A5102126070- Alzheimer's disease research and treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Computational Drug Discovery Methods
- Parkinson's Disease Mechanisms and Treatments
- Nerve injury and regeneration
- Amyotrophic Lateral Sclerosis Research
- Nuclear Receptors and Signaling
- Advancements in Battery Materials
- Stress Responses and Cortisol
- Tryptophan and brain disorders
- Ginkgo biloba and Cashew Applications
- Uterine Myomas and Treatments
- Immune Response and Inflammation
- S100 Proteins and Annexins
- Natural product bioactivities and synthesis
- Chromatin Remodeling and Cancer
- Mechanisms of cancer metastasis
- Inflammatory mediators and NSAID effects
- Advanced Battery Materials and Technologies
- Multiferroics and related materials
- Advanced Condensed Matter Physics
- Magnetic and transport properties of perovskites and related materials
- Electrocatalysts for Energy Conversion
- Minimally Invasive Surgical Techniques
- Ureteral procedures and complications
Ulsan National Institute of Science and Technology
2017-2025
Ewha Womans University
2008-2015
Rockefeller University
2013
Deleted Institution
2012
Baewha Women's University
2011
Ewha Womans University Medical Center
2009
Alzheimer's disease (AD) is a progressive neurodegenerative caused by genetic and non-genetic factors. Most AD cases may be triggered promoted environmental Clinical studies have reported that patients with show enhanced baseline levels of stress hormones in the blood, but their physiological significance respect to pathophysiology not clearly understood. Here we report mouse models exposed restraints for 2 h daily on 16 consecutive days increased beta-amyloid (Abeta) plaque deposition...
The transgenic mouse Tg2576 is widely used as a murine model of Alzheimer's disease (AD) and exhibits plaque pathogenesis in the brain progressive memory impairments. Here we report that mice also have severe spinal cord deficits. At 10 mo
Apart from conventional redox chemistries, exploring high-voltage anionic processes, such as pure oxygen or high-valent transition metal ion redox, poses challenges due to the instability of O nonbonding O-dominant energy states. These states are associated with destructive behaviors in layered oxide cathodes, including local structural distortion, cationic disordering, and gas evolution. In this study, we suppress first-cycle voltage hysteresis irreversible 2 evolution Li-rich cathodes...
The development of sodium‐ion batteries is increasingly critical due to the limited availability and rising cost lithium resources, positioning a promising alternative lithium‐ion batteries. Conventional Mn‐based cathode materials often suffer from strong Jahn–Teller effect Mn III , leading structural instability capacity fading. Herein, it demonstrated that activating charge redistribution between adjacent transition metals in Prussian blue analogues, driven by tuning electronic...
Adequate assessment of plaque deposition levels in the brain mouse models Alzheimer disease (AD) is required many core issues studies on AD, including mechanisms underlying pathogenesis, identification cellular factors modifying pathology, and developments anti-AD drugs. The present study was undertaken to quantitatively evaluate patterns brains two popular AD models, Tg2576 Tg-APPswe/PS1dE9 mice. Coronally-cut sections mice were prepared depositions visualized by staining with anti-amyloid...
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that affects motor neurons in the brain and spinal cord, resulting paralysis of voluntary skeletal muscles eventually death, usually within 2~3 years symptom onset. The pathophysiology mechanism underlying ALS not yet clearly understood. Moreover available medication for treating ALS, riluzole, only modestly improves neurological symptoms increases survival by few months. Therefore, improved therapeutic strategies are...
Abstract The topotactic phase transition in SrCoO x ( = 2.5–3.0) makes it possible to reversibly transit between the two distinct phases, i.e. brownmillerite 2.5 that is a room-temperature antiferromagnetic insulator (AFM-I) and perovskite 3 ferromagnetic metal (FM-M), owing their multiple valence states. For intermediate values, phases are expected strongly compete with each other. With oxidation of , however, has been conjectured magnetic decoupled electronic transition, i.e., AFM-to-FM...
Alzheimer's disease (AD) is a neurodegenerative that proceeds with the age-dependent neuronal loss, an irreversible event which causes severe cognitive and psychiatric devastations. In present study, we investigated whether compound, AAD-2004 [2-hydroxy-5-[2-(4-trifluoromethylphenyl)-ethylaminobenzoic acid] has anti-oxidant anti-inflammatory properties, beneficial for brain of Tg-betaCTF99/B6 mice, murine AD model was recently developed to display loss neuritic atrophy in brain....
ObjectiveTo evaluate the potential effect of uterine weight on short-term outcome and incidence complications after total laparoscopic hysterectomy (TLH) for a benign gynecologic disease. MethodsA retrospective medical record review 771 cases where TLH was performed.Patients included in this study underwent either myoma or adenomyosis at Gil Hospital, Gachon University Medicine Science, from March 2006 through December 2010.Participating patients were stratifi ed into three groups: group 1...