A one-pot procedure for the synthesis of [Cu(X)(NHC)] (X = Cl, Br, I) is reported. The reaction applicable to a wide range saturated and unsaturated NHC ligands, scalable proceeds under mild conditions using technical grade solvents in air.

The N-methylation of amines using CO2 and PhSiH3 as source CH3 was efficiently performed a N-heterocyclic carbene copper(i) complex. methodology found compatible with aromatic aliphatic primary secondary amines. Synthetic computational studies have been carried out to support the proposed reaction mechanism for this transformation.

Carbene transition-metal complexes have become a prevalent family of catalysts enabling numerous organic transformations. Their facile synthetic access is matter great importance. To this end, the Cu(I) -NHC transfer methodology has emerged as powerful alternative presenting attractive advantages over other methods. Herein, we report remarkable ability copper to not only NHCs but also types carbenes such abnormal (aNHCs), cyclic (alkyl)(amino)carbenes (CAACs), and mesoionic (MICs) various...

Titanocalix[4]arenes are shown to be active for the ROP of cyclic esters under N₂ or air with mono-methoxy complex [Ti(NCMe)Cl(<italic>p-tert</italic>-butylcalix[4]arene(O)₃(OMe))] performing best.

In this review, we discuss the use of titanium complexes bearing either bridged diphenolate or calix[n]arene (n = 4, 6, 8) ligation, in formation plastics from α-olefins via ring opening polymerization (ROP) cyclic esters. The syntheses, molecular structures and catalytic behaviour these systems are discussed, as well where possible, properties resultant polymers.

Homo- and heteroleptic bis-NHC copper(I) complexes have been efficiently used as carbene transfer reagents to Au Pd. The simple straightforward procedure allows for the synthesis of well-known gold well novel cationic Pd(II) species.

In this work, two compounds belonging to the BODIPY family, and previously investigated for their photosensitizing properties, have been bound amino-pendant groups of three random copolymers, with different amounts methyl methacrylate (MMA) 2-(dimethylamino)ethyl (DMAEMA) in backbone. The P(MMA-ran-DMAEMA) copolymers inherently bactericidal activity, due amino DMAEMA quaternized nitrogens bounded BODIPY. Systems consisting filter paper discs coated conjugated were tested on model...

Photodynamic therapy (PDT) relies on the combined action of a photosensitizer (PS), light at an appropriate wavelength, and oxygen, to produce reactive oxygen species (ROS) that lead cell death. However, this therapeutic modality presents some limitations, such as poor water solubility PSs their limited selectivity. To overcome these problems, research has exploited nanoparticles (NPs). This project aimed synthesize PS, belonging BODIPY family, covalently link it two NPs differ in lipophilic...

Production of the high industrial value cis,cis-muconic acid (ccMA) from renewable biomasses is main interest especially when biological (green) processes are used. We recently generated a E. coli strain expressing five recombinant enzymes to convert vanillin (VA, lignin) into ccMA. Here, we optimized growing cell approach in bioreactor for ccMA production. The medium composition, fermentation conditions, and VA addition were tuned: pulse-feeding at 1 mmol/h allowed reach 5.2 g/L 48 h (0.86...

A series of organoaluminium imino-amido complexes the type {[ArNC(Me2)C(Me)[double bond, length as m-dash]NAr]AlMe2} (Ar = 2,6-iPr2C6H3 (1), Ar 2,6-Et2C6H3 (2); 2,6-Me2C6H3 (3) have been prepared via reaction AlR3 and respective α-diimine. Similar bis(α-diimine) [ArN[double m-dash]C(Me)C(Me)[double m-dash]N-]2 2,6-iPr2C6H3) with AlMe3 afforded bimetallic complex [ArN-C(Me)2C(Me)[double m-dash]NAlMe2]2 (4), whilst acetyl-imino compound [O[double m-dash]NAr] 2,6-Et2C6H3) {[OCMe2CH(Me)[double...

Interaction of p-tert-butylcalix[6]areneH6, L1H6, with [TiCl4] afforded the complex [Ti2Cl3(MeCN)2(OH2)(L1H)][Ti2Cl3(MeCN)3(L1H)]·4.5MeCN (1·4.5MeCN), in which two pseudo-octahedral titanium centres are bound to one calix[6]arene. A similar reaction but employing THF resulted ring-opened product [Ti4Cl2(μ3-O)2(NCMe)2(L)2(O(CH2)4Cl)2]·4MeCN (2·4MeCN), where LH4 = p-tert-butylcalix[4]areneH4. L1H6 [TiF4] (3 equiv.) led, after work-up, [(TiF)2(μ-F)L1H]2·6.5MeCN (3·6.5MeCN). Treatment...

Synthetic polymers have a key role in modern society as they allowed for great technological advancement since their discovery. However, the use of fossil-fuel-based raw materials and pollution derived from plastics accumulation environment raised enormous concern, driving research efforts toward identification more sustainable alternatives. Bio-based functional molecules susceptible to ring-opening (co)polymerisation [RO(C)OP], such lactones, cyclic carbonates, oxiranes, represent an...

In situ synthesis of topologically modified linear polyethylenes (PE) using single-site polymerization catalysis is a challenging task, but it can enable the production valuable advanced polymer materials with tailored properties. Described herein an investigation aimed at efficient generation long-chain branches (LCB) in PEs Al–alkenyl species, namely, iBuAl(oct-7-en-1-yl)2 (Al-1), combination homogeneous rac-{EBTHI}ZrCl2 (Zr-1)/MAO or heterogeneous MAO on silica-supported-rac-{EBTHI}ZrCl2...

We have structurally characterized a number of lithiated calix[4]arenes, where the bridge in calix[4]arene is thia (-S-, LSH4), sulfinyl (-SO-, LSOH4), sulfonyl (-SO2-, LSO2H4), dimethyleneoxa (-CH2OCH2-, LCOCH4) or methylene (-CH2-, LH4). In case L4SH4, interaction with LiOtBu led to isolation complex [Li8(L4S)2(THF)4]·5THF (1·5THF), whilst similar L4SOH4 [Li6(L4SOH)2(THF)2]·5(THF) (2·5THF). Interestingly, mixed sulfinyl/sulfonyl complexes...

The reactions of the titanium alkoxide [Ti(OR)4] (R = Me, nPr, iPr, tBu) with acids 2,2′-Ph2C(X)(CO2H), where X OH and NH2, i.e., benzilic acid (2,2′-diphenylglycolic acid, L1H2), 2,2′-diphenylglycine (L2H3), have been investigated. variation reaction stoichiometry allows for isolation mono-, bi-, tri or tetra-metallic products, structures which determined by X-ray crystallography. ability resulting complexes to act as catalysts ring opening polymerization (ROP) ε-caprolactone (ε-CL)...

Interaction of [Sc(OR)3] (R = iPr or triflate) with p-tert-butylcalix[n]arenes, where n 4, 6, 8, affords a number intriguing structural motifs, which are relatively non-toxic (cytotoxicity evaluated against cell lines HCT116 and HT-29) were capable the ring opening polymerization (ROP) cyclohexene oxide.