A5018973184- Medical Imaging Techniques and Applications
- Cancer, Hypoxia, and Metabolism
- Glioma Diagnosis and Treatment
- Advanced MRI Techniques and Applications
- Cerebrovascular and Carotid Artery Diseases
- Nutritional Studies and Diet
- Cardiovascular Health and Disease Prevention
- Lanthanide and Transition Metal Complexes
- Edible Oils Quality and Analysis
- Meat and Animal Product Quality
- Cardiac Imaging and Diagnostics
- Medical Image Segmentation Techniques
- Cardiovascular Disease and Adiposity
Université de Sherbrooke
2017-2024
Aging is an important risk factor for cardiovascular diseases and convincing data have shown that chronic low-grade inflammation, which develops with advanced age, contributes significantly to risk. The present study aimed use 18F-FDG/18F-NaF-PET/CT imaging to, respectively, gauge arterial inflammation microcalcification in a healthy elderly population assess the potential benefits of tyrosol- hydroxytyrosol-rich diet on these two markers atherosclerotic plaque fragility. Eleven participants...
Aim: The purpose of this study was to locate the levels hypoxia in glioblastoma PET images measured with 18F-fluoromisonidazole human subjects. It is recognized that tumors are resistant treatment by radiotherapy and chemotherapy. Methods: were acquired dynamic mode for 15 min or 30 static two single scans at 2 h 3 allow accumulation radiotracer tumor. analyzed voxel basis compartmental analysis (CA) usual tumor-to-blood uptake ratio (TBR). Kmeans algorithm applied cluster images. Results:...
Tumor hypoxia is defined as the reduction of oxygen supply to tumor cells. Glioblastoma (GBM) tumors are characterized by high levels hypoxia, which results in poor prognosis even after treatment radiotherapy and chemotherapy. The most current technique used for imaging GBM 18F-Fluoromisonidazole (18F-FMISO) with PET imaging. aim this study decompose dynamic 18F-FMISO images tissue components spatial distribution over time. scanning protocol begins 15 or 30 minutes brain followed static at 2...
18F-fluoromisonidazole (18F-FMISO) is the most extensively used Positron Emission Tomography (PET) hypoxia biomarker. Uptake of 18F-FMISO by tumors provides a quantitative map hypoxia, which can be for dose escalation in radiotherapy. Several techniques have been developed to quantify and delineate tumor volumes such as tumor-to-blood ratio (TBR), tumor-to-normal tissue (TNR) compartmental modeling approaches. This study aims report analyzes aiming at delineating tumors. Scanning protocols...
We present in this study a semi-automatic procedure to segment artery PET images elderly subjects with atherosclerosis. The inflammation the is precursor of atheromatous plaque detachment and obstruction blood vessels brain or heart. CT allow calcification detection arteries, dynamic 18F-FDG calculate glucose metabolism arteries ultimately detect inflammation. goal image segmentation was correlate on images. First, all were delineated each slice non-enhanced reference anatomic atlases, we...
Glioblastoma Multiform (GBM) is the most aggressive tumor in brain. The characterized by extremely rapid growth, hypoxia (reduced availability of oxygen) and necrosis. This study aimed to determine best optimal time (or minimal time) for 18F-FMISO PET single scan imaging with help spectral analysis (SA). Imaging protocols involved a 15 min dynamic followed 10 static scans at 2 h, 3 4 h order allow uptake 18F- FMISO tumors. We applied SA decompose images into their essential components...
Positron Emission Tomography (PET) imaging with 11C-Acetate (ACE) is regularly used in cardiovascular and cancer imaging. In the earlier stages of ACE developments, it has been mainly for hepatocellular carcinoma, prostate cancer, myocardial oxygen consumption. The previous studies compared advantage 18F-Fluorodeoxyglucose (18F-FDG) using Standard Uptake Value (SUV) tissue-to-blood ratio (TBR) method. current study proposes application dynamic PET monitoring early response to treatment. We...