Gall bladder carcinoma is a rare malignancy that carries very poor prognosis. Laparoscopic cholecystectomy (LC) established as the gold-standard treatment for symptomatic gall stones. The aim of study was to assess incidence and possibility reducing routine histological examination specimens.Pathology laboratory data specimens over period 5 years (June 2000 July 2005) were analysed retrospectively. case notes retrieved in all cases malignancies.The total number 1452. Four (0.27%) primary...

Fifty-five Escherichia coli isolates were acquired from chicken and turkey meat obtained two slaughterhouses in Tunis. Eighty-nine percent, 80%, 78%, 67%, 45%, 27%, 7%, 4%, 2% of these showed resistance to tetracycline, trimethoprim/sulfamethoxazole, streptomycin, nalidixic acid, ampicillin, chloramphenicol, ciprofloxacin, colistine, gentamicin, respectively. No was detected cefotaxime, ceftazidime, or amikacin. bla(TEM) gene found 22 25 ampicillin-resistant isolates, 1 isolate harbored...

Abstract Angiotensin-(1-7) [Ang-(1-7)] reportedly potentiates hypotensive responses to bradykinin. We studied whether increases in circulating bradykinin would alter Ang-(1-7). In rats anesthetized with thiobutabarbital, infusion (5 μg/kg per minute IA) resulted a rapid decrease mean arterial pressure (MAP) of about 20 mm Hg ( P <.01, n=9), although MAP slowly increased by 10 after 15 minutes. When Ang-(1-7) (20, 80, and 380 nmol rat was given during infusion, it elicited hypotension at...

Study Design Prospective observational study. Purpose To assess the clinical outcome after early versus late decompression for traumatic cervical cord injury. Overview of Literature Traumatic spinal injury is common globally with most tragic outcomes in spine. Although recent studies have shown that results more favourable outcome, its authority yet to be established. Methods on 98 patients a was conducted over period 5 years. The who were operated within 24 hours onset primary (n=34)...

Traumatic Brain Injury (TBI) is one of the leading causes for morbidity, mortality and economic loss. The impact much worse in developing countries like Pakistan. objective our study was to highlight etiological pattern distribution TBI Pakistan.From July 2009 June 2011, 1378 patients presenting Accident Emergency Department with head injury were included study. Patients underwent detailed clinical radiological evaluation as per trauma protocol.The most commonly affected age group 21 30...

Traumatic intracerebral contusion is a frequent factor culminating in death and disability, its progression relates to unfavorable outcome. We evaluated the radiological factors associated with hemorrhagic of contusions (HPC).Two hundred forty-six patients were enrolled this prospective cohort over period 1 year. Contusion volume was quantified using "ABC/2" technique, whereas considered as >30% increase initial volume. Univariate multivariate statistics used examine correlation between risk...

A prospective study on spinal tuberculosis (TB) at a tertiary care hospital in an endemic region.The aim of the is to reiterate importance conservative management TB.Spinal can present with wide spectrum symptoms, back pain being most common symptom. It leading cause non-traumatic paraplegia developing countries. There emerging trend operate patients early TB.Forty-seven (M=14, F=33) were enrolled during four year period. Initially, all subjected computed tomography guided percutaneous...

Introduction Motorcycles are an inexpensive and popular mode of transportation in Karachi, Pakistan, despite the increasing number motor vehicle injuries. Although motorcycle-related injuries have been studied previously, to our knowledge, there no published reports on orthopedic associated with motorcycles crashes. Methods We conducted a cross-sectional study medical records patients 2015, at Aga Khan University Pakistan. reviewed patient demographic data, helmet use, Glasgow coma score,...

Hydatid cysts commonly affect liver and lung but it can also the brain in rare cases. We report a case of 22 year female with history headache for one half years. Intracranial hydatid cyst was diagnosed on computed tomography scan magnetic resonance imaging. The delivered without rupture using hydrostatic dissection followed by post-operative anthelminthic medication. Surgery remains to be standard management. Amongst surgical techniques described, Dowling's technique is most acceptable....

