A5047129160- Orthopaedic implants and arthroplasty
- Titanium Alloys Microstructure and Properties
- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
- Cancer Immunotherapy and Biomarkers
- Alzheimer's disease research and treatments
- COVID-19 Clinical Research Studies
- Acute Myocardial Infarction Research
- Global Cancer Incidence and Screening
- Vitamin D Research Studies
- Multiple and Secondary Primary Cancers
- Colorectal Cancer Screening and Detection
- Genetics and Plant Breeding
- S100 Proteins and Annexins
- Liver Disease Diagnosis and Treatment
- Soybean genetics and cultivation
- Neuroinflammation and Neurodegeneration Mechanisms
- Agronomic Practices and Intercropping Systems
- Genetic factors in colorectal cancer
- Cancer Diagnosis and Treatment
- Hydrogen embrittlement and corrosion behaviors in metals
- Cardiac, Anesthesia and Surgical Outcomes
- Metal and Thin Film Mechanics
- COVID-19 Impact on Reproduction
- Cardiac Arrest and Resuscitation
Khyber Medical College
2021-2024
Hayatabad Medical Complex
2024
University of Oklahoma Health Sciences Center
2020-2022
University of Liverpool
1975-2021
Royal Berkshire NHS Foundation Trust
2020
Women with colorectal cancer (CRC) have a significant survival advantage over men. Sex influences on the tumour microenvironment (TME) are not well characterised, despite importance of immune response in CRC. We hypothesised that sex-divergent responses could contribute to survival.Using murine model metastatic CRC, we examined T cells, macrophages, and cytokines locally systemically. TME serum were measured by multiplex bead-based arrays, while FCA was used identify cells phenotypes. IHC...
Women with colorectal cancer (CRC) have survival advantages over men, yet the underlying mechanisms are unclear. T cell infiltration within CRC tumor microenvironment (TME) correlates strongly survival. We hypothesized that women increased and differential gene expression in TME compared to men. Tissue microarrays comprising primary tumor, infiltrated lymph nodes, uninvolved colon were created from patients. Proportions of CD4 positive (CD4+) CD8 (CD8+) cells identified using...
Background More alarming than the rise of cancer globally is its discreet changing profiles over years. According to our knowledge, no new studies on have taken place in Dir since 2004. Hence, we aimed provide and analyze trends district Dir, Malakand division, Khyber Pakhtunkhwa (KPK), regarding prevalence incidence, compare it nationally internationally. Methods A retrospective study was conducted by collecting data from 2647 clinically diagnosed patients all ages between years 2008 2017,...
Synchronous primary malignancies are a rare finding which can be difficult to diagnose. We present the case of 57-year-old patient with high prostate specific antigen who was found have cancer on subsequent magnetic resonance imaging. A skeletal metastasis also identified at time, although no osteoblastic activity or sclerosis scintigraphy computed tomography, respectively. The started hormonal therapy and follow-up imaging revealed reduced in volume. Despite this, appeared unchanged an...
The aim of the present review is to provide basic knowledge about role tumour necrosis factor-α 1 and tumor receptor 2 in neuro-inflammation diseases. We performed an open-ended, English restricted search PubMed, Embase, PsychINFO, Web Science, Scopus, Cochrane Library for available literature from 24Feb. 2018–12 May 2021, using terms related neuroinflammation, factor-α, factor II (TNFR-II), TNF-α diseases, TNFR-II inflammation-related their relationships, polymorphism. main outcomes...