A5005565672- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Hepatocellular Carcinoma Treatment and Prognosis
- Renal Transplantation Outcomes and Treatments
- Liver Disease Diagnosis and Treatment
- Organ Donation and Transplantation
- Drug-Induced Hepatotoxicity and Protection
- Systemic Lupus Erythematosus Research
- Clinical Nutrition and Gastroenterology
- Transplantation: Methods and Outcomes
- Genetic and Kidney Cyst Diseases
- Lung Cancer Research Studies
- Electrolyte and hormonal disorders
- Congenital Heart Disease Studies
- Neuroblastoma Research and Treatments
- Sarcoma Diagnosis and Treatment
- Gastrointestinal Tumor Research and Treatment
- Gastrointestinal Bleeding Diagnosis and Treatment
- Gut microbiota and health
- Cytomegalovirus and herpesvirus research
- Pediatric Hepatobiliary Diseases and Treatments
- Immune Response and Inflammation
- Blood disorders and treatments
- Diet and metabolism studies
- Salivary Gland Tumors Diagnosis and Treatment
Amrita Institute of Medical Sciences and Research Centre
2013-2025
Amrita Vishwa Vidyapeetham
2019-2025
Istanbul 29 Mayis University
2025
Nizam's Institute of Medical Sciences
2025
Alaska Heart and Vascular Institute
2021
Indiana University – Purdue University Indianapolis
2021
<ns3:p>Liver diseases cause nearly 2 million deaths worldwide each year, with approximately 1 from cirrhosis complications and another viral hepatitis liver cancer, according to WHO estimates. Liver transplantation (LT) remains the primary curative option, boasting success rates of 85% in first year 75% at five years post-transplant. Despite high costs, LT is considered cost-effective, especially for younger patients active work remaining. However, post-transplant complications, particularly...
Robotic donor hepatectomy (RDH) has been reported with lower morbidity than its open counterpart. Donor safety remains the primary concern precluding wide adaption. We aimed to evaluate complications following RDH and identify their predictive factors. Out of 348 live liver transplants performed between 2018-2021, prospective data 202 were analyzed for by modified Clavien-Dindo grading system. Multivariate analysis operative parameters was done factors predicting CUSUM effect learning curve....
Introduction Acute-on-chronic liver failure (ACLF) patients have the highest propensity for post-liver transplantation (LT) infections and mortality. Liver-associated diseases been one of primary targets synbiotic therapy to augment immunity mitigate infections. However, despite multiple studies showing benefits synbiotics in diseases, data on their use following LT are sparse. Methods analysis This randomised placebo-controlled study aims assess impact ACLF undergoing living donor (LDLT)....
Objective: To assess the safety and efficacy of intermittent inflow occlusion (IIO) during robotic right donor hepatectomy (RDH) for adult living liver transplantation. Summary Background Data: Although evidence supports minimally invasive hepatectomy, its adoption by surgeons remains limited. Key challenges include bleeding parenchymal transection prolonged warm ischemia graft extraction, resulting in morbidity both recipient. Methods: Between April 2022 June 2023, out 123 donors suitable...
Hepatocellular carcinoma (HCC) is still a severe worldwide health issue, and liver transplantation frequently the primary curative option for people who meet criteria it. It challenging to predict long-term graft survival of HCC patients after transplantation. However, it an essential clinical decision-making task. The DeepHit algorithm used in this study grafts using deep learning-based approach. In study, we dataset collected from Amrita Institute Medical Science & Research Centre, Kochi,...
Following liver transplantation (LT), bacterial infections occur in over 70% of recipients leading to significant morbidity and mortality. While synbiotics have been reported decrease infectious complications various surgical procedures, the evidence their benefits following LT remains limited.In this 18-month double-blinded, investigator-initiated, placebo-controlled trial, 100 live donor transplant (LDLT) were randomized receive either synbiotic drug Prowel® (Prepro arm) or a placebo,...
Somatic B-type Raf kinase (BRAF) V600E mutation in exon 15 was frequently found high frequencies associated with papillary thyroid cancer (PTC). The phenotype of these cancers expressed aggressive clinical and pathological features. present study aimed to assess the prevalence BRAF among conventional follicular variants PTC its association tumor factors outcome.Patients who were operated received further treatment for during 2012 included study. analysis done by extracting genomic DNA from...
Robotic right donor hepatectomy (RDH) has been reported from experienced centers with reduced morbidity when compared to open RDH. However, outcomes in donors large grafts/complex biliovascular anatomy are unknown.Out of 170 robotic RDH, 100 had one or more the following: graft weight ≥800 g, type 2/3 portal vein, >1 bile duct hepatic artery and inferior veins >5 mm requiring reconstruction (extended criteria [ExRDH]), while remaining 70 standard (SRDH). After propensity score matching, 66...
In adult right lobe living donor liver transplantation (LDLT), venous drainage of the anterior sector is usually reconstructed on bench to form a neo-middle hepatic vein (MHV). Reconstruction MHV for crucial optimal graft function. The conduits used reconstruction include cryopreserved allografts, synthetic grafts, or recipient portal vein. However, ideal choice remains matter debate. This study compares efficacy native (RPV) with PTFE grafts neo-MHV.Patients in this equivalence-controlled,...
Robotic right live donor hepatectomy (r-LDRH) has been reported with reduced morbidity compared to open (o-LDRH) in few recent series. Nevertheless, its routine use is debated. We present a large series comparing pure r-LDRH o-LDRH. Consecutive performed from June 2018 2020 (n = 102) were consecutive donors undergoing o-LDRH 152) February 2016 2018, period when was not available at this center. Propensity score matched (PSM) analysis of 89 case-control pairs additionally performed. Primary...
Traditionally, deceased donor liver grafts receive dual perfusion (DP) through the portal vein and hepatic artery (HA) either in situ or on back table. HA is avoided living for fear of damage to intima consequent risk thrombosis (HAT). However, biliary vasculature predominantly derived from HA. We hypothesized that antegrade addition table could reduce incidence postoperative complications. Consecutive adult patients undergoing transplantations were randomized after hepatectomy graft...
Although minimally invasive right donor hepatectomy (RDH) has been reported, this innovation is yet to be widely accepted by transplant community. Bleeding during transection, division of hepatic duct (RHD), suturing as well retrieval with minimal warm ischemia are the primary concerns most surgeons. We describe our simplified technique robotic RDH evolved over 144 cases.Right lobe mobilization performed in a clockwise manner from triangular ligament inferior vena cavae up hepatocaval...