Otto Cruz-Sui

ORCID: 0000-0003-4029-4253
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About
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Research Areas
  • SARS-CoV-2 and COVID-19 Research
  • Intramuscular injections and effects
  • Animal Virus Infections Studies
  • Heparin-Induced Thrombocytopenia and Thrombosis
  • vaccines and immunoinformatics approaches

Abstract Background SOBERANA 02 is a COVID-19 conjugate vaccine candidate based on SARS-CoV-2 recombinant RBD conjugated to tetanus toxoid. Plus antigen dimeric-RBD. Here we report safety, reactogenicity and immunogenicity from phase I IIa clinical trials using two-doses (homologous protocol) three-doses (homologous) or heterologous (with Plus) protocols. Method We performed an open-label, monocentric, sequential adaptive for evaluating exploring of in two formulations (15 25 μg) 40...

10.1101/2021.11.14.21266309 preprint EN cc-by-nd medRxiv (Cold Spring Harbor Laboratory) 2021-11-15
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