A5072178061- Ferrocene Chemistry and Applications
- Advanced biosensing and bioanalysis techniques
- Parasites and Host Interactions
- Helminth infection and control
- Biopolymer Synthesis and Applications
- Gut microbiota and health
- Metal complexes synthesis and properties
- Research on Leishmaniasis Studies
- Inhalation and Respiratory Drug Delivery
- Molecular Junctions and Nanostructures
- Cancer Mechanisms and Therapy
- Corrosion Behavior and Inhibition
- Nanoparticles: synthesis and applications
- Cancer Research and Treatments
- Probiotics and Fermented Foods
- Parasite Biology and Host Interactions
Université d'Angers
2022-2025
Centre National de la Recherche Scientifique
2020-2025
Inserm
2020-2025
Micro et Nanomédecines translationnelles
2020-2021
Université Bretagne Loire
2020
Chemotherapy currently used for lung cancer treatment often consists in a combination of drugs, with moderate efficacy and severe side effects. A major drawback the classical inorganic drugs...
Abstract Schistosomiasis is a disease of poverty affecting millions people. Praziquantel (PZQ), with its strengths and weaknesses, the only treatment available. We previously reported findings on three lead compounds derived from oxamniquine (OXA), an old antischistosomal drug: ferrocene‐containing (Fc‐CH 2 ‐OXA), ruthenocene‐containing (Rc‐CH ‐OXA) benzene‐containing (Ph‐CH OXA derivatives. These derivatives showed excellent in vitro activity against both Schistosoma mansoni larvae adult...
Schistosomiasis is a disease of poverty affecting millions people. Praziquantel (PZQ), with its strengths and weaknesses, the only treatment available. We previously reported 3 lead compounds derived from oxamniquine (OXA), an old antischistosomal drug: ferrocene‐containing (Fc‐CH2‐OXA), ruthenocene‐containing (Rc‐CH2‐OXA) benzene‐containing (Ph‐CH2‐OXA). These derivatives showed excellent in vitro activity against both Schistosoma mansoni S. haematobium larvae adult worms, vivo mansoni....
<div>Schistosomiasis is a disease of poverty affecting millions people. Praziquantel (PZQ), with its </div><div>strengths and weaknesses, the only treatment available. We previously reported 3 lead </div><div>compounds derived from oxamniquine (OXA), an old antischistosomal drug: ferrocene‐containing </div><div>(Fc‐CH2‐OXA), ruthenocene‐containing (Rc‐CH2‐OXA) benzene‐containing (Ph‐CH2‐OXA). </div><div>These derivatives showed excellent...