A5020679792- Malaria Research and Control
- Mosquito-borne diseases and control
- Computational Drug Discovery Methods
- Global Maternal and Child Health
- Neonatal Health and Biochemistry
- Digital Imaging for Blood Diseases
- Blood donation and transfusion practices
- HIV Research and Treatment
- Hemoglobinopathies and Related Disorders
- Methemoglobinemia and Tumor Lysis Syndrome
- HIV/AIDS drug development and treatment
- COVID-19 diagnosis using AI
- Endometriosis Research and Treatment
- Erythrocyte Function and Pathophysiology
- Genetics, Bioinformatics, and Biomedical Research
- Animal and Plant Science Education
- SARS-CoV-2 and COVID-19 Research
- Pregnancy and preeclampsia studies
- Endometrial and Cervical Cancer Treatments
- SARS-CoV-2 detection and testing
- HIV/AIDS Research and Interventions
- Animal Behavior and Reproduction
- Uterine Myomas and Treatments
- Parasites and Host Interactions
- Vector-borne infectious diseases
Wollega University
2023
Ethiopian Public Health Institute
2015-2022
Addis Ababa University
2016-2021
Dilla University
2016
Jimma University
2015
Background In Sub-Saharan African countries, including Ethiopia, malaria in pregnancy is a major public health threat which results significant morbidities and mortalities among pregnant women their fetuses. endemic areas, Plasmodium infections tend to remain asymptomatic yet causing problems like maternal anemia, low birth weight, premature births, still birth. This study was conducted determine the prevalence predictors of infection rural surroundings Arba Minch Town, Southern Ethiopia....
Malaria incidence has declined in Ethiopia the past 10 years. Current malaria diagnostic tests, including light microscopy and rapid antigen-detecting tests (RDTs) cannot reliably detect low-density infections. Studies have shown that nucleic acid amplification are highly sensitive specific detecting infection. This study took place with aim of evaluating performance multiplex real time PCR for diagnosis using patient samples collected from health facilities located at elimination targeted...
Background As per the WHO recommendation, development of resistance by P. falciparum to most artemisinin combination therapies (ACTs) triggered need for routine monitoring efficacy drugs every two years in all malaria endemic countries. Hence, this study was carried out assess therapeutic Artemether-Lumefantrine (Coartem®) treating uncomplicated malaria, after 9 its introduction Metehara, Eastern Ethiopia. Method This is part studies Federal Ministry Health Ethiopia, which were conducted...
Anemia during pregnancy is a well known medical condition most of the time under-recognized as it overshadowed by normal physiological pregnancy. This study aimed at determining prevalence and predictors anemia among pregnant women residing in rural surroundings Arbaminch Town, south Ethiopia.A cross-sectional community based was conducted between April June, 2013. A structured questionnaire used to collect socio-economic socio-demographic characteristics women. Hematocrit (HCT) level...
Anopheles mosquitoes are of great importance to human health. A number studies have shown that midgut and salivary gland microflora an impact on malaria parasite burden through colonization mechanisms, involving either direct Plasmodium microbiota interaction or bacterial-mediated induction mosquito immune response. The objective this study was isolate identify the from glands species. total 20 pools (ten per pool) insectary-reared 56 (five field-collected were anesthetized by chloroform...
The Coronavirus pandemic is recording unprecedented deaths worldwide. temporal distribution and burden of the disease varies from setting to based on economic status, demography geographic location. A rapid increase in number COVID-19 cases being reported Africa as June 2020. Ethiopia first case 13 March Limited molecular laboratory capacity resource constrained settings a challenge diagnosis ever-increasing overall management disease. In this article, Ethiopian Public Health Institute...
Abstract Background Encouraged by the previous success in malaria control and prevention strategies, Ethiopian ministry of health launched elimination with a stepwise approach primarily targeting low-transmission Districts their adjacent areas/zones order to shrink country’s map progressively. Hence, this community survey was conducted establish baseline information at preliminary phase targeted settings. Methods A community-based cross-sectional 20 malaria-elimination selected from five...
Abstract Background Malaria rapid diagnostic tests (RDTs) have expanded service to remote endemic communities in Ethiopia, where 70% of malaria services per annum are reliant on them. However, strategies threatened by Plasmodium falciparum parasites with deletions the histidine-rich protein 2 and/or 3 ( pfhrp2/3 ) genes. Studies reported gene deletion prevalence Ethiopia that exceeds WHO recommended threshold switch non-HRP2 targeted RDTs for detection P. . Therefore, target alternative...
Glucose-6-phosphate dehydrogenase (G6PD) is cytosolic enzyme, which has a vital role for the integrity and functioning of red blood cells. Lower activity this enzyme leads to occurrence acute haemolytic anaemia after exposure oxidative stressors like primaquine. Primaquine an important drug radical cure Plasmodium vivax blocking transmission falciparum, thereby enhancing malaria elimination. However, there need identify G6PD deficient individuals administer with caution due its side effects....
Purpose: Following the increased Plasmodium falciparum resistance to chloroquine and sulfadoxine/pyrimethamine, Ethiopia adopted artemether/lumefantrine (AL) as first-line treatment for uncomplicated P. in 2004. According recommendation of World Health Organization, this study was carried out regular monitoring efficacy AL treating malaria Metema district, Gondar Zone, Northwest Ethiopia. Patients methods: This is a one-arm prospective 28-day vivo therapeutic among patients aged 6 months...
