Sapir Dahan
A5077609731- Advanced Radiotherapy Techniques
- Sarcoma Diagnosis and Treatment
- Cancer, Hypoxia, and Metabolism
- Cancer Cells and Metastasis
- Immunotherapy and Immune Responses
- RNA Interference and Gene Delivery
- Radiomics and Machine Learning in Medical Imaging
- Diet and metabolism studies
- Cancer Diagnosis and Treatment
- Cancer Research and Treatments
- Advanced biosensing and bioanalysis techniques
Tel Aviv University
2022
Exercise prevents cancer incidence and recurrence, yet the underlying mechanism behind this relationship remains mostly unknown. Here we report that exercise induces metabolic reprogramming of internal organs increases nutrient demand protects against metastatic colonization by limiting availability to tumor, generating an exercise-induced shield. Proteomic ex vivo capacity analyses murine revealed catabolic processes, glucose uptake, mitochondrial activity, GLUT expression. analysis...
<h3>Background</h3> Despite clinical activity of immunotherapy agents in a broad range cancer indications, there is still substantial percentage patients who fail to respond those therapies, and hence, an unmet need address mechanisms tumor immune resistance. One the most promising approaches turn "cold" into "hot" tumor. CpG motif DNA sequence rich unmethylated Cytosine- phosphate Guanine (CpG) nucleotides, prevalent bacterial DNA, eliciting host reaction. AM003 Bispecific Personalized...
<div>Abstract<p>Exercise prevents cancer incidence and recurrence, yet the underlying mechanism behind this relationship remains mostly unknown. Here we report that exercise induces metabolic reprogramming of internal organs increases nutrient demand protects against metastatic colonization by limiting availability to tumor, generating an exercise-induced shield. Proteomic <i>ex vivo</i> capacity analyses murine revealed catabolic processes, glucose uptake,...
Supplementary Data from An Exercise-Induced Metabolic Shield in Distant Organs Blocks Cancer Progression and Metastatic Dissemination
Supplementary Data from An Exercise-Induced Metabolic Shield in Distant Organs Blocks Cancer Progression and Metastatic Dissemination
Supplementary Data from An Exercise-Induced Metabolic Shield in Distant Organs Blocks Cancer Progression and Metastatic Dissemination
Supplementary Data from An Exercise-Induced Metabolic Shield in Distant Organs Blocks Cancer Progression and Metastatic Dissemination
<div>Abstract<p>Exercise prevents cancer incidence and recurrence, yet the underlying mechanism behind this relationship remains mostly unknown. Here we report that exercise induces metabolic reprogramming of internal organs increases nutrient demand protects against metastatic colonization by limiting availability to tumor, generating an exercise-induced shield. Proteomic <i>ex vivo</i> capacity analyses murine revealed catabolic processes, glucose uptake,...