A5031832654- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Hepatitis C virus research
- COVID-19 Clinical Research Studies
- Hepatitis B Virus Studies
- Organ Transplantation Techniques and Outcomes
- SARS-CoV-2 and COVID-19 Research
- Microscopic Colitis
- Helicobacter pylori-related gastroenterology studies
- Diabetes and associated disorders
- Diagnosis and treatment of tuberculosis
- Inflammatory Bowel Disease
- Gastrointestinal disorders and treatments
- Pancreatic and Hepatic Oncology Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Gastric Cancer Management and Outcomes
- Gastrointestinal motility and disorders
- Congenital gastrointestinal and neural anomalies
- Immune Cell Function and Interaction
- Pediatric Hepatobiliary Diseases and Treatments
- Sepsis Diagnosis and Treatment
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Alzheimer's disease research and treatments
- Liver physiology and pathology
- Appendicitis Diagnosis and Management
Kafrelsheikh University
2016-2025
Office of Infectious Diseases
2023
Novem (Netherlands)
2020
Tanta University
2018
Zagazig University
2018
Tanta University Hospital
2016
Background Globally, hepatocellular carcinoma (HCC) is the third most frequent cause of cancer-related mortality. In recent years, transarterial chemoembolization, radiofrequency ablation, and microwave ablation (MWA) have been accepted as treatment modalities for patients with surgically unresectable HCC. Aim this work This study aimed to compare combination or MWA, followed by performed in a single session. Patients methods was carried out on 50 nonresectable single-lesion HCC, who were...
Screening endoscopy is recommended for early detection of esophageal varices (EVs) in cirrhotic patients with portal hypertension. However, this approach limited by its invasiveness and cost. The aim the study was to determine if platelet count can predict presence EVs, especially large (grade III, IV) EVs need prophylactic therapy, a cohort Egyptian liver cirrhosis. In all, 110 cirrhosis were prospectively analyzed. medium or correlated patients’ FIB-4. Esophageal present 87 (79.09%)...
The expression of programmed cell death ligands on tumor cells has a role in the suppression antitumor immunity, resulting immune evasion.In this study, we evaluated prognostic value soluble form death-ligand1 (sPD-L1) Egyptian hepatocellular carcinoma (HCC) patients.This prospective cohort study was performed between November 2016 to 2018 85 individuals (25 HCC patients, 25 with vascular invasion and/or extrahepatic metastasis, patients liver cirrhosis, 10 healthy controls). levels sPD-L1...
It is essential to comprehend the humoral immune response severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and its vaccines maximize effectiveness of anti-SARSCoV-2 community immunization efforts. The aim this cross-sectional study was determine seroprevalence anti-SARS-CoV-2 IgM/IgG among newcomer students at Kafr Elsheikh University in Egypt, whether they had been vaccinated or not. Blood samples from 400 healthy (200 non-vaccinated 200 vaccinated) were evaluated for presence...
Introduction: irritable bowel syndrome is a recurrent chronic gastrointestinal functional disorder. Despite it not dangerous; carries significant feedback on self-confidence and quality of life. Medical students are expected to develop because they subjected stress due over academic pressure. The objectives were investigate prevalence, detect the related risk factors in this specific group Egyptian people.
Identifying coronavirus disease 2019 (COVID-19) vaccine acceptance and associated factors among people living with HIV (PLHIV) in the Middle East North Africa region is important to meet need for broad-scale vaccination against COVID-19.To investigate COVID-19 rate PLHIV region.An online cross-sectional survey was conducted currently Egypt, Tunisia Saudi Arabia between March 2021 August 2021.Of 540 respondents, 19.3% reported already being vaccinated (n = 104), 32.0% responded 'definitely...
Background: Single nucleotide polymorphisms provide information on individuals’ potential reactions to environmental factors, infections, diseases, as well various therapies. A study SNPs that influence SARS-CoV-2 susceptibility and severity may a predictive tool for COVID-19 outcomes improve the customized coronavirus treatment. Aim: To evaluate role of human leukocyte antigens DP/DQ IFNλ4 among Egyptian patients. Participants Methods: The involved 80 patients with severe COVID-19, mild...
To directly visualize Helicobacter pylori (H. pylori) by the highly sensitive and specific technique of immunohistochemical staining in colonic tissue from patients newly diagnosed with ulcerative colitis (UC).Colonoscopic biopsies thirty UC controls were stained Giemsa stain for detection H. tissue. Results confirmed testing Ag stool then infected randomized to receive either anti treatment or placebo.Twelve/30 (40%) positive Giemsa, 17/30 (56.6%) immunohistochemistry stain. Among control...
Background: As hepatocellular carcinoma (HCC) arising from chronic hepatitis C virus (HCV) infection in liver cirrhosis is a major problem public health, early and rapid prediction of HCC urgent. We hypothesized that single nucleotide polymorphism the Apa1 SNP vitamin D receptor may help diagnosis.Methods: recruited 3 groups: 80 patients with HCV cirrhosis, cirrhotic free healthy controls. rs7975232 was detected by PCR- RFLP technique. Routine laboratory markers were determined standard...
