Alexandra Dădârlat‐Pop

ORCID: 0000-0003-3964-6995
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About
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Research Areas
  • Cardiovascular Function and Risk Factors
  • Cardiac Imaging and Diagnostics
  • Acute Myocardial Infarction Research
  • Cardiac Valve Diseases and Treatments
  • Infective Endocarditis Diagnosis and Management
  • Coronary Interventions and Diagnostics
  • Cardiovascular Disease and Adiposity
  • Cardiac tumors and thrombi
  • Sarcoma Diagnosis and Treatment
  • Aortic Disease and Treatment Approaches
  • Heart Failure Treatment and Management
  • Cardiac pacing and defibrillation studies
  • Vascular anomalies and interventions
  • Cardiac Health and Mental Health
  • Vascular Procedures and Complications
  • Cardiovascular Effects of Exercise
  • Cardiovascular and exercise physiology
  • Cardiac Structural Anomalies and Repair
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • GDF15 and Related Biomarkers
  • Coronary Artery Anomalies
  • Eosinophilic Disorders and Syndromes
  • Vascular Malformations and Hemangiomas
  • Dental Anxiety and Anesthesia Techniques
  • Biomarkers in Disease Mechanisms

Iuliu Hațieganu University of Medicine and Pharmacy
2020-2025

Institute of Cardiology
2024

Faculty (United Kingdom)
2024

Spitalul Clinic Județean de Urgență Cluj-Napoca
2022-2023

Abstract Background Embolic events are a severe complication of infective endocarditis (IE). Understanding the role sex differences in embolic risk and associated predictors may improve patient stratification management. Methods A total 137 patients with IE (47 women, 90 men) were retrospectively included study. All underwent comprehensive clinical evaluation, including ECG, transthoracic transesophageal echocardiography, full-body CT imaging to identify events. Pathogenic agents also...

10.1093/eurjpc/zwaf236.096 article EN European Journal of Preventive Cardiology 2025-05-01

Background and Purpose: In Romania, robust data about the prevalence of obesity heart failure are lacking, especially in elderly; therefore, this study aims to analyze profile overweight obese patients aged > 65 years admitted a Romanian hospital for worsening failure, also their risk presence comorbidities. Patients Methods: This cross-sectional was conducted 126 consecutive elderly with failure. They were divided into three groups: reduced (< 40%) – HFrEF, mid-range (40– 49%) HFmrEF...

10.2147/cia.s248158 article EN cc-by-nc Clinical Interventions in Aging 2020-04-01

Cardiac tumors are a very rare but heterogenous group of diseases that may reveal themselves through variety nonspecific cardiac symptoms pose challenge to the diagnostic process. Myxofibrosarcoma is particularly type tumor carries poor prognosis, thus making accurate and timely diagnosis essential. A 61-year-old woman presented with fatigue shortness breath during mild exercise, have progressively worsened previous year. Multimodality imaging consisting transthoracic transesophageal...

10.3390/diagnostics13101811 article EN cc-by Diagnostics 2023-05-20

Dental erosion is a significant topic in medical literature, both for gastroenterology and dental medicine. structure loss has psychosocial functional significance. The pathogenesis of patients diagnosed with gastroesophageal reflux disease (GERD) characterized by the presence an acidic oral environment after episodes, not well understood. present study was designed to observe effect low pH time on natural surfaces including enamel dentine, but also materials used treating these destructions...

10.3892/etm.2021.10105 article EN Experimental and Therapeutic Medicine 2021-04-23

To determine the relationship between myocardial work (MW) indices derived from non-invasive pressure-strain loops (PSL) and established parameters of left ventricular (LV) performance in patients with acute infarction (AMI) heart failure (HF) preserved or mid-range ejection fraction (HFpEF/HFmrEF).Speckle-tracking echocardiography (STE) was used to MW global longitudinal strain (GLS) first 24-48 hours after admission AMI, HF symptoms, NT-proBNP >300 pg/mL (LVEF) >40%. calculated by using...

10.11152/mu-2672 article EN Medical Ultrasonography 2020-10-20

We report a case of 52-year-old woman who was referred to our institution with superior vena cava syndrome and investigated through echocardiography, CT MRI revealing well-defined, encapsulated pericardial mass. The pathology, correlated the immunohistochemical analysis, concluded it an extremely rare primary synovial sarcoma. patient underwent surgery chemotherapy 16-month disease-free survival passed away after contralateral aggressive relapse. Moreover, we discuss role each imaging...

10.3390/diagnostics12010158 article EN cc-by Diagnostics 2022-01-10

Background: Hemodynamically significant unprotected left main (LM) coronary artery disease is a high-risk clinical condition because of the large area myocardium at risk, and it requires prompt revascularization. Percutaneous intervention (PCI) an appropriate alternative to bypass grafting (CABG) for revascularization LM in patients with low-to-intermediate anatomic complexity or when patient refuses CABG after adequate counseling by heart team. Methods: We retrospectively evaluated 201...

