Abstract Cancer stem cells have been isolated from human gliomas and many other parenchymal tumors. It was previously assumed that established malignant cell lines also contain a rare subpopulation of cells. This study designed to investigate the fraction cancer in C6 glioma line using clonal population analyses, rather than isolating methods, which are based on specific markers. Interestingly, serum-containing medium, each 67 single plated per miniwell able generate clone subclones,...

Large cranial defects resulting from decompressive craniectomy performed for refractory intracranial hypertension after head trauma is one of the indications cranioplasty, and this procedure commonly 3 months craniectomy. However, large defect would lead to kinds complications early during phase these patients' recovery, which go against rehabilitation. This study retrospectively reviewed 23 patients undergoing cranioplasty (5-8 weeks craniectomy) in last 4 years with a detailed choice...

Metastasis is responsible for the rapid recurrence and poor survival of malignancies. Epithelial-mesenchymal transition (EMT) has a critical role in metastasis. Increasing evidence indicates that EMT can be regulated by microRNAs (miRNAs). The aim this study was to investigate miR-26b modulating epithelial-mesenchymal hepatocellular carcinoma (HCC), as well identify its underlying mechanism action. expression level assessed multiple HCC cell lines (HepG2, MHCC97H, Hep3B, MHCC97L, HCCC9810,...

Hepatocellular carcinoma (HCC) is one of the most common malignancies and a major cause cancer-related mortality in world. MicroRNAs (miRNAs) are small, noncoding RNAs that play essential roles various stages during cancer progression. The aim current study was to elucidate role miR-1269 pathogenesis HCC.The expression HCC cells tissues were determined by Real-time PCR analysis. Cell viability, colony formation anchorage-independent growth ability assays performed examine cell proliferative...

A growing amount of evidence supports that microRNA (miRNA) dysregulation is involved in cancer progression by directly downregulating multiple targets. Elucidating the underlying mechanism miRNA carcinogenesis may improve diagnostic and therapeutic strategies for malignancy. In current study, we found miR-105 expression was markedly downregulated both hepatocellular carcinoma (HCC) cell lines clinical HCC tissues, compared with normal human hepatocyte adjacent non-cancerous respectively....

Traumatic carotid cavernous fistula (TCCF) is a rare vascular complication of traumatic brain and facial injury. The purpose this study was to analyze the incidence disorder in different types basilar skull fracture, determine whether particular clinical factors impacted outcomes, discuss ways improving prognosis.We performed retrospective analysis cases with fracture or angiography-confirmed TCCF inpatients between 1999 2005, as well an rate each type fracture. For patients diagnosed TCCF,...

Intra-arterial chemotherapy (IAC) has become an essential technique for the treatment of advanced and relapsed intra-ocular retinoblastoma. The outcome IAC retinoblastoma is influenced by a variety medical non-medical factors. In this study, we aimed to examine determine factors influencing clinical outcome.A total 107 eyes 73 patients with undergoing between January 2011 April 2013 were retrospectively reviewed outcomes. outcomes determined using univariate multivariate analyses.After IAC,...

This case report presents the diagnosis and treatment process of a rare gastric perforation caused by short hair, leading to formation foreign body granuloma in child. The patient was 3-year-old boy who admitted hospital with persistent abdominal pain fever for more than 20 days. Ultrasound CT revealed inflammatory encapsulation cavity. Laparoscopic open surgeries were performed, revealing full-thickness wall approximately 2 mm diameter on greater curvature side stomach, which contact...

Renal artery branch stenosis induced hypertension (HTN) in children is rare and facing a great challenge diagnosis treatment. This study aimed to summarize the clinical features experience treatment of these children. Four diagnosed with renal HTN Cardiovascular Department Children's Hospital, Capital Institute Pediatrics were retrospectively summarized data, process treatment, prognosis. All patients male age 8 ~ 9 years. stage 2 most had significant symptoms. Routine examinations showed no...

Reports of bronchopulmonary sequestration in two or more locations within the ipsilateral thorax children are rare. To date, only a few clinical reports have described thoracoscopic two-port treatment for external lobe sequestration. We performed surgery on 7-month-old girl and identified abnormal masses left thoracic cavity: one located upper hilum lung other surface lower diaphragm. Both were resected using two-aperture pathologically confirmed as extralobar sequestrations. Preoperative...

<title>Abstract</title> <bold>Objective: </bold>To conduct a meta-analysis to determine the relative merits between robotic-assisted minimally invasive esophagectomy (RAMIE) and conventional video-assisted (MIE) in esophageal cancer patinents. <bold>METHODS: </bold>Eligible studies or databases for articles were retrieved via systematical search identify comparative reporting peri-operative outcomes RAMIE MIE. Pooled odds ratios (OR) standardized mean difference (SMD) with 95% confidence...

Retinoblastoma is the most common primary malignant intra-ocular tumor in children. Although intra-arterial chemotherapy (IAC) by selectively infusing through ophthalmic artery has become an essential technique treatment of advanced retinoblastoma children, outcome IAC as therapy for infants less than 3 months age remains unknown. In this retrospective study, we reviewed age.We retrospectively ten patients attending our center from January 2009 to September 2015 and beginning before months....

Boerhaave's syndrome refers to the spontaneous transmural rupture of esophagus.Primary repair may be performed in patients who present within 24 h perforation, and such cases have best outcomes as most complications not yet developed.However, treatment late perforations remains controversial.Various approaches strategies been described literature, but there is no uniform approach.We a case which patient underwent surgical 48 after acute event was subsequently treated successfully.The initial...

Abstract Background To investigate the long-term efficacy of minimally invasive Ivor Lewis esophagectomy (MIILE) in esophageal squamous cell carcinoma (ESCC) patients, a retrospective comparison quality life (QOL) and survival between patients who underwent MIILE left transthoracic (Sweet approach) was conducted. Methods A detailed database search identified 614 243 Sweet January 2011 December 2017. After propensity score matching, 216 paired cases were selected for statistical analysis....

To evaluate the effectiveness and complications of intra-arterial chemotherapy (IAC) for treating advanced refractory retinoblastoma (RB) in a large single-center cohort.Eighty-four eyes 62 consecutive patients with RB who received IAC were included study during January 2013 April 2015. These failed to respond adequately standard systemic (i.e., carboplatin, vincristine, etoposide) or without local therapy. Clinical outcomes these reviewed.All melphalan combined topotecan. The mean follow-up...

Abstract The present study is to evaluate the feasibility and efficacy of microwave ablation (MWA) combined with transcatheter arterial chemoembolization (TACE) in treatment for unresectable hepatoblastoma infants children. A total 17 patients PRETEXT stage III IV that was by conventional resection were included study. treated TACE, MWA, chemotherapy. All cases diagnosed computed tomography (CT) liver tumor biopsy before TACE procedure. received 2 courses 1 times MWA. Finally, several cycles...

Sir: Patients who have undergone sternum resection due to infection, tumor, or trauma need grafts stabilize the sternum. The requirements of an ideal replacement for reconstruction are availability, durability, nonreactivity, and resistance infection.1,2 In this communication, we describe our use autogenous rib reconstruct middle segment defect in three patients had partial resection. From March 2000 December 2005, with lesions presented medical center. Their data listed Table 1. Chest...