Background Blood film microscopy is the gold standard approach for malaria diagnosis, and preferred method routine patient diagnosis in health facilities. However, inability of laboratory professionals to correctly detect identify parasites microscopically leads an inappropriate administration anti-malarial drugs patients incorrect findings research areas. This study was carried out evaluate performance facilities under Defense Health Main Department Addis Ababa its surroundings, Ethiopia....
Background Federal Ministry of Health (FMoH) Ethiopia achieved significant declines in malaria mortality and incidence has recently launched elimination selected low transmission settings. Successful calls for rapid accurate diagnosis cases so that the patients can promptly be treated before occurrence transmission. Therefore, this study assessed competency microscopists using panal slides, laboratory service availability readiness terms supplies equipments targeted districts Ethiopia....
Background: Preeclampsia is a multisystem hypertensive disorder of pregnancy with new onset after 20 weeks gestation which leading cause worldwide maternal and fetal morbidity-mortality. Objective: To assess causes ICU admission outcomes among pre-eclampsia eclampsia mothers admitted to Jimma University Specialized Hospital. Methods: A retrospective cross sectional study was conducted at JUSH from May 3 8, 2015, all preeclampsia mother’s records January 1, 2010 December 31, 2014 were...
Although malaria control efforts have currently reduced much of the morbidity and mortality, yet remains a hard problem in many parts Africa.Together with existing efforts, an effective vaccine is expected to act as important weapon fight against burden.Developing efficacious top priority agenda global health program.However, multi-stage life cycle, antigenic variation, vast genetic diversity parasites made development difficult for years.This study was conducted aim reviewing status through...
Unusual ectopic growth of endometrial tissue in the umbilicus a patient who has not undergone surgery is known as primary umbilical endometriosis. When presents with an nodule, whether or they have symptoms, it critical to high index suspicion.Here, we present rare case endometriosis concurrent hyperplasia 40-year-old para II from Western Ethiopia. A total abdominal hysterectomy and nodule excision were performed under general anesthesia. After two months, she returned for follow-up visit...
Introduction: Highly active antiretroviral therapy (HAART) played a critical role in the medical management of HIV infected individuals by restoring immune function and minimizes related outcomes. But treatment failure minimized these advantages leads to an increment morbidity mortality with poor quality life all patients. The aim at this study was assess prevalence HIV-1 its determinants factors among children on first line HAART Felegehiwot Referral Hospital. Methods: Cross sectional...
Abstract Background: Knowledge of the diversity and occurrence termites is important for environmental management, but this unknown in Bahir Dar Zuria area northwestern Ethiopia, which represents tepid to cool sub-moist mid-highlands or also known as middle montane ecozone. The objective study was identify termite taxa determine distribution different habitats Data were collected eight months starting from December 2016 July 2017. Termites using maize stalks baits. Results: A total over...
Abstract Background In Ethiopia, malaria cases are declining as a result of proven interventions, and in 2017 the country launched elimination strategy targeted settings. Accurate diagnosis prompt treatment key components to prevent morbidity stop continuation transmission. However, quality microscopic general is deteriorating burden declines. This study was carried out evaluate competency microscopists performance health facilities on diagnosis. Methods A cross-sectional conducted from 1...
Background: Early and accurate diagnosis of malaria followed by prompt treatment is crucial to reduce morbidity mortality in endemic regions. Presumptive widely practiced where microscopy or rapid diagnostic tests are not readily available. Introduction (RDTs) for the needs prior evaluation their performance relative reference methods. Hence, this study evaluated capacity GENEDIA® Malaria Pf/pan Ag Rapid Test blood smear P. falciparum vivax Ethiopia. Methods: This was a cross-sectional...
Abstract Background: Encouraged by the success in malaria control and prevention strategies, several endemic countries have adopted elimination strategies worldwide. Accordingly, Ethiopian ministry of health launched with a stepwise approach primarily targeting low-transmission districts their adjacent areas/zones order to shrink country’s map progressively. Hence, this community survey was conducted establish baseline information at preliminary phase for measuring future intervention goal....
Abstract Background: In Ethiopia, malaria case is declining as a result of proven interventions and the country launched elimination strategy in targeted settings since 2017. Accurate diagnosis prompt treatment are key components to prevent morbidity stop continuation transmission. However, quality microscopic general deteriorating burden declines. Therefore, this study was carried out toevaluate competency microscopists performance health facilities on diagnosis.Methods: A cross-sectional...
Abstract Background Glucose-6-phosphate dehydrogenase (G6PD) is cytosolic enzyme which has a vital role for the integrity and functioning of red blood cells. Lower activity this leads to occurrence acute hemolytic anemia after exposure oxidative stressors like primaquine. Primaquine an important drug radical cure plasmodium vivax blocking transmission Plasmodium falciparum thereby enhancing malaria elimination. However, there need distinguish G6PD deficient individuals administer with...
Abstract Background The glucose-6 phosphate dehydrogenase (G6PD) enzyme is a cytoplasmic for all human cells, involves in the pentose pathway of metabolic reaction. It protects red blood cells from cellular oxidative damage by detoxifying free radicals. Primaquine can cause acute hemolytic anemia while administered treatment malaria patients with G6PD deficiency. first-line drug against pre-erythrocyte stage P. vivax and gametocyte falciparum. study aims to determine deficiency among...