A5023956138- Polymer Surface Interaction Studies
- Luminescence and Fluorescent Materials
- Conducting polymers and applications
- Advanced Polymer Synthesis and Characterization
- Synthesis and properties of polymers
- Dendrimers and Hyperbranched Polymers
- Protease and Inhibitor Mechanisms
- Cell Adhesion Molecules Research
- Electrospun Nanofibers in Biomedical Applications
- Microfluidic and Capillary Electrophoresis Applications
- Polymer composites and self-healing
- Proteoglycans and glycosaminoglycans research
- Nanoparticle-Based Drug Delivery
- Hydrogels: synthesis, properties, applications
- Silk-based biomaterials and applications
- Marine Biology and Environmental Chemistry
- Polyoxometalates: Synthesis and Applications
- Organic Electronics and Photovoltaics
- Antimicrobial agents and applications
- Molecular Sensors and Ion Detection
- Porphyrin and Phthalocyanine Chemistry
Czech Academy of Sciences, Institute of Macromolecular Chemistry
2021-2023
Charles University
2016-2018
Česká Zbrojovka (Czechia)
2017
Layer-by-layer (LbL) polyelectrolyte coatings are intensively studied as reservoirs of bioactive proteins for modulating interactions between biomaterial surfaces and cells. Mild conditions the incorporation growth factors into delivery systems required to maintain protein bioactivity. Here, we present LbL films composed water-soluble N-[(2-hydroxy-3-trimethylammonium)propyl] chitosan chloride (HTCC), heparin (Hep), tannic acid (TA) fabricated under physiological with ability release...
Abstract Zwitterionic polymers are promising non‐fouling materials widely used for surface modification. Here, we report the synthesis of zwitterionic polyaspartamides bearing carboxybetaine and sulfobetaine prepared via combining ring‐opening reaction polysuccinimide with 3‐(dimethylamino)‐1‐propylamine formed tertiary amine side groups 1,3‐propanesultone 4‐bromobutyric acid, respectively. Both have cationic anionic charged on same repeat unit, but they differ in negatively groups. The...
Abstract A novel polythiophene‐based conjugated polymer bearing 1,8‐naphthalimide‐based pendants is prepared by a two‐step modification of regioregular poly[3‐(6‐bromohexyl)thiophene] involving nucleophilic substitution reaction the bromide end‐groups with sodium azide followed robust, copper‐catalyzed Huisgen click 1,8‐naphthalinmide derivative containing an active, N ‐substituted propyne group. Both and highly luminescent‐active synthesized dye are extensively studied in solution UV–vis...
A series of novel metallo-supramolecular polymers was prepared, based on 2,6-bis(2-oxazolinyl)pyridine chelating groups bridged with thiophene, bithiophene and thienothiophene as a linker, beginning from commercially available (chelidamic) acid.
A new type of hydrophilic, biocompatible, and biodegradable polypeptide nanogel depots loaded with the natural serine protease inhibitor α1-antitrypsin (AAT) was applied for inhibition inflammatory mediator trypsin. Two types nanogels were prepared from linear synthetic polypeptides based on biocompatible poly[ N 5 -(2-hydroxyethyl)-ʟ-glutamine- ran - -propargyl-ʟ-glutamine- -(6-aminohexyl)-ʟ-glutamine]- -[2-(4-hydroxyphenyl)ethyl)-ʟ-glutamine] (PHEG-Tyr) or α -ʟ-lysine-grafted...
A new type of hydrophilic, biocompatible, and biodegradable polypeptide nanogel depots loaded with natural serine protease inhibitor α1-antitrypsin (AAT) was applied for inhibition inflammatory mediator trypsin. Further, poly[ N 5 -(2-hydroxyethyl)-L-glutamine- ran - -propargyl-L-glutamine- -(6-aminohexyl)-L-glutamine]- -[2-(4-hydroxyphenyl)ethyl)-L-glutamine] (PHEG-Tyr) α-L-Lysine-grafted α,β-poly[(2-propyne)-D,L-aspartamide- -(2-hydroxyethyl)-DL-aspartamide-...