A5103004228- Lung Cancer Research Studies
- Colorectal and Anal Carcinomas
- Neuroendocrine Tumor Research Advances
- Salivary Gland Tumors Diagnosis and Treatment
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Viral-associated cancers and disorders
- Lymphadenopathy Diagnosis and Analysis
- Gastrointestinal disorders and treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- IgG4-Related and Inflammatory Diseases
- Cancer Genomics and Diagnostics
- Hydrocarbon exploration and reservoir analysis
- Cutaneous lymphoproliferative disorders research
- Gallbladder and Bile Duct Disorders
- Gastrointestinal Tumor Research and Treatment
- PI3K/AKT/mTOR signaling in cancer
- Cancer, Lipids, and Metabolism
- Pancreatic and Hepatic Oncology Research
- Ferroptosis and cancer prognosis
- Phytochemical compounds biological activities
- Medical Imaging and Pathology Studies
- CNS Lymphoma Diagnosis and Treatment
- Inflammatory Myopathies and Dermatomyositis
- Bladder and Urothelial Cancer Treatments
- Geological formations and processes
Soochow University
2025
Soochow University
2025
Fudan University Shanghai Cancer Center
2024-2025
Shanghai Medical College of Fudan University
2024-2025
Fudan University
2015-2024
Wuhan University
2024
Renmin Hospital of Wuhan University
2024
National Institute for Occupational Health and Poison Control
2024
Chinese Center For Disease Control and Prevention
2024
ProQuest (United States)
2023
EIF5A2, eukaryotic translation initiation factor 5A2, is associated with several human cancers. In this study, we investigated the role of EIF5A2 in metastatic potential localised invasive bladder cancer (BC) and its underlying molecular mechanisms were explored. The expression pattern BC was determined by immunohistochemistry. addition, function elucidated a series vitro vivo assays. Overexpression an independent predictor for poor metastasis-free survival patients treated radical...
Long-term exposure to lead (Pb) can result in chronic damage the body through accumulation central nervous system (CNS) leading neurodegenerative diseases, such as Alzheimer’s disease (AD). This study delves into intricate role of miR-671/CDR1as regulation etiology AD-like lesions triggered by Pb adult mice. To emulate effects Pb, we established a rodent model spanning 10 months controlled administration, dividing 52 C57BL/6J mice groups receiving varying concentrations (1, 2, or 4 g/L)...
Inactivation of p53 by mutations commonly occurs in human cancer. The mutated proteins may escape proteolytic degradation and exhibit high expression tumors acquire gain-of-function activity that promotes tumor progression chemo-resistance. Therefore, selectively targeting the mutants serve as a promising therapeutic strategy for cancer prevention treatment. In this study, we identified cabozantinib, multikinase inhibitor currently used clinical treatment several types cancer, selective...
Background: Ferroptosis plays a vital role in cancer development and treatment. The relationship between ferroptosis-related genes breast prognosis, as well immunotherapy outcomes, remains unknown. Objectives: To evaluate the prognostic value of cancer. Methods: We conducted differential expressions analysis for on public databases patients our center analyzed their predictive patients. Results: identified genes, constructed nomogram, validated key using patient data from center. also...
The aim of this study was to assess the correlation sperm morphology with intrauterine insemination (IUI) outcome in patients normal concentration and motility. About 412 couples who underwent 908 IUI cycles were involved present study. A total 110 clinical pregnancies achieved a pregnancy rate 12.11% per cycle. rates cycle 7.60%, 12.67%, 13.62% 13.13% <5%, 5-9%, 10-14% >14% forms, respectively. lowest (7.60%) obtained group forms below 5%. However, not significantly different from other...
This prospective, two-cohort phase 2 trial with random allocation was conducted to evaluate the safety and efficacy of neoadjuvant tislelizumab combined nab-paclitaxel/paclitaxel cisplatin (TP) in patients esophageal squamous cell carcinoma (ESCC). Patients were enrolled randomly assigned nab-paclitaxel or paclitaxel cohorts at a 1:1 ratio, received intravenous (200 mg, day 1) (25 mg/m
Abstract Background Obesity paradox in heart failure (HF) is defined as better outcomes associated with higher body mass index (BMI). Purpose We explored the relationship between BMI and cardiogenic shock (CS) due to acute myocardial infarction. Methods The Cardiogenic Shock Working Group (CSWG) registry includes patients CS, regardless of etiology, from 17 clinical sites across USA. In- hospital mortality, a main outcome measure, was analyzed depending on continuous variable, well quartiles...