- RNA Interference and Gene Delivery
- Virus-based gene therapy research
- Advanced biosensing and bioanalysis techniques
- Effects of Radiation Exposure
- Cancer Cells and Metastasis
- MicroRNA in disease regulation
- Advanced Radiotherapy Techniques
- Fetal and Pediatric Neurological Disorders
- Reproductive Biology and Fertility
- Cancer Genomics and Diagnostics
- Renal Transplantation Outcomes and Treatments
- Folate and B Vitamins Research
- Nitric Oxide and Endothelin Effects
- Single-cell and spatial transcriptomics
- Glutathione Transferases and Polymorphisms
- Bacillus and Francisella bacterial research
- Genomics, phytochemicals, and oxidative stress
- Redox biology and oxidative stress
- Genetic Mapping and Diversity in Plants and Animals
- Organ Transplantation Techniques and Outcomes
- Anesthesia and Neurotoxicity Research
- Platelet Disorders and Treatments
- Mesenchymal stem cell research
- Cancer-related molecular mechanisms research
- Radiation Therapy and Dosimetry
Research Centre for Medical Genetics
2012-2018
Research Institute of Medical Genetics of Russian Academy of Medical Sciences
2012-2014
Russian Academy of Sciences
2011-2013
Academy of Medical Sciences
2012
Introduction: Human blood normally contains circulating cell-free DNA (cirDNA). Cell-free (cfDNA) present in cell culture medium is termed extracellular (ecDNA). Its concentration, GC content and oxidation level depend on physiological state of the organism. cirDNA could probably be one aggressive factors encountered by therapeutic stem cells. The authors hypothesize that oxidized influence their survival rate. They aimed to uncover effects ecDNAs, including ecDNA cultivated primary tumor...