A5100444284- Rheumatoid Arthritis Research and Therapies
- Oral microbiology and periodontitis research
- Oral Health Pathology and Treatment
- Spondyloarthritis Studies and Treatments
- Advanced Proteomics Techniques and Applications
- Biosimilars and Bioanalytical Methods
- Systemic Sclerosis and Related Diseases
- Immune Cell Function and Interaction
- Biosensors and Analytical Detection
- T-cell and B-cell Immunology
- CAR-T cell therapy research
Cheongju University
2020
Seoul National University
2016-2020
Novilytic (United States)
2013
Hanyang University
2011
A rapid plasma extraction technology that collects a 2.5 μL aliquot of within three minutes from finger-stick derived drop blood was evaluated. The utility the cards used paper collection disc bearing produced could be air-dried in fifteen and placed mailing envelop for transport to an analytical laboratory. This circumvents need venipuncture specialized vials by phlebotomist along with centrifugation refrigerated storage. Plasma achieved applying membrane stack through which drawn capillary...
A cross-sectional study was undertaken to investigate the association between severity of periodontitis and clinical manifestation rheumatoid arthritis (RA).Two hundred sixty-four RA patients 88 age- sex-matched controls underwent dental exam. Additionally, manifestations including disease activity anti-citrullinated protein antibodies were evaluated in patients.The prevalence moderate or severe higher compared (63.6% vs 34.1%, p < 0.001). In markers periodontal inflammation, bleeding on...
Purpose: Periodontitis and rheumatoid arthritis (RA) share a similar inflammatory pathogenesis.Porphyromonas gingivalis (Pg) can induce anticyclic-citrullinated peptide autoantibodies (anti-CCP antibodies), key factor in the development of RA.This study aimed at evaluating relationships between 2 diseases identifying clinical implications thereof, with focus on periodontal pathogens Korean adults.Methods: A total 260 RA patients 86 age-and sex-matched control without were enrolled this...
Effector memory (EM) CD8+ T cells expressing lower levels of IL-7R α (IL-7Rαlow) from healthy individuals are partly compromised in vitro, but the identity these has remained unclear. In this study, we demonstrate that human IL-7Rαlow EM naturally occurring anergic vivo and impaired proliferation IL-2 production competent IFN-γ TNF-α production, a state can be restored by stimulation. show decreased expression GATA3 c-MYC defective metabolic reprogramming toward glycolysis, process required...