A5100365388- Circular RNAs in diseases
- Extracellular vesicles in disease
- MicroRNA in disease regulation
- Carbohydrate Chemistry and Synthesis
- Sarcoma Diagnosis and Treatment
- Digital Mental Health Interventions
- Muscle Physiology and Disorders
- Chemical Synthesis and Analysis
- Autophagy in Disease and Therapy
- Polyamine Metabolism and Applications
Chinese University of Hong Kong, Shenzhen
2024
Hubei University of Chinese Medicine
2021
Shanghai Research Institute of Chemical Industry
2020
Harbin Medical University
2019-2020
Fudan University
2020
Clear cell renal carcinoma (CCRCC) is characterized by a highly metastatic potential. The stromal communication between stem cells and cancer critically influences dissemination of cells.The effect exosomes isolated from (CSCs) CCRCC patients on the progress epithelial-mesenchymal transition (EMT) lung metastasis were examined.CSCs promoted proliferation accelerated EMT. Bioactive miR-19b-3p transmitted to CSC induced EMT via repressing expression PTEN. CSCs derived with produced strongest...
(S)-1-(4-Methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline [(S)-1-(4-methoxybenzyl)-OHIQ, (S)-1a] is a key synthetic intermediate in the industrial production of dextromethorphan, one most widely used over-the-counter antitussives. We report here that new cyclohexylamine oxidase discovered by genome mining, named CHAOCCH12-C2, was able to completely deracemize 100 mM 1a under Turner's deracemization conditions afford (S)-1a 80% isolated yield and 99% ee at semipreparative scale (0.4...
Objective: The incidence of skin squamous cell carcinoma (SSCC) has recently been increasing, with diverse clinical manifestations.SSCC could metastasize to lymph nodes or other organs, posing a great threat life. present study was designed investigate the function and underlying mechanism muscleblind-like protein 1 (MBNL1) in carcinoma. Methods: SCL-1 used for vitro model transfected MBNL1 siMBNL1 plasmids. MTT Assays, LDH activity ELISA, Transwell chamber migration experiment were confirm...