Pengfei Yang

ORCID: 0000-0003-3681-763X
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About
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Research Areas
  • Spaceflight effects on biology
  • Bone health and osteoporosis research
  • Aluminum Alloys Composites Properties
  • Bone Tissue Engineering Materials
  • Magnesium Alloys: Properties and Applications
  • Fluid Dynamics Simulations and Interactions
  • Microstructure and mechanical properties
  • Sodium Intake and Health
  • Magnetic and Electromagnetic Effects
  • Bone fractures and treatments
  • Aluminum Alloy Microstructure Properties
  • Eicosanoids and Hypertension Pharmacology
  • Electromagnetic Fields and Biological Effects
  • High Entropy Alloys Studies
  • Prosthetics and Rehabilitation Robotics
  • Advanced Sensor and Energy Harvesting Materials
  • Orthopaedic implants and arthroplasty
  • Lower Extremity Biomechanics and Pathologies
  • Radiation Therapy and Dosimetry
  • Numerical methods in engineering
  • Balance, Gait, and Falls Prevention
  • High-Velocity Impact and Material Behavior
  • Vibration and Dynamic Analysis
  • Advanced Materials and Mechanics
  • Effects of Vibration on Health

Northwestern Polytechnical University
2015-2025

Royal Prince Alfred Hospital
2025

The University of Sydney
2025

Zhejiang Normal University
2024

Tsinghua University
2008-2024

Institute of Modern Physics
2020-2024

Chinese Academy of Sciences
2020-2024

Capital Medical University
2024

The First Affiliated Hospital, Sun Yat-sen University
2024

Fujian Medical University
2024

BackgroundThe effect of embolization the middle meningeal artery in patients with subacute or chronic subdural hematoma is uncertain.MethodsWe performed a multicenter, open-label, randomized trial China, involving symptomatic nonacute mass effect. Patients were assigned to undergo burr-hole drainage receive nonsurgical treatment at surgeon's discretion, and each group then randomly assigned, 1:1 ratio, liquid embolic material usual care. whose condition warranted craniotomy excluded. The...

10.1056/nejmoa2401201 article EN New England Journal of Medicine 2024-11-20

Existing and emerging methods in computational mechanics are rarely validated against problems with an unknown outcome. For this reason, Sandia National Laboratories, partnership US Science Foundation Naval Surface Warfare Center Carderock Division, launched a challenge mid-summer, 2012. Researchers engineers were invited to predict crack initiation propagation simple but novel geometry fabricated from common off-the-shelf commercial engineering alloy. The goal of international Fracture...

10.1007/s10704-013-9904-6 article EN cc-by International Journal of Fracture 2014-01-20

Bending, in addition to compression, is recognized be a common loading pattern long bones animals. However, due the technical difficulty of measuring bone deformation humans, our current understanding patterns humans very limited. In present study, we hypothesized that bending and torsion are important regimes human tibia. vivo tibia segment was assessed during walking running utilizing novel optical approach. Results suggest proximal primarily bends posterior (bending angle: 0.15°-1.30°)...

10.1371/journal.pone.0094525 article EN cc-by PLoS ONE 2014-04-14

Glutamine metabolism provides energy to tumor cells and also produces reactive oxygen species (ROS). Excessive accumulation of ROS can damage mitochondria eventually lead cell death. xCT (SLC7A11) is responsible for the synthesis glutathione in order neutralize ROS. In addition, mitophagy remove damaged keep alive. Ionizing radiation kills by causing ROS, which subsequently induces nuclear DNA damage. With this mind, we explored mechanism intracellular induced ionizing hypothesized new...

10.1155/2021/5826932 article EN cc-by Oxidative Medicine and Cellular Longevity 2021-01-01

Laser cladding provides advanced surface treatment capabilities for enhancing the properties of components. However, its effectiveness is often challenged by formation hot cracks during process. This study focuses on mechanism and inhibition in a novel cobalt-based alloy (K688) coating applied to 304LN stainless steel via laser cladding. The results indicate that crack influenced liquid film stability, stress concentration, precipitation phases. Most were found at 25°–45° high-angle grain...

10.3390/ma17163914 article EN Materials 2024-08-07

A hypomagnetic field is an extremely weak magnetic field—it considerably weaker than the geomagnetic field. In deep-space exploration missions, such as those involving extended stays on moon and interplanetary travel, astronauts will experience abnormal space environments fields microgravity. It known that microgravity in causes bone loss, which results decreased mineral density. However, it unclear whether affect skeletal system. present study, we aimed to investigate complex effects of a...

10.1371/journal.pone.0105604 article EN cc-by PLoS ONE 2014-08-26

Static magnetic field (SMF) modulates bone metabolism, but little research is concerned with the effects of SMF on osteoclast. Our previous studies show that osteogenic differentiation strongly correlated strength from hypo (500 nT), weak (geomagnetic field, GMF), moderate (0.2 T) to high (16 SMFs. We speculated intensity had positive or negative nT and 0.2 osteoblast would inversely influence osteoclast differentiation. To answer this question, we examined profound SMFs pre-osteoclast...

10.3109/15368378.2016.1141362 article EN Electromagnetic Biology and Medicine 2016-06-29

Fracture healing is a complex process during which the bone restores its structural and mechanical integrity. Collagen networks minerals are fundamental components to rebuild matrix in callus. It has been recognized that quality could be impaired aging. However, how recovery of fracture influenced by aging, particularly from perspective organization mineralization collagen network callus, remains unclear. A tibial model was established for both young (5 weeks) aged mice (68 weeks). On 21st...

10.1021/acsbiomaterials.4c01490 article EN ACS Biomaterials Science & Engineering 2025-01-20

Abstract Background The goal of cytoreductive surgery for peritoneal malignancy is to remove all macroscopic disease, which occasionally requires the excision umbilicus. While absence umbilicus can be aesthetically undesirable patients, umbilical reconstruction rarely performed due perceived complexity and increased risk wound infections (Sakata et al. in Colorectal Dis 23:1153–1157, 2021). This study aims evaluate outcomes, cosmetic results patient satisfaction during surgery. Methods...

10.1007/s10151-024-03095-y article EN cc-by Techniques in Coloproctology 2025-01-21

Angiogenesis, the formation of new blood vessels, is critical in many normal and pathological processes such as development, reproduction, tumor growth, metastasis. Recently, exposure to moderate-intensity static magnetic fields (1 mT 1 T) has attracted much attention for its potential therapeutic value a noninvasive intervening method. Nevertheless, effects spatial gradient (GSMF) on angiogenesis have not received enough attention. In this study, GSMF (0.2-0.4 T, 2.09 T/m, 1-11 days) were...

10.1002/bem.20501 article EN Bioelectromagnetics 2009-04-29

The diamagnetic levitation as a novel ground-based model for simulating reduced gravity environment has been widely applied in many fields. In this study, special designed superconducting magnet, which can produce three apparent levels (0, 1, and 2 g), namely high magneto-gravitational (HMGE), was used to simulate space environment. effects of HMGE on osteoblast gene expression profile were investigated by microarray. Genes sensitive (0 changes, magnetic field changes sorted the basis...

10.1093/abbs/gmp041 article EN Acta Biochimica et Biophysica Sinica 2009-06-04
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