potent LSD1 inhibitor for breast cancer treatment: A comprehensive study integrating 3D-QSAR pharmacophore modeling, molecular docking, molecular dynamics simulations and in vitro assays
OPENALEX - Publications 
Hamzeh Rezaei Vahid Zarezade Iraj Khodadadi Heidar Tavilani Hamid Tanzadehpanah and 1 more Jamshid Karimi

10.1016/j.ijbiomac.2023.129048 article EN International Journal of Biological Macromolecules 2023-12-28
 The Identification of Novel Inhibitors of Human Angiotensin-converting Enzyme 2 and Main Protease of Sars-Cov-2: A Combination of in silico Methods for Treatment of COVID-19
OPENALEX - Publications 
Vahid Zarezade Hamzeh Rezaei Ghodratollah Shakerinezhad Arman Safavi Zahra Nazeri and 6 more Ali Veisi Omid Azadbakht Mahdi Hatami Mohamad Sabaghan Zeinab Shajirat Maryam Zarghooni

The angiotensin-converting enzyme 2 (ACE2) and main protease (MPro), are the putative drug candidates for severe acute respiratory syndrome coronavirus (SARS-CoV-2). In this study, we performed 3D-QSAR pharmacophore modeling screened 1264479 ligands gathered from Pubchem Zinc databases. Following calculation of ADMET properties, molecular docking was carried out. Moreover, de novo ligand design performed. MD simulation then applied to survey behavior ligand-protein complexes. Furthermore,...

10.22541/au.164864364.49779563/v1 preprint EN Authorea (Authorea) 2022-03-30
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