Diffuse axonal injury (DAI) is a common presentation in neurotrauma. Prognosis variable but can be dependent on the initial of patient. In our study, we evaluated outcome diffuse injury.This study was conducted at tertiary care center from September 2018 to December 2019 and included 133 adult patients with moderate or severe head (GCS ≤ 12) diagnosed have DAI basis MRI. At 3 months, result assessed using Extended Glasgow Outcome Scale (GOS-E).There were total 97 (72.9%) males 36 (27.1%)...

Mini-laparoscopic cholecystectomy (MLC) has widened the horizons of modern laparoscopic surgery. Standard four port (SLC), which long been established as "Gold Standard" for gall bladder diseases, is under reconsideration following advent further minimally-invasive procedures including MLC. Our study aims to provide a comparison between MLC and SLC assesses whether any added benefits.Patients with symptomatic disease undergoing or during 2.5-month period were included in study. Thirty-two...

This study was carried out to evaluate the antimicrobial activity of methanolic extract and different fractions (n-butanol, ethyl acetate, chloroform n-hexane) Glycyrrhiza glabra root. The determined by disc diffusion method minimum inhibitory concentration (MIC) against a panel microorganisms (four bacterial strains, i.e P. multocida, E. coli, B. subtilis S. aureus three fungal i.e. A. flavus, niger R. solani). results indicated that plant mildly potent as agent.

To assess the functional outcome of early surgical management displaced acetabular fractures and complications associated with procedure. This is a case series study data was collected using specialized performance. The included 75 patients sampling technique non-probability purposive type. Patients presenting close more than 2 mm within 10 days injury were included. However, elderly after injury, evidence local infection, severe osteoporotic bone co-morbid such as chronic obstructive...

Introduction: Epidural hematoma (EDH) is a traumatic accumulation of blood between the inner table skull and stripped off dural membrane predominantly consists venous in infants. The study aims to assess outcome pediatric EDH using King's Outcome Scale for Childhood Head Injury (KOSCHI). Materials Methods: A total 72 patients' files were reviewed retrospectively with diagnosis from January 2012 December 2014. Predesigned proforma was filled data patient records. In addition, KOSCHI...

To establish the frequency of evolution in CT appearance from an initial scan to a subsequent within 12 h and prognostic significance such deterioration. All patients who presented Department Neurosurgery, Liaquat National Hospital Medical College with traumatic brain injury received their first 4 were included study. Indications for repeat were: any deterioration neurological status after scan, potentially deteriorating lesion on or without worsening neurology, findings, no improvement...

ABSTRACT Introduction: Adolescent idiopathic scoliosis is the most common type of scoliosis. A Cobb angle 50° will progress beyond age spinal maturity. Surgery over bracing advised at a above or equal to 50°. The aim surgery bring down below prevent reprogression as well improve quality life. objective study analyze efficacy and significance in lifestyle improvement pedicle screw-only fixation system versus more hybrid instrumentation used for surgical treatment adolescent Materials Methods:...

Cranial firearm injuries (CFAIs) are expected to be frequent during warfare; however, it is becoming increasingly common among civilian population in our part of the world. These associated with significant morbidity and mortality addition financial loss. The objective study evaluate pattern gunshot cranium their outcome.The was conducted on 114 patients presenting CFAIs Jinnah Postgraduate Medical Centre, Karachi, Pakistan, between June 2015 January 2019. Patients were evaluated respect...

To understand the differences between operative versus conservative treatment in terms of outcome measured according to American Spinal Injury Association (ASIA) impairment scale (AIS) patients with gunshot acquired spinal cord injuries.A total 168 were included this retrospective study. The AIS score was recorded for all survivors who provided consent after emergence from shock. Demographic information and level injury also recorded. Patients categorized management approach, at 6-month...