A5079081230- Ocular Diseases and Behçet’s Syndrome
- Systemic Lupus Erythematosus Research
- Retinal Diseases and Treatments
- Autoimmune and Inflammatory Disorders Research
- S100 Proteins and Annexins
- Galectins and Cancer Biology
- Atherosclerosis and Cardiovascular Diseases
- Cell Adhesion Molecules Research
- Brucella: diagnosis, epidemiology, treatment
- Hormonal Regulation and Hypertension
- Vasculitis and related conditions
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Muscle and Compartmental Disorders
- Apelin-related biomedical research
- Neuroinflammation and Neurodegeneration Mechanisms
- Retinopathy of Prematurity Studies
- Retinal and Optic Conditions
- Peripheral Artery Disease Management
- Musculoskeletal synovial abnormalities and treatments
- Blood Coagulation and Thrombosis Mechanisms
- Angiogenesis and VEGF in Cancer
- Natural Antidiabetic Agents Studies
- Inflammatory Biomarkers in Disease Prognosis
- Cytomegalovirus and herpesvirus research
- Inflammasome and immune disorders
Diyarbakır Gazi Yaşargil Eğitim ve Araştırma Hastanesi
2025
Antalya Bilim University
2023-2024
Çanakkale Onsekiz Mart Üniversitesi
2020-2023
Fırat University
2006-2012
Michigan Science Center
2011
Elazığ Eğitim ve Araştırma Hastanesi
2011
Introduction/Objective. This study aimed to evaluate the relationship between changes in creatine kinase (CK) levels and need for dialysis patients with crush syndrome (CS). Methods. We conducted a retrospective analysis of CS who were admitted our hospital after earthquake from February May 2023. recorded demographic laboratory data divided them into two groups based on change CK within 48 hours. The compared mortality rates. Results. A total 84 injuries participated (41 males 43 females)....
To identify the effect of infliximab, cyclosporine A and recombinant IL-10 in experimental autoimmune uveitis.Sixty male rats were assigned to five groups 12 each. All (except control group) administered 30 microg retinal-S antigen intraperitoneally. On 14th day, after confirmation uveitis with histopathological study, daily injection was given treatment group physiological serum uveitis-induced placebo groups. In infliximab group, on 14th, 15th, 17th, 19th 21st days. three doses four hours...
Abstract Background: Rosacea is a chronic inflammatory skin disease. Previous studies have determined that IL-36, IL-37, and IL-38 may play role in the pathogenesis of various diseases. Aims Objectives: The present study aims to evaluate relationship these cytokines with rosacea. Materials Methods: A total 100 individuals, including 50 patients rosacea healthy controls, were included study. levels measured using ELISA method by taking serum samples from all participants. Results: mean...
Recent studies indicate that osteoprotegerin (OPG) acts as an important molecule in the development of vascular diseases. The aim present study was to examine association between serum OPG levels and Behcet's disease (BD). Materials methods: Twenty-five patients with BD 20 healthy control subjects, matched for age sex, were included this study. Serum determined using ELISA. Results: We found significantly higher than subjects (813.75 ± 11 vs. 655.56 17 pg/mL, P = 0.002). There no difference...
Brucellosis is significantly influenced by the interactions between causative Brucella bacteria and host immunity. Recently identified cytokines have been described for their immunomodulatory effects in numerous inflammatory, autoimmune infectious diseases. Some of them are new members cytokine superfamilies, including several IL-12 superfamily (IL-35, IL-39). The major purpose present study was to investigate role these infections. levels IL-35 IL-39 serum 40 acute chronic brucellosis...
Objective: To investigate the protective effect of recombinant human IL-11 (rhIL-11) administered in a systemic manner on retina tissue during ischemia/reperfusion (I/R) injury guinea pig model. Materials and Methods: An experimental study retinal I/R. Placebo, ischemia/sham, ischemia/rhIL-11 groups including five animals each were formed from male albino pigs. Retinal ischemia was induced by cannulating anterior chambers lifting bottle to height 205 cm for 90 Min sham groups. The...
Objective: Behcet's disease (BD) is a chronic, recurrent, inflammatory disease. CD19+CD5+ B cells are currently defined as B1 and they produce polyreactive antibodies. CD20+CD38 low can cause endothelial cell adhesion responsible for specific antibody synthesis. The aim of this study was to investigate the presence containing molecule, which plays role in differentiation activation. Moreover, ratio these BD patients also evaluated. Material Methods: In study, 20 healthy control subjects were...
INTRODUCTION Rosacea is a chronic inflammatory cutaneous disorder that usually occurs in adults between 20 and 50 years old.[1-3] The etiopathogenesis of rosacea poorly understood. Genetic predisposition, environmental triggers, immune dysregulation, reactions to microorganisms, neurovascular vascular dysfunction are the possible underlying factors. Various triggers known aggravate symptoms, such as ultraviolet exposure, diet, smoking, alcohol consumption, obesity, stress.[4-7] In addition,...
To investigate the peripheral blood levels of B and T lymphocyte attenuator (BTLA/CD272) on cells its role in Behçet disease (BD), to define inhibitory receptors BD. Materials methods: Included this study were 25 patients with BD 20 healthy control subjects, matched for age sex. Results: CD4+CD272+ (P < 0.001) CD3+CD272+ cell significantly higher (active remission) compared controls. However, there was no difference between active those remission terms cells, while active-phase phase 0.05)....
Abstract Diabetes mellitus (DM) is the most common chronic endocrine disorder. Although new drugs and administration techniques for diabetes were developed, nature of complications that occur chronically reduce patients’ quality life have not been entirely determined. In our study, 35 male rats used. A single dose 40 mg/kg streptozotocin was injected intraperitoneal into 28 rats, a total five groups formed. model performed by applying 40mg/kg STZ. established in subjects control citrate...