Background . Portal hypertensive gastropathy (PHG) is a common anomaly with potential for bleeding found in portal hypertension. Blood ammonia levels correlate well liver disease severity and existence of portosystemic shunts. Increased results vasodilation hepatic stellate cell activation causing exacerbating Objective To assess the relation blood to presence cirrhosis. Methods This cross-sectional study included 381 cirrhotics undergoing screening esophageal varices (EV) divided into group...
Spontaneous bacterial peritonitis is considered a precipitating factor for renal impairment in patients with liver cirrhosis. No specific study addressing this problem has been reported. This aimed to detect the incidence and predictive factors of hepatorenal syndrome these patients.This enrolled 121 hepatic cirrhotic spontaneous peritonitis. History taking, clinical examination, laboratory investigations including ascitic fluid analysis were carried out. Kidney function tests repeated 3...
Background and study aim: Amebiasis is a prevalent infection worldwide associated with colitis that may mimic different types of colitis. The aim this to determine the prevalence amebiasis among patients endoscopically histologically confirmed Egyptian patients. Patients Methods: This was conducted in period from June 2017 March 2018. final analysis were divided into 2 groups according their histopathologic features: Group I: Inflammatory bowel disease (IBD) comprised 60, 49 diagnosed as...
Different genetic and environmental factors are implicated in type I diabetes (T1DM) pathogenesis. About 50% of the susceptibility for T1DM is related to human leukocyte antigen (HLA) genes. Other non-HLA genes have variable roles destruction pancreatic β cells. A highly gene called endoplasmic reticulum associated with processing 1(ERAP1) shares activating autoreactive CD8+ T lymphocytes, peptide trimming, subsequent cells destruction. Local production inflammatory cytokines within islets...
Background Hepatitis C virus (HCV) constitutes a global public health problem in Egypt, as it has the highest worldwide prevalence. This study aimed at determining seroprevalence of HCV among newcomer students Kafrelsheikh University, Egypt. Methods A cross‐sectional serosurvey was conducted including 9049 students. Medical examination, ultrasonography, and laboratory investigations were done. Liver function tests antibody testing carried out for all who gave an informed consent; HCV‐RNA...
Abstract Background and Aim Liver cirrhosis (LC) is commonly associated with portal hypertensive gastropathy (PHG), it causes gastrointestinal (GI) bleeding. Esophagogastroduodenoscopy (EGD) the gold standard in diagnosing PHG. Besides its invasiveness, disadvantages of EGD include psychological financial problems. We aimed to evaluate diagnostic accuracy different noninvasive screening tools predicting Methods This cross‐sectional study was conducted on 100 patients LC who were divided into...
Abstract Background This work aims to develop clinical practice recommendations for the management of systemic sclerosis (SSc). Results Fourteen expert panels had completed two rounds surveys. After end round 2, were released and distributed on 11 domains. The percentage agreement was 92.3% 100%. All key questions answered at second with agreement. Conclusion guideline tried tackle gaps in research that limit treatment options. Stratifying patients according their disease domains has helped...
Background: Single nucleotide polymorphisms (SNPs) of IL-28B and/or ICAM-1 could have a role in expecting response from HCV infected patients to direct antiviral agents (DAAs). Objective: The aim the current study was investigate impact rs12979860 and rs8099917, and, rs281437 SNPs on treatment with sofosbuvir + Daclatsvir ± Ribavirin, among HCV-infected Egyptian patients. Methods: Whole blood genomic DNA extracted 120 participants (80 40 healthy volunteers). were subdivided into responders...
Emara, Mohamed H.; Ahmed, Mohammed Mahros, Aya M.; Amer, Ibrahim F.; Elkerdawy, Mahmoud A. Author Information
Background and study aim: The incremental global spread of the SARS-CoV-2 virus imposes an enormous burden on medical health systems. We focused on determining predictors for COVID-19 patient's course illness what level care will be actually needed at hospital admission. Patients Methods: 170 symptomatic COVID-19 Egyptian patients were gleaned from August 2020 to January 2021, categorized into a group that managed home or ward admitted and necessitated ICU hospitalization Tanta...
The endoscopic retrograde cholangiopancreatography (ERCP) is considered a main therapeutic intervention in the management of biliary and pancreatic disorders.In average risk populations it associated with adverse events.The most common event post-ERCP pancreatitis.Patients liver cirrhosis are increasingly seen ERCP theaters different indications for ERCP.Because cirrhotic patients prone to complications expected that they develop more events when operated ERCP.Bleeding diathesis serious...
Abstract Background Cognitive impairment in patients with hepatitis C virus (HCV) is reported the early onset of HCV infection without hepatic cirrhosis or marked liver impairment. Methods currently available to identify risk for cognitive do not combine enough sensitivity and specificity. The present study aimed evaluate P 300 components event-related potential (ERP) abnormalities as valid biomarkers prediction diagnosis newly diagnosed infection. This a case–control involved fifty age...