Alexander Tai

ORCID: 0000-0003-3800-6101
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About
Contact & Profiles
Research Areas
  • Meningioma and schwannoma management
  • Spinal Fractures and Fixation Techniques
  • Head and Neck Surgical Oncology
  • Neurofibromatosis and Schwannoma Cases
  • Facial Nerve Paralysis Treatment and Research
  • Vascular Malformations Diagnosis and Treatment
  • Trigeminal Neuralgia and Treatments
  • Spine and Intervertebral Disc Pathology
  • Glioma Diagnosis and Treatment
  • Neuroscience and Neuropharmacology Research
  • Intracranial Aneurysms: Treatment and Complications
  • Spinal Dysraphism and Malformations
  • Axon Guidance and Neuronal Signaling
  • Cervical and Thoracic Myelopathy
  • Cerebral Venous Sinus Thrombosis
  • Peripheral Nerve Disorders
  • Ear Surgery and Otitis Media
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Brain Metastases and Treatment
  • Management of metastatic bone disease
  • Fetal and Pediatric Neurological Disorders
  • Travel-related health issues
  • Vestibular and auditory disorders
  • Sexual function and dysfunction studies
  • Traumatic Ocular and Foreign Body Injuries

Barrow Brain and Spine
2024

University of South Florida
2023-2024

MedStar Georgetown University Hospital
2013-2022

Georgetown University
2013-2022

Monash Health
2016

Georgetown University Medical Center
2013-2014

Zero to Three
2013

OBJECTIVE: To examine tumor control, hearing preservation, and complication rates after frameless fractionated stereotactic radiosurgery (SRS) in patients with vestibular schwannomas (VS). METHODS: Thirty seven treated SRS from 2002 to 2011 were retrospectively analyzed. Ninety five percent 25 Gy 5 fractions, targeting a median volume of 1.03 cc (range 0.14-7.60). RESULTS: With follow-up 4.25 years (range, 15months-9 years), no tumors required an additional treatment resulting 100% control...

10.3389/fonc.2013.00121 article EN cc-by Frontiers in Oncology 2013-01-01

Effective short-term outcomes have been well documented for trigeminal neuralgia (TN) patients treated with Gamma Knife radiosurgery (GKRS) reported success rates of 70-90 % median follow-up intervals 19-75 months. Fewer series, however, described uniform long-term data. In this study, we report our institutional in GKRS after a minimum 36 months.Thirty-six consecutive medically intractable TN received radiation dose 45 Gy applied single 4-mm isocenter to the affected nerve. Follow-up data...

10.1007/s13566-013-0134-3 article EN cc-by Journal of Radiation Oncology 2013-11-19

A handful of studies have reported outcomes with CyberKnife radiosurgery (CKRS) for the treatment trigeminal neuralgia. However, follow-up has been short no minimum required and included patients duration symptoms. Here we report our institutional experience on a 1 year median 28 months (mean 38.84 months). Twenty-five medically surgically intractable TN received CKRS mean marginal radiation dose 64 Gy applied to an average isodose line 86% affected nerve. Follow-up data were obtained by...

10.1186/s13014-014-0257-8 article EN cc-by Radiation Oncology 2014-12-01

Single-position lateral lumbar interbody fusion (SP-LLIF) has recently gained significant popularity due to increased operative efficiency, but it remains technically challenging. Robot-assisted percutaneous pedicle screw (RA-PPS) placement can facilitate in the position. The authors have reported their initial experience with SP-LLIF RA-PPS position, and they compared this accuracy that of prone

10.3171/2021.12.spine211176 article EN Journal of Neurosurgery Spine 2022-02-09

Abstract BACKGROUND Cadaveric studies on surgical anatomy and approaches are hampered by the limited number of specimens. Virtual reality (VR) technology can overcome this limitation, allowing for more in-depth statistical analysis data. OBJECTIVE To determine benefit a supraorbital ridge osteotomy in craniotomy targeting (1) anterior communicating artery complex (ACOM), (2) lesion 25 mm above tuberculum sellae, using large dataset generated VR. METHODS Computed tomography scans 30 subjects...

