A5090025679- Shoulder and Clavicle Injuries
- 3D Printing in Biomedical Research
- Shoulder Injury and Treatment
- Pluripotent Stem Cells Research
- Acute Ischemic Stroke Management
- Systemic Lupus Erythematosus Research
- Hip disorders and treatments
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Health and Disease Prevention
- Obesity, Physical Activity, Diet
- Fibroblast Growth Factor Research
- Kruppel-like factors research
- Mangiferin and Mango Extracts
- Gene expression and cancer classification
- Nanoparticles: synthesis and applications
- Genomics, phytochemicals, and oxidative stress
- Tissue Engineering and Regenerative Medicine
- Adipokines, Inflammation, and Metabolic Diseases
- Renal and related cancers
- Birth, Development, and Health
- Head and Neck Cancer Studies
- Hepatitis C virus research
- Evolutionary Algorithms and Applications
- Alcohol Consumption and Health Effects
- DNA and Biological Computing
Catholic University of Korea
2020-2022
Seoul St. Mary's Hospital
2022
University of Southern California
2022
Konkuk University
2014-2020
Seoul National University Bundang Hospital
2013-2019
Hallym University
2018
Seoul National University
2013
Yonsei University
2009-2010
Adipose tissue is increasingly recognized as an endocrine organ playing important pathophysiological roles in metabolic abnormalities, such obesity, cardiovascular disease, and type 2 diabetes mellitus (T2DM). In particular, visceral adipose (VAT), opposed to subcutaneous tissue, closely linked the pathogenesis of insulin resistance T2DM. Despite importance VAT, its molecular signatures related T2DM have not been systematically explored. Here, we present comprehensive proteomic analysis VATs...
Cytokeratin 19 (KRT19) is a cytoplasmic intermediate filament protein, which responsible for structural rigidity and multipurpose scaffolds. In several cancers, KRT19 overexpressed may play crucial role in tumorigenic transformation. our previous study, we revealed the of as signaling component mediated Wnt/NOTCH crosstalk through NUMB transcription breast cancer. Here, investigated function cancer reprogramming drug resistance cells. We found that expression was attenuated patients-derived...
Purpose: Koreans have been undergoing rapid lifestyle changes that may an effect on patterns of cerebral artery atherosclerosis.This study was aimed at determining the frequency and distribution atherosclerosis in arteries associated temporal over past eight-year period among Korean stroke patients.Materials Methods: By using registry data registered between April 1999 March 2007, we investigated presence, severity, location as determined by angiographic findings.Their annual association...
Fibroblast growth factor 21 (FGF21) is a novel metabolic regulator that has beneficial effects on glucose and lipid metabolism. However, plasma FGF21 levels are paradoxically increased in type 2 diabetes mellitus (T2DM) obesity, suggesting resistance to this ligand. acts mainly adipose tissue ectopic fat accumulation typical feature deterioration such as diabetes, syndrome, cardiovascular disease.To investigate the relationship between accumulation.Subjects who underwent 64-slice...
The prevalence of extracranial (EC) and intracranial (IC) atherosclerosis varies among races. Although several studies have sought to identify specific vascular risk factors that are associated with EC or IC atherosclerosis, the exact relationships uncertain. This study aimed determine if there any for atherosclerosis.For this study, we considered 3,349 consecutive patients who had been entered into a stroke registry between January 1999 June 2007. After exclusion not undergone angiography,...
Abstract Nano‐scale materials are noted for unique properties, distinct from those of their bulk material equivalents. In this study, we prepared spherical silver nanoparticles (AgNPs) with an average size about 30 nm and tested potency to induce neuronal differentiation SH‐SY5Y cells. Human neuroblastoma cells considered ideal in vitro model studying neurogenesis, as they can be maintained undifferentiated state or induced differentiate into neuron‐like phenotypes by several...
Pluripotent stem cells (PSCs) offer a promising tool for regenerative medicine. The clinical application of PSCs inevitably requires large-scale culture in highly defined environment. present study aimed to devise coating materials the efficient adhesion and proliferation human (hPSCs). We tested activity seven fibronectin-derived peptides three laminin-derived attachment hPSCs through their immobilization on bottom dishes by creating fusion protein with mussel protein. Among extracellular...
Preoperative radiological evaluation of the cranial or intracranial extension malignant head and neck tumors is critical in planning curative surgery.To assess diagnostic accuracy computed tomography (CT) combined with magnetic resonance imaging (MRI), compared to CT MRI alone diagnosing direct tumors, using histopathologic results as reference standard.CT images 41 patients abutting skull were retrospectively reviewed. The evaluated for presence absence invasion (erosion/destruction skull),...
Abstract Background In women with autoimmune rheumatic disorders (ARD), pregnancy complications or postpartum events are more frequent compared to the general population. Transplacental autoantibodies cytokines influence various fetal and neonatal outcomes. We growth patterns of babies born mothers ARD versus healthy assess long-term outcomes children ARD. Methods This was a retrospective age-matched cohort analyses from hospitals belonging Catholic University Korea between 2010 2017....
Being born small for gestational age (SGA) has been strongly associated with mortality during the perinatal period and long-term risk of metabolic syndrome, including type 2 diabetes mellitus, hypertension, hyperlipidemia, coronary heart disease. Insulin resistance is an important factor in development syndrome SGA, several proposed hypotheses. Here, we report two cases non-obese adolescent patients early onset who were SGA. Of these, one experienced catch-up growth, while other did not....
Ischemic vaso-occlusive retinopathy as an initial manifestation is rare in pediatric systemic lupus erythematosus (pSLE). A 13-year-old girl presented with two months' history of papules and crusts fatigue, weight loss, abrupt hair loss. Pancytopenia findings compatible SLE, including positive direct Coombs' test, antinuclear antibody (Ab), anti-double stranded DNA Ab, anti-Smith anti-ribonucleoprotein anticoagulant, anti-β2 glycoprotein Immunoglobulin G, anti-cardiolipin were detected....
Background: The study aimed to determine the type of capsular insertion and extent elongation in anterior shoulder instability by quantitatively evaluating their computed tomography arthrographic (CTA) findings, investigate correlation these parameters with surgical outcomes.Methods: We retrospectively reviewed 71 patients who underwent CTA arthroscopic capsulolabral reconstruction for between April 2004 August 2008.The control group comprised 72 diagnosed as isolated II superior labrum...
X-linked inhibitor of apoptosis protein (XIAP) deficiency is a rare immunodeficiency disorder.A 13-month-old boy was diagnosed with pure red cell aplasia (PRCA) and treated steroid cyclosporine.Bone marrow showed diminished erythroid precursors, positive results for Parvovirus B19 Cytomegalovirus (CMV) infection.A genetic study Diamond-Blackfan anemia negative.Five months later, he admitted due to fever lymphadenopathy.PCR still the Parvovirus, CMV, Epstein-Barr virus (EBV).He diffuse large...