A5021412790- Microbial Community Ecology and Physiology
- Algal biology and biofuel production
- Protist diversity and phylogeny
- Polyamine Metabolism and Applications
- Microbial Metabolic Engineering and Bioproduction
- Amino Acid Enzymes and Metabolism
Universität Greifswald
2022-2023
Abstract Formaldehyde is a toxic metabolite that formed in large quantities during bacterial utilization of the methoxy sugar 6‐ O ‐methyl‐ d ‐galactose, an abundant monosaccharide red algal polysaccharide porphyran. Marine bacteria capable metabolizing porphyran must therefore possess suitable detoxification systems for formaldehyde. We demonstrate here formaldehyde marine Flavobacterium Zobellia galactanivorans proceeds via ribulose monophosphate pathway. Simultaneously, we show genes...
Marine algae produce complex polysaccharides, which can be degraded by marine heterotrophic bacteria utilizing carbohydrate-active enzymes. The red algal polysaccharide porphyran contains the methoxy sugar 6-O-methyl-D-galactose (G6Me). In degradation of porphyran, oxidative demethylation this monosaccharide towards D-galactose and formaldehyde occurs, is catalyzed a cytochrome P450 monooxygenase its redox partners. direct proximity to genes encoding for key enzymes demethylation,...