- Asthma and respiratory diseases
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Allergic Rhinitis and Sensitization
- Lipoproteins and Cardiovascular Health
- Dermatology and Skin Diseases
- Immune Cell Function and Interaction
- IL-33, ST2, and ILC Pathways
- Systemic Lupus Erythematosus Research
- Liver Disease Diagnosis and Treatment
- Respiratory and Cough-Related Research
- Cancer, Lipids, and Metabolism
- Food Allergy and Anaphylaxis Research
- Immune Response and Inflammation
- Dialysis and Renal Disease Management
- Blood Pressure and Hypertension Studies
- T-cell and B-cell Immunology
- Monoclonal and Polyclonal Antibodies Research
- Metabolism and Genetic Disorders
- Chronic Kidney Disease and Diabetes
- Neonatal Respiratory Health Research
- Pharmacological Effects of Natural Compounds
- Chemokine receptors and signaling
- Pharmacological Effects and Toxicity Studies
- Diabetes Treatment and Management
- Mercury impact and mitigation studies
Tulane University
2025
University of Alabama at Birmingham
2024
Macau University of Science and Technology
2013-2023
Hospital for Sick Children
2023
University of Kansas Medical Center
2022
University of Kansas
2022
Stantec (Canada)
2022
John Hunter Children's Hospital
2022
Quality Research
2012-2019
Victoria College
2018
To report the clinical features of anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis in patients < or = 18 years old.Information was obtained by authors referring physicians. Antibodies were determined immunocytochemistry and enzyme-linked immunosorbent assay (ELISA) using HEK293 cells ectopically expressing NR1.Over an 8-month period, 81 (12 male) with anti-NMDAR identified. Thirty-two (40%) =18 old (youngest 23 months, median 14 years); 6 male. The frequency ovarian teratomas 56%...
Abstract The ever‐increasing demand for large‐scale energy storage systems requires novel battery technologies with low‐cost and sustainable properties. Due to earth‐abundance cost effectiveness, the development of rechargeable potassium ion batteries (PIBs) has recently attracted much attention. Since carbon‐based materials are abundant, inexpensive, nontoxic, safe, extensive feasibility investigations have suggested that they can become promising anode PIBs. This review not only attempts...
The prevalence of obesity in both adults and children is increasing rapidly. Obesity independently associated with arterial endothelial dysfunction wall thickening, key early events atherogenesis that precede plaque formation.To evaluate the reversibility obesity-related carotid intima-media thickening by dietary and/or exercise intervention programs, 82 overweight (body mass index, 25+/-3), 9 to 12 years age, were randomly assigned modification only or diet plus a supervised structured...
Objective. To assess the effectiveness of a “stress dose” hydrocortisone for rescue treatment refractory hypotension and adrenocortical insufficiency prematurity in very low birth weight (VLBW) infants. We hypothesized that significantly more VLBW infants who were receiving dopamine ≥10 μg/kg per min could wean off vasopressor support 72 hours after with hydrocortisone. Methods. A double-blind, randomized, controlled study was conducted university neonatal center. Forty-eight had required...
Thymic stromal lymphopoietin (TSLP) is highly expressed by bronchial epithelial cells and skin keratinocytes in allergic diseases. TSLP acts as a master switch for inflammation through the activation of dendritic mast initiating inflammatory type 2 T-helper lymphocyte responses. To elucidate immunological cascades epithelium/keratinocyte-eosinophil-mediated inflammation, we examined modulating effects on human eosinophils. Expression receptor complex was detected RT-PCR, flow cytometry,...
OBJECTIVE—Chronic kidney disease (CKD) predicts cardiovascular (CVD) in the general population. We investigated effects of stages renal function using estimated glomerular filtration rate (eGFR) on all-cause mortality and end points a prospective cohort Chinese type 2 diabetic patients. RESEARCH DESIGN AND METHODS—Between 1995 2000, 4,421 patients without macrovascular or end-stage were recruited. Renal was assessed by eGFR, as calculated abbreviated Modification Diet Disease Study Group...
IL-17A and IL-17F are members of the IL-17 family that play crucial roles in allergic inflammation. Recent studies reported production from a distinct Th lymphocyte subset, Th17, was specifically induced by IL-23, which produced dendritic cells macrophages response to microbial stimuli. The IL-23-IL-17 axis might therefore provide link between infections diseases. In present study, we investigated effects IL-17A, IL-17F, alone or combination, on cytokine chemokine release eosinophils...
• Fasting serum glucose, glycosylated hemoglobin, and fructosamine concentrations were determined in 304 consecutive subjects admitted with acute stroke, within 48 hours of ictus. Based on the medical history these results, divided into known diabetics, newly diagnosed stress hyperglycemia, nondiabetics. The type stroke was classified as lacunar infarct, cerebral or intracerebral hemorrhage, based clinical examination by a neurologist computed tomographic brain scan and/or autopsy. Immediate...
Activation of eosinophils by microbe-derived molecules via Toll-like receptors (TLR) potentially provides the link between microbe-induced innate immune responses and exacerbation allergic inflammation. We investigated expression TLRs effect their ligands on human eosinophils. Expression TLR1-9 was detected Western blot flow cytometry. Adhesion molecules, cytokines, superoxides, eosinophlilic cationic protein (ECP) were assessed cytometry, enzyme-linked immunosorbent assay, chemiluminescent...
Atopic dermatitis (AD) is a common allergic skin disease, characterized by dryness, itchiness, thickening and inflammation of the skin. Infiltration eosinophils into dermal layer presence edema are typical characteristics in biopsy AD patients. Previous vitro clinical studies showed that Pentaherbs formula (PHF) consisting five traditional Chinese herbal medicines, Flos Lonicerae, Herba Menthae, Cortex Phellodendri, Moutan Rhizoma Atractylodis at w/w ratio 2:1:2:2:2 exhibited therapeutic...