A5015927873- Health Systems, Economic Evaluations, Quality of Life
- Career Development and Diversity
- Higher Education and Employability
- Attention Deficit Hyperactivity Disorder
- Smoking Behavior and Cessation
- Counseling Practices and Supervision
- Sepsis Diagnosis and Treatment
- Dementia and Cognitive Impairment Research
- Respiratory and Cough-Related Research
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Nicotinic Acetylcholine Receptors Study
- Statistical Methods in Clinical Trials
- Treatment of Major Depression
- Child and Adolescent Health
- Asthma and respiratory diseases
- Advanced Causal Inference Techniques
- Child and Adolescent Psychosocial and Emotional Development
- Pharmaceutical Practices and Patient Outcomes
- Cerebrovascular and Carotid Artery Diseases
- Schizophrenia research and treatment
- Neural and Behavioral Psychology Studies
- Reflective Practices in Education
- Pharmaceutical Economics and Policy
- Electroconvulsive Therapy Studies
- Functional Brain Connectivity Studies
Eli Lilly (United States)
2014-2024
The Medical Center of Aurora
2018
York Hospital
2017
Harvard University
1927-2016
Diagnostics for the Real World (United Kingdom)
2016
Brigham and Women's Hospital
2015-2016
Massachusetts General Hospital
2001-2015
Trinity Health Ann Arbor Hospital
2015
Mayo Clinic in Florida
2015
Denver VA Medical Center
2015
Use of nicotine-replacement therapies and the antidepressant bupropion helps people stop smoking. We conducted a double-blind, placebo-controlled comparison sustained-release (244 subjects), nicotine patch (245 placebo (160 subjects) for smoking cessation. Smokers with clinical depression were excluded. Treatment consisted nine weeks (150 mg day first three days, then 150 twice daily) or placebo, as well eight nicotine-patch therapy (21 per during 2 through 7, 14 week 8, 7 9) placebo. The...
Trials of antidepressant medications for smoking cessation have had mixed results. We conducted a double-blind, placebo-controlled trial sustained-release form bupropion cessation. excluded smokers with current depression, but not those history major depression. The 615 subjects were randomly assigned to receive placebo or at dose 100, 150, 300 mg per day seven weeks. target quitting date (or "target quit date") was one week after the beginning treatment. Brief counseling provided base line,...
Loss of muscle mass and strength are natural consequences the aging process, accompanied by an increased prevalence chronic health conditions. Research suggests that in elderly, presence comorbidities may impact mass/strength relationship. The objectives this study were to characterize relationship older adults USA examine a variety on Data obtained from National Health Nutrition Examination Survey 1999–2002 databases. Subjects aged 50 years included present study. Muscle was assessed...
Background: Smoking relapse is common after successful pharmacologic treatment for smoking cessation. No previous studies have examined long-term drug therapy used expressly prevention of relapse. Objective: To evaluate the efficacy bupropion to prevent Design: Randomized, placebo-controlled trial. Participants: 784 healthy community volunteers who were motivated quit and smoked at least 15 cigarettes per day. Intervention: The participants received open-label, sustained-release bupropion,...
Infection is an important complication in cancer patients, which frequently leads to or prolongs hospitalization, and can also lead acute organ dysfunction (severe sepsis) eventually death. While patients are known be at higher risk for infection subsequent complications, there no national estimate of the magnitude this problem. Our objective was identify with severe sepsis project these numbers levels.Data all 1999 hospitalizations from six states (Florida, Massachusetts, New Jersey, York,...
Objective: The prevalence and workplace consequences of adult attention deficit/hyperactivity disorder (ADHD) are unknown. Methods: An ADHD screen was included in a national household survey (n = 3198, ages 18–44). Clinical reinterviews calibrated the to diagnoses Diagnostic Statistical Manual Mental Disorders, 4th edition ADHD. Diagnoses among workers were compared with responses WHO Health Work Performance Questionnaire (HPQ). Results: A total 4.2% had associated 35.0 days annual lost work...
Bupropion has been available in the United States since 1989. Initially a thrice-daily immediate-release formulation, twice-daily sustained-release formulation followed 1996, and, August 2003, once-daily extended-release was introduced. On 15th anniversary of its introduction, we undertook review background/history, mechanism action, formulations, and clinical profile bupropion.Major efficacy trials other reports were obtained reviewed from MEDLINE searches, abstracts professional meetings,...
Identify a group of adults with 'undiagnosed' attention deficit hyperactivity disorder (ADHD) and compare their personal family medical histories, psychosocial profiles, functional impairment quality life non-ADHD controls. Additionally, undiagnosed diagnosed ADHD to investigate possible reasons why the avoid clinical detection.ICD-9 codes for in administrative claims records responses telephone-administered adult screener [the Adult Self-Report Scale (ASRS)] were used classify approximately...
A comprehensive summary of the evidence for validity and reliability Vocational Identity scale is provided period 1980-1992. The authors conclude that has substantial construct retest reliability. Contrary to earlier analyses, a recent large factor analysis strongly suggests best represented by single factor.
Despite increased carotid artery stenting (CAS) dissemination following the 2005 National Coverage Determination, to our knowledge, periprocedural and long-term outcomes have not been described among Medicare beneficiaries.To describe incidence of during after period beneficiaries undergoing CAS.Observational study with a mean follow-up time approximately 2 years 22,516 fee-for-service at least 66 old CAS (2005-2009) who were linked Centers for & Medicaid Services' database. Database...
Article AbstractBackground: This prospective 105-site study was conducted to determine the rate of seizures and other serious adverse experiences associated with therapeutic use sustained-release formulation bupropion (bupropion SR). Method: 3100 patients a DSM-III-R diagnosis depression without current or past an eating disorder no personal family history seizure disorders were treated for up 8 weeks SR in open-label study. Dosing initiated at 50 mg b.i.d. increased maximum 150 unless not...
Article AbstractBackground: A sustained-release formulation of bupropion (bupropion SR), developed with an improved pharmacokinetic profile to permit less frequent dosing than the immediate-release form, has not been evaluated in active comparator trials. This randomized, double-blind, parallel-group trial was conducted compare efficacy and safety SR sertraline. Method: Outpatients moderate severe major depressive disorder (DSM-IV) received (100_300 mg/day) or sertraline (50_200 for 16...
Bupropion is an antidepressant agent that also effective as aid to quit cigarette smoking. A single 150‐mg tablet of sustained‐release bupropion hydrochloride was administered two groups volunteers, smokers and nonsmokers, who were matched for race, gender, body frame, age, weight. Pharmacokinetic parameters calculated bupropion, three major metabolites (hydroxybupropion the aminoalcohol isomers, threohydrobupropion erythrohydrobupropion, expressed a composite total). Mean (±SD) values area...
The objective of this study was to examine the impact co-occurring social and emotional difficulties on missed school days healthcare utilization among children with attention deficit/hyperactivity disorder (ADHD). Data were from 2007 U.S. National Health Interview Survey (NHIS) based parental proxy responses questions in Sample Child Core, which includes demographics, health, treatment, status as measured by about depression, anxiety, phobias, well items brief version Strength Difficulties...