A5036003701- Circular RNAs in diseases
- Neural dynamics and brain function
- Advanced Measurement and Detection Methods
- Cancer-related molecular mechanisms research
- Neuroscience and Neuropharmacology Research
- Maritime Ports and Logistics
- Maritime Navigation and Safety
- Neuroscience and Neural Engineering
- Advanced Nanomaterials in Catalysis
- Optical Systems and Laser Technology
- Remote Sensing and Land Use
- Educational Reforms and Innovations
- CRISPR and Genetic Engineering
- Vehicle License Plate Recognition
- Neurogenesis and neuroplasticity mechanisms
- Quantum Dots Synthesis And Properties
- China's Ethnic Minorities and Relations
- Cerebrovascular and genetic disorders
- Developmental Biology and Gene Regulation
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Inflammatory Biomarkers in Disease Prognosis
- Chemokine receptors and signaling
- Extracellular vesicles in disease
- Regional Economic and Spatial Analysis
- T-cell and B-cell Immunology
Ningbo University
2023-2024
State Key Laboratory of Medical Neurobiology
2020-2024
Fudan University
2020-2024
Zhongshan Hospital
2020-2024
Ningbo First Hospital
2020-2022
Southeast University
2020
Xinjiang University
2016-2017
Zhejiang Ocean University
2013-2014
As an important complication of diabetes mellitus, diabetic cardiomyopathy (DCM) is characterized by a silent development in its earlier stage and deficient cardiomyocyte contractility late stage. So far, little advance has been achieved to reverse this pathological change. LncRNAs are defined as large cluster RNAs without the function encoding proteins, but have capacity controlling gene expression. Interleukin-17 (IL-17), proinflammatory cytokine, key regulator host inflammation....
Long noncoding RNA HOX transcript antisense (HOTAIR) has been studied in multiple diseases, but the role of HOTAIR on chronic heart failure (CHF) through regulation microRNA (miR)-30a-5p and lysine-specific demethylase 3A (KDM3A) remains unexplored. This research aims to probe effects CHF progression via modulating miR-30a-5p target KDM3A. mouse model was established by intraperitoneal injection doxorubicin. The mice were then injected with high-expressed HOTAIR, or KDM3A adenovirus vectors...
Abstract: Stanford type A aortic dissection (TAAD) is one of the most lethal cardiovascular diseases with an extremely high morbidity and mortality rate. LncRNA X-inactive specific transcript (XIST) abundantly expressed in human thoracic dissection, indicating it may play important roles TAAD progression. However, molecular mechanism lncRNA XIST still its infancy. Quantitative real-time PCR (qRT-PCR) was performed to detect expression miR-17 wall tissues patients age-matched healthy...
Homeostatic plasticity maintains the stability of functional brain networks. The axon initial segment (AIS), where action potentials start, undergoes dynamic adjustment to exert powerful control over neuronal firing properties in response network activity changes. However, it is poorly understood whether this involves direct synaptic input AIS. Here, we show that changes GABAergic from chandelier cells (ChCs) drive homeostatic tuning AIS principal neurons (PNs) prelimbic (PL) region, while...
The stability of functional brain network is maintained by homeostatic plasticity, which restores equilibrium following perturbation. As the initiation site action potentials, axon initial segment (AIS) glutamatergic projection neurons (PyNs) undergoes dynamic adjustment that exerts powerful control over neuronal firing properties in response to changes states. Although AIS plasticity has been reported be coupled with activity, it poorly understood whether involves direct synaptic input AIS....
High crystallinity triangle hexagonal Mn<sub>0.45</sub>Cu<sub>0.05</sub>Cd<sub>0.5</sub>S nanocrystals were obtained by partial Cu ion exchange treatment on colloidal pristine Mn<sub>0.5</sub>Cd<sub>0.5</sub>S nanorods for enhanced photocatalytic hydrogen evolution.
The mammillary body is a hypothalamic nucleus that has important functions in memory and spatial navigation, but its developmental principles remain not well understood. Here, we identify progenitor-specific Fezf2 expression the developing develop an intersectional fate-mapping approach to demonstrate Fezf2+ progenitors generate neurons rostral-dorsal-lateral caudal-ventral-medial fashion. Axonal tracing from different temporal cohorts of labeled reveal their topographical organization....
Abstract Ischemia/reperfusion (I/R) of skeletal muscle in the lower limbs is an important factor affecting outcome ischemia patients, with no effective preventive or therapeutic approaches available. The study was to investigate effect syringic acid (SA) on I/R injury. Mice femoral artery models and C2C12 cell hypoxia/reoxygenation (H/R) establish, tissue damage, inflammatory status, high mobility group box 1 (HMGB1) pathway were evaluated using histological analysis, enzyme‐linked...
An assessment framework is made to evaluate the performance factors of marine industries from perspective eco-economics by means AHP and Delphi methods. Results are as follows: Performance index decided ecological performance, economic social with taking priority over index; efficiency economy output value-creating preferred in pursuit low energy-consuming less polluting industries; near future, will make greatest contribution employment.
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Welcome to the WIT Press eLibrary - home of Transactions Wessex Institute collection, providing on-line access papers presented at Institute's prestigious international conferences and from its State-of-the-Art in Science & Engineering publications.
ABSTRACT In recent years, the pulse coupled neural network (PCNN) is widely used in image segmentation, but existing algorithm has an unsatisfactory performance with definition of single threshold, especially uneven illumination or low contrast image. In this paper, order to eliminate impact and improve adaptability, deblocking PCNN utilized. It segments into several rectangles same size. Then applied segment each block stopped by improved OSTU. The emulation experiment shows that method...