A5092725612- Migraine and Headache Studies
- Vagus Nerve Stimulation Research
- Barrier Structure and Function Studies
- Adenosine and Purinergic Signaling
- S100 Proteins and Annexins
- Heart Rate Variability and Autonomic Control
- interferon and immune responses
- Virus-based gene therapy research
- Olfactory and Sensory Function Studies
- Gastrointestinal motility and disorders
- Pain Mechanisms and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Salivary Gland Disorders and Functions
- Complementary and Alternative Medicine Studies
- Infant Health and Development
- Gut microbiota and health
- Obsessive-Compulsive Spectrum Disorders
Gazi University
2023-2024
Medication overuse headache (MOH) was recently shown to be associated with leaky gut in rodents. We aimed investigate whether chronic migraine (CM) patients MOH have elevated lipopolysaccharide levels and inflammatory molecules blood circulation.
Medication overuse is common among chronic migraine patients and nonsteroidal antiinflammatory drugs (NSAIDs)are the most frequently overused drugs. The pathophysiological mechanisms underlying medication headache (MOH) are notcompletely understood. Intestinal hyperpermeability leaky gut reported in using NSAIDs. aim of study toinvestigate role inflammation an MOH model male rats.Methods: was conducted Sprague Dawley rats. There were two experimental groups. first group chronicNSAID which...
Abstract Objective Medication overuse headache (MOH) is a secondary that accompanies chronic migraine. Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most frequently used analgesics worldwide and they known to induce leaky gut. In this study, we aimed investigate whether NSAID induced MOH associated with altered circulating lipopolysaccharide binding protein (LBP) levels inflammatory molecules. Materials methods Piroxicam (10 mg/kg/day, po) for 5 weeks was in female Sprague Dawley...
Chronic migraine (CM) patients with medication overuse headache (MOH) were recently shown to be associated leaky gut and inflammation. We aimed investigate microbiota profiles of CM MOH, their correlations inflammatory serum parameters, food triggers, comorbid anxiety depression.
Abstract Objective: Medication overuse headache (MOH) is secondary that accompanies chronic migraine and NSAIDs are the most frequently use analgesics in word. known to induce leaky gut we aimed investigate whether NSAID induced MOH associated with altered circulating LBP levels inflammatory molecules. Materials Methods: Piroxicam (10 mg /kg, po) for 5 weeks was used female Sprague Dawley rats. Pain tested by evaluating periorbital von Frey thresholds, grooming, freezing headshake behavior....
In both normal and pathological situations, the brain gut communicate. Intestinal inflammation is crucial in progression of systemic neuroinflammation. Inflammatory Bowel Diseases, neurodegeneration, neuroinflammation all benefit from elucidating molecular relationships between brain. Crohn’s disease, ulcerative colitis, indeterminate colitis are chronic disorders characterized by recurring episodes gastrointestinal inflammation. bowel disease has evolved into a global 21st century,...
Autism is a neurodevelopmental disorder with limited treatment alternatives and which incidence increasing. Some research suggests that vagus nerve simulation might lead to the reduction of certain symptom. Therefore, we aimed examine effect bilateral transcutaneous auricular stimulation (tVNS) on inflammatory response in an adult valproic acid (VPA) induced mouse (C57BL6) model autism for first time. The was by oral VPA administration (600 mg·kg −1 ) C57BL/6 pregnant mice E12.5 days. study...