A5043670902- Influenza Virus Research Studies
- Bacterial biofilms and quorum sensing
- Animal Virus Infections Studies
- Viral gastroenteritis research and epidemiology
- Antibiotic Resistance in Bacteria
- Microbial infections and disease research
- Bacteriophages and microbial interactions
- Building materials and conservation
- Respiratory viral infections research
- Antibiotic Use and Resistance
- Antimicrobial Resistance in Staphylococcus
- Oral microbiology and periodontitis research
- Infectious Encephalopathies and Encephalitis
- Animal Disease Management and Epidemiology
- Genomics and Phylogenetic Studies
- Insect and Pesticide Research
- Mycobacterium research and diagnosis
Animal and Plant Health Agency
2021-2024
Manchester Metropolitan University
2019-2021
Royal Veterinary College
2021
Royal Society
2021
The UK and Europe have seen successive outbreaks of highly pathogenic avian influenza across the 2020/21 2021/22 autumn/winter seasons. Understanding both epidemiology transmission these viruses in different species is critical to aid mitigating measures where cause extensive mortalities land- waterfowl. Infection can result mild or asymptomatic outcomes, acute infections that high morbidity mortality levels. Definition disease outcome great importance understanding role play maintenance...
We report a disease and mortality event involving swans, seals, fox at wildlife rehabilitation center in the United Kingdom during late 2020. Five swans had onset of highly pathogenic avian influenza virus infection while captivity. Subsequently, 5 seals died (or were euthanized) after clinical disease. Avian-origin A subtype H5N8 was retrospectively determined as cause Infection manifested seizures, immunohistochemical molecular testing on postmortem samples detected neurologic distribution...
Phage therapy recently passed a key milestone with success of the first regulated clinical trial using systemic administration. In this single-arm non-comparative safety study, phages were administered intravenously to patients invasive Staphylococcus aureus infections no adverse reactions reported. Here, we examined features 78 lytic S. phages, most which propagated carnosus host modified be broadly susceptible staphylococcal phage infection. Use eliminates threat contamination prophage —...
Abstract Background Pseudomonas aeruginosa is a ubiquitous environmental microorganism and also common cause of infection. Its ability to survive in many different environments persistently colonize humans linked its presence biofilms formed on indwelling device surfaces. Biofilm promotes adhesion to, survival surfaces, protects from desiccation the actions antibiotics disinfectants. Results We examined genetic basis for biofilm production polystyrene at room (22 °C) body temperature (37...
Europe has experienced extensive outbreaks of highly pathogenic avian influenza (HPAI) during the autumn/winter 2020/21 season. These A viruses are transmissible and have infected over 1000 commercial backyard poultry premises in this period causing high mortality. The impact on wild bird populations also been significant, with 400 detections at least 47 different species reported across as being positive H5N8 virus. Although H5Nx combinations within H5 clade 2.3.4.4b detected, subtype...
Abstract Background Several outbreaks of highly pathogenic avian influenza (HPAI) caused by A virus subtype H5N8 have been reported in wild birds and poultry Europe during autumn 2020. Norway is one the few countries that had not previously detected HPAI virus, despite widespread active monitoring both domestic since 2005. Results We report detection a pink-footed goose ( Anser brachyrhynchus ), several other geese, ducks gull, from south-western November December Despite previous reports...
Abstract Pseudomonas aeruginosa is a ubiquitous environmental microorganism that also common cause of nosocomial infections vary in severity from chronic wound to pneumonia, bloodstream and sepsis. Its ability survive many different environments persistently colonize human tissue linked its presence within biofilms form on indwelling device surfaces such as plastics stainless steel. Biofilm promotes bacterial adhesion survival surfaces, reduces susceptibility desiccation, the actions...
Highly pathogenic avian influenza virus H5N1 clade 2.3.4.4b has been detected in great skuas ( Stercorarius skua ) across different colonies on islands off the shore of Scotland, Great Britain during summer 2021. Of eight submitted for post-mortem examination, seven have confirmed as being infected with this using a range diagnostic assays. Here we overview outbreak event that occurred species, listed species conservation concern Britain.
Abstract Background Pseudomonas aeruginosa is a ubiquitous environmental microorganism and also common cause of infection. Its ability to survive in many different environments persistently colonize humans linked its presence biofilms formed on indwelling device surfaces. Biofilm promotes adhesion to, survival surfaces, protects from desiccation the actions antibiotics disinfectants. Results We examined genetic basis for biofilm production polystyrene at room (22°C) body temperature (37°C)...