10.3390/diagnostics13071333 article EN cc-by Diagnostics 2023-04-03

Pseudomonas aeruginosa is a rare yet particularly aggressive infective endocarditis pathogen. We describe case of successfully managed double-valve P. endocarditis, in which the presumed source bacteremia was long-term tunneled central venous catheter used for hemodialysis.

10.3390/ijms231911127 article EN International Journal of Molecular Sciences 2022-09-22

Background: Previous studies have demonstrated a direct correlation between pacemaker programming mode and exercise capacity on long-term follow-up. In the present study we aimed to test whether reprogramming of can produce immediate effects patients' capacity. Methods: The 33 patients wearing dual-chamber pacemakers was evaluated by cardiopulmonary at 24-hour intervals in two modes: initially single-chamber ventricular pacing with fixed 60bpm rate, second phase dual chamber adaptable up...

10.12680/10.12680/balneo.2023.577 article EN cc-by-nc-nd Balneo and PRM Research Journal 2023-09-01

Background: Transcatheter aortic valve replacement (TAVR) became the leading therapeutic strategy for in older patients with severe symptomatic stenosis. Echocardiographic parameters that mark left ventricle and right reverse remodeling after TAVR are not well established. The aim of current study is to describe dynamics both (LV) (RV) strain derived from speckle tracking echocardiography elderly at 3-months procedure. Methods: We enrolled 52 consecutive (77 ± 4.9 years old, median STS score...

10.2147/cia.s413426 article EN cc-by-nc Clinical Interventions in Aging 2023-09-01

Leptin, one of the best-known adipocytes, together with renin-angiotensin-aldosterone system and galectin-3 are important players in inflammation, arterial hypertension heart failure pathophysiology. Moreover, uninucleotide A1166C polymorphism is associated poor prognosis failure. The aim study was to investigate a possible relationship between leptin serum values, specific biomarkers presence AT1 receptor overweight obese patients.The included 88 consecutive patients admitted for...

10.2147/ijgm.s301285 article EN cc-by-nc International Journal of General Medicine 2021-05-01

Left bundle branch block is not a benign pathology, and its presence requires the identification of pathological substrate, such as ischemic heart disease. appears to be more commonly associated with normal coronary arteries, especially in women. The objectives our study were describe particularities left women compared men Result: We included seventy patients disease, mean age 67.01 ± 8.89 years. There no differences profile risk factors, except for smoking uric acid. ventricular...

10.3390/jcm10112284 article EN Journal of Clinical Medicine 2021-05-25

Background: Stent enhancement techniques allow adequate visualization of stent deformation or incomplete expansion at the ostium side branch. Measuring branch length (SESBL) could reflect procedural success in terms optimal and apposition with better long-term outcomes. A longer SESBL may a polygon confluence (SB) ostium. Methods: We evaluated 162 patients receiving left main (LM) provisional one-stent technique measured SESBL, dividing them into two groups: SESBL≤ 2.0 mm &gt; mm. Results:...

10.3390/jpm13050791 article EN Journal of Personalized Medicine 2023-05-03

Abstract Introduction This study aimed to assess the significance of left atrial (LA) strain in patients with persistent fibrillation (AF), undergoing electrical cardioversion (ECV) and investigate their predictive value determining AF recurrence (AFR) at 2-years. Material methods 60 who were admitted for a duration less than 12 months prospectively included. Echocardiography was performed all prior ECV repeated seven days during sinus rhythm (SR). Every patient underwent periodic follow-up...

10.1093/eurjpc/zwae175.005 article EN other-oa European Journal of Preventive Cardiology 2024-06-01

There is clear evidence of a significant reduction in all major cardiovascular adverse events (MACE) by coronary artery bypass grafting (CABG) left main stenosis (LMCS), but revascularization percutaneous intervention (PCI) shows an increasingly important role as alternative to CABG. Several recent trials aiming test the difference mortality between two types found conflicting data. The aim this study determine whether PCI non-inferior CABG with respect occurrence MACE at 1 year patients...

10.3390/life12030347 article EN cc-by Life 2022-02-27

Anomalous left coronary artery from the pulmonary (ALCAPA) syndrome is a rare congenital anomaly, which can cause potentially fatal complications, such as heart failure, myocardial infarction and sudden cardiac death. Only few patients untreated survive to adulthood. We highlight importance of multimodal imaging in diagnosis ALCAPA young asymptomatic female patient with inducible ischemia on exercise. The was successfully treated surgery

10.11152/mu-2325 article EN Medical Ultrasonography 2020-02-19
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