A5072706776- RNA Interference and Gene Delivery
- Dendrimers and Hyperbranched Polymers
- Nanoparticle-Based Drug Delivery
- Computational Drug Discovery Methods
- Nanoplatforms for cancer theranostics
- Lipid Membrane Structure and Behavior
- Cancer, Lipids, and Metabolism
- Advanced Polymer Synthesis and Characterization
- Plant-based Medicinal Research
- Analytical Chemistry and Chromatography
- Cell Adhesion Molecules Research
- Melanoma and MAPK Pathways
- Polymer Nanocomposite Synthesis and Irradiation
- Angiogenesis and VEGF in Cancer
- Synthesis and properties of polymers
- Polymer Science and PVC
- Pharmacological Receptor Mechanisms and Effects
- Pharmacovigilance and Adverse Drug Reactions
- Cellular Mechanics and Interactions
Université d'Angers
2018-2024
Centre National de la Recherche Scientifique
2017-2024
Inserm
2017-2024
University of Liège
2016-2021
Université Paris-Saclay
2021
Pharmac
2021
Institut Galien Paris-Saclay
2021
Centre de Recherches sur les Macromolécules Végétales
2017-2018
Micro et Nanomédecines translationnelles
2016-2018
Université Bretagne Loire
2017
Despite significant advances in melanoma therapy, low response rates and multidrug resistance (MDR) have been described, reducing the anticancer efficacy of administered molecules. Among causes to explain these resistances, decreased intratumoral pH is known potentiate MDR reduce sensitivity Nanomedicines widely exploited as carriers reversing Lipid nanocapsules (LNC) are nanoparticles that already demonstrated their ability improve cancer treatment. Here, LNC were modified with novel...
Screening on a relevant 3D tumor model enabled to discard unpromising nanocarriers and may help their opportune optimization successfully reach the target.