10.1093/ons/opz201 article EN Operative Neurosurgery 2019-07-23

Prior studies have identified two anatomically and neurochemically distinct cellular compartments within the mammalian striatum, termed striosomes matrix, which express μ-opioid receptors (μOR) EphA4, respectively. Here we identify characterize an additional compartment in rat striatum composed of neurons that EphA7. In situ hybridization immunohistochemical data indicate expressing EphA7 mRNA protein are arranged a banded "matrisome-like" pattern confined to matrix dorsal striatum. Within...

10.1002/cne.23308 article EN The Journal of Comparative Neurology 2013-01-24

OBJECTIVE Despite advancement of surgical techniques, the attachments petroclival meningiomas near central clival depression (CCD) remain difficult to visualize. With existing methods, amount tumor CCD that is inaccessible through various approaches cannot be compared. Tumors distort brainstem, changing size operative corridor for some but not all approaches; therefore, using cadavers with normal posterior fossae makes it impossible compare different tumor. The authors used virtual reality...

10.3171/2021.5.focus201036 article EN Neurosurgical FOCUS 2021-08-01

Background and Purpose: Middle cerebral peduncle (MCP) edema has been described to occur in up 35.7% of vestibular schwannomas (VS). Tumor size associated with the occurrence MCP FLAIR signal seems be long-term thickness MCP. However, no clear data shows any eventual correlation between pre postoperatively postoperative cranial nerve outcomes. The aim this retrospective study is investigate correlations outcomes surgically treated VS patients.

10.1055/s-0044-1780096 article EN Journal of Neurological Surgery Part B Skull Base 2024-02-01

Introduction: Elevated neutrophil to lymphocyte ratios (NLR) has been shown be a predictor of vestibular schwannoma (VS) growth, as well prognostic factor in other cancers. Middle cerebral peduncle (MCP) MRI FLAIR and thickness changes are commonly observed VS. This study investigates the correlations between NLR MCP VS pre- postoperatively.

10.1055/s-0044-1780094 article EN Journal of Neurological Surgery Part B Skull Base 2024-02-01

Background and Purpose: Vestibular Schwannomas (VS) represent 6–8% of all intracranial tumors have recently been implicated to be dependent on inflammatory processes. Atorvastatin is currently one the most frequently prescribed medications in United States. It has shown literature that atorvastatin anti-inflammatory effects. However, there are no studies relating vestibular schwannomas. This study attempts explore relationship between perioperative cranial nerve (CN) outcomes neutrophil...

10.1055/s-0044-1780394 article EN Journal of Neurological Surgery Part B Skull Base 2024-02-01

Background and Purpose: Elevated neutrophil to lymphocyte ratios (NLR) has been shown be predictive of vestibular schwannoma (VS) growth, a prognostic factor in other cancers. This study investigates the correlations between NLR cranial nerves commonly affected by VS, including vestibulocochlear nerve (CNVIII), facial (CNVII), trigeminal (CNV).

10.1055/s-0044-1780089 article EN Journal of Neurological Surgery Part B Skull Base 2024-02-01

We present a case in which retrocondylar far-lateral approach was utilized to resect hemangioblastoma at the craniocervical junction. The patient 33-year-old man presenting with 2 months of symptoms referable compression junction (i.e., dizziness and gait instability). Though neurologically intact on exam, his imaging demonstrated highly vascular cystic lesion dorsolateral medulla left consistent hemangioblastoma. Virtual reality software critical visualize patient's relationship vertebral...

10.1055/s-0039-1698821 article EN cc-by-nc-nd Journal of Neurological Surgery Part B Skull Base 2019-10-22

Background: The portion of the occipital condyle that is "safe" to remove remains controversial in transcondylar approach. We aimed correlate gain exposure with incremental removal determine if there a point where further drilling yields diminishing gains.

10.1055/s-0040-1702445 article EN Journal of Neurological Surgery Part B Skull Base 2020-02-01

Tai, Alexander MD; Felbaum, Daniel Liu, Ai-Hsi; Mason, Robert Bryan MD, FACS; Armonda, Rocco Sava, Jack Aulisi, Edward F

10.1093/neuros/nyx417.336 article EN Neurosurgery 2017-09-01
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