A5055352912- Single-cell and spatial transcriptomics
- Reproductive System and Pregnancy
- Genetic and phenotypic traits in livestock
- Immune cells in cancer
- Bone and Joint Diseases
- Bone Tumor Diagnosis and Treatments
- Ferroptosis and cancer prognosis
- Intracerebral and Subarachnoid Hemorrhage Research
- Circular RNAs in diseases
- Ocular Oncology and Treatments
- Reproductive Physiology in Livestock
- Immunotherapy and Immune Responses
- Protease and Inhibitor Mechanisms
- Bone health and treatments
- Mast cells and histamine
- Growth Hormone and Insulin-like Growth Factors
- Inflammatory Biomarkers in Disease Prognosis
- Neuroinflammation and Neurodegeneration Mechanisms
- Urticaria and Related Conditions
- Cancer-related molecular mechanisms research
Guizhou Provincial People's Hospital
2024-2025
Affiliated Eye Hospital of Wenzhou Medical College
2024
Wenzhou Medical University
2024
The People's Hospital of Guangxi Zhuang Autonomous Region
2011
Chongqing University
2011
Abstract We investigated subarachnoid haemorrhage (SAH) macrophage subpopulations and identified relevant key genes for improving diagnostic therapeutic strategies. SAH rat models were established, brain tissue samples underwent single‐cell transcriptome sequencing bulk RNA‐seq. Using data, distinct subpopulations, including a unique subset, identified. The hdWGCNA method revealed 160 macrophage‐related genes. Univariate analysis lasso regression selected 10 constructing model. Machine...
Spontaneous intracerebral hemorrhagic stroke (ICH) is a highly aggressive disease, with high incidence and mortality rate. Iron deposition following ICH leads to oxidative damage motor dysfunction, significantly impacting the overall quality of life for those affected. Here, polyphenolic nanomedicine, catechin-based polyphenol nanoparticles surface-modified by thiol-terminated poly(ethylene glycol) (CNPs@PEG), was developed through polymerization self-assembly catechin, natural compound in...
BackgroundThis study aims to explore the microtubule-associated gene signatures and molecular processes shared by osteonecrosis of femoral head (ONFH) osteosarcoma (OS).MethodsDatasets from TARGET GEO databases were subjected bioinformatics analysis, including functional enrichment analysis genes ONFH OS. Prognostic identified using univariate multivariate Cox regression analyses develop a risk score model for predicting overall survival immune characteristics. Furthermore, LASSO SVM-RFE...
Uveal melanoma (UM) is a rare and deadly eye cancer with high metastatic potential. Despite the predominance of malignant cells within tumor microenvironment, heterogeneity underlying molecular features remain to be fully characterized.
Objective To investigate the association between human leukocyte antigen DR (HLA-DR) gene and HLA-G polymorphisms total IgE levels in children with asthma. Methods Eighty-four unrelated asthmatic individuals 168 healthy controls without asthma or atopy were involved study.All had their serum measured UniCAP Pharmacia system, skin-prick test 10 kinds of inhalant allergens was taken among asthmatics children.HLA oligonucleotide array used to detect 21 frequencies HLA-DR mass ARRAY...