Emine Merve DEMİRBAŞ BÜYÜKTÜT

ORCID: 0000-0003-3911-7663
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About
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Research Areas
  • Bioactive Compounds and Antitumor Agents
  • Coenzyme Q10 studies and effects
  • PI3K/AKT/mTOR signaling in cancer

Selçuk University
2023

Background/Aims: Juglone, as a naphthoquinone, has been shown to have cytotoxic and apoptotic effects in various cancer cells besides this it was reported anti-invasive anti-metastatic PANC-1 BxPC-3 our previous studies. In study, we investigated the of juglone on GRP75, TFAM mTOR genes encoding key proteins associated with mitochondrial biogenesis activation pancreatic since mitochondria central roles cell survival, metastasis therapeutic resistance. Methods: study; 5, 10, 15 20 μM doses...

10.54005/geneltip.1294642 article EN cc-by-nc Genel Tıp Dergisi 2023-07-04
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