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Research Areas
- SARS-CoV-2 and COVID-19 Research
- Intramuscular injections and effects
- Animal Virus Infections Studies
- Heparin-Induced Thrombocytopenia and Thrombosis
- vaccines and immunoinformatics approaches
Abstract Background SOBERANA 02 is a COVID-19 conjugate vaccine candidate based on SARS-CoV-2 recombinant RBD conjugated to tetanus toxoid. Plus antigen dimeric-RBD. Here we report safety, reactogenicity and immunogenicity from phase I IIa clinical trials using two-doses (homologous protocol) three-doses (homologous) or heterologous (with Plus) protocols. Method We performed an open-label, monocentric, sequential adaptive for evaluating exploring of in two formulations (15 25 μg) 40...
10.1101/2021.11.14.21266309
preprint
EN
cc-by-nd
medRxiv (Cold Spring Harbor Laboratory)
2021-11-15
10.1016/j.jvacx.2024.100595
article
EN
cc-by
Vaccine X
2024-12-06
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