- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Retinal and Optic Conditions
- Glaucoma and retinal disorders
- Antioxidant Activity and Oxidative Stress
- Advanced Glycation End Products research
- Retinal Development and Disorders
- Diabetes and associated disorders
- Retinal and Macular Surgery
- Genetic and Kidney Cyst Diseases
- Autoimmune Neurological Disorders and Treatments
- Extracellular vesicles in disease
- Cerebrovascular and genetic disorders
- Blood Pressure and Hypertension Studies
- Corneal Surgery and Treatments
- Traumatic Ocular and Foreign Body Injuries
- Ophthalmology and Visual Health Research
- Heme Oxygenase-1 and Carbon Monoxide
- Economic Zones and Regional Development
- Drug-Induced Ocular Toxicity
- Neuroinflammation and Neurodegeneration Mechanisms
- Intraocular Surgery and Lenses
- MicroRNA in disease regulation
- Pancreatic function and diabetes
- Retinoids in leukemia and cellular processes
Centro Hospitalar de Entre o Douro e Vouga E.P.E.
2014-2025
University of Lisbon
2024
Creative Commons
2024
Centro Hospitalar Lisboa Norte
2024
Universitat de València
2016-2018
Hospital Universitario Reina Sofía
2016
Hospital Universitari i Politècnic La Fe
2016
Hospital Reina Sofía de Murcia
2016
Association for Innovation and Biomedical Research on Light and Image
2003-2011
University of Coimbra
2005
<i>Purpose:</i> To examine the relationship between microaneurysm turnover (formation rate), using a new semi-automatic method (MA-Tracker) based on color fundus photographs, and diabetic retinopathy (DR) progression to clinically significant macular edema (CSME). <i>Methods:</i> In total, 113 patients/eyes with nonproliferative DR (NPDR) were followed up every 6 months for 2 years as controls of clinical trials, by conventional general ophthalmological care next 8...
Abstract Purpose Retinitis pigmentosa (RP) comprises a genetically and clinically heterogeneous group of inherited retinal degenerations, where 20–30% patients exhibit extra-ocular manifestations (syndromic RP). Understanding the genetic profile RP has important implications for disease prognosis counseling. This study aimed to characterize syndromic in Portugal. Methods Multicenter, retrospective cohort study. Six Portuguese healthcare providers identified with clinical diagnosis available...
To compare the efficacy of 3 different artificial tears (AT) acting primarily in one tear film layers (Tears Again®, lipidic; Opticol®, aqueous; Optive®, mucin) recovering changes patients with dry eye symptoms due to external causes.A total 27 patients, associated extra hours computer or contact lenses use, were randomized 4 treatment groups: A received Tears Again®; B Optive®; C Opticol®; D no (control). Patients observed visits: day 0, 7, and 30. Tear break-up time (TBUT) Schirmer tests...
Reactive oxygen species (ROS) overproduction and ROS-signaling pathways activation attack the eyes. We evaluated oxidative stress (OS) effects of a daily, core nutritional supplement regimen containing antioxidants omega 3 fatty acids (A/ω3) in type 2 diabetics (T2DM). A case-control study was carried out 480 participants [287 T2DM patients with (+)/without (-) diabetic retinopathy (DR) 193 healthy controls (CG)], randomly assigned to daily pill A/ω3. Periodic evaluation through 38 months...
We report a case of 54-year-old woman presented at the emergency service with complaints transitory visual obscurations for four days, and headache, nausea occasional vomiting in last two months. She had been diagnosed colorectal cancer one year ago she was on treatment oxaliplatin FOLFOX schedule. On ophthalmic examination, vision 20/20 both eyes bilateral disc swelling noted. The neurologic examination normal. Magnetic resonance revealed no changes. A diagnostic lumbar puncture...
Abstract Purpose: To highlight the high positive predictive value of retinal pigmentary epithelium (RPE) irregularity and shallow irregular pigmented elevation (SIRE) sign in identifying nonexudative neovascular membranes underscore usefulness these signs clinical practice. Methods: Retrospective case series analysis conducted medical retina clinic one center. Results: Seven cases patients with confirmed optical coherence tomography angiography (OCTA) imaging where RPE and/or SIRE had been...
Purpose With the increasing interest in choroidal changes Diabetes, we performed a pilot and prospective study to evaluate morphological findings diabetic macular edema detected with SD-OCT, compared normal or non-macular eyes. Methods Two groups of patient were selected: Diabetic patients no any stage retinopathy history ocular treatment; non-diabetic as controls. Patients other diseases surgery where not included. Complete ophthalmological exam was performed. A retinography, blood pressure...
Introduction: Idiopatic Macular Telangiectasia (IMT) are a rare group of various entities presenting with incompetence, ectasia and/or irregular dilations the juxtafoveolar capillaries one or both eyes. Case Report: A 62 year old female Glaucoma was sent to Retina Department suspected diagnosis retinal vein occlusion on left eye (LE). Her best corrected visual acuity (BCVA) 20/20 in right (RE) and 20/25 LE. Slit lamp examination normal; fundoscopy showed cup-to-disc relation 0.6 